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    TBL1X transducin beta like 1 X-linked [ Bos taurus (domestic cattle) ]

    Gene ID: 515972, updated on 30-Jan-2025

    Summary

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    Gene symbol
    TBL1X
    Gene description
    transducin beta like 1 X-linked
    See related
    BGD:BT26461; EnsemblRapid:ENSBTAG00070016497 EnsemblRapid:ENSBTAG00070026407
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human all
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    Genomic context

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    See TBL1X in Genome Data Viewer
    Location:
    chromosome: X, chromosome: Y
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (133338879..133585555, complement)
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) Y NC_082638.1 (6537172..6782468)

    Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene shroom family member 2 Neighboring gene G protein-coupled receptor 143 Neighboring gene uncharacterized LOC132344369 Neighboring gene uncharacterized LOC132344370 Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene microRNA mir-584-8

    Chromosome Y - NC_082638.1Genomic Context describing neighboring genes Neighboring gene microRNA mir-584-8 Neighboring gene uncharacterized LOC132344370 Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene G protein-coupled receptor 143 Neighboring gene eukaryotic translation initiation factor 1A, Y-linked

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Characterization of the bovine pseudoautosomal boundary: Documenting the evolutionary history of mammalian sex chromosomes. Van Laere AS, et al. Genome Res, 2008 Dec. PMID 18981267, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of histone deacetylase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    F-box-like/WD repeat-containing protein TBL1X
    Names
    transducin beta like 1X-linked
    transducin beta-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145232.1 → NP_001138704.1  F-box-like/WD repeat-containing protein TBL1X

      Status: PROVISIONAL

      Source sequence(s)
      FJ195366
      UniProtKB/TrEMBL
      B7TCI5, G3X7D0
      Related
      ENSBTAP00070035509.1, ENSBTAT00070059841.1
      Conserved Domains (3) summary
      cd00200
      Location:178 → 484
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:186 → 233
      7WD40; WD40 repeat [structural motif]
      pfam08513
      Location:6 → 32
      LisH; LisH

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      133338879..133585555 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059883400.1 → XP_059739383.1  F-box-like/WD repeat-containing protein TBL1X isoform X1

      UniProtKB/TrEMBL
      B7TCI5, G3X7D0

    2. XM_059883399.1 → XP_059739382.1  F-box-like/WD repeat-containing protein TBL1X isoform X1

      UniProtKB/TrEMBL
      B7TCI5, G3X7D0

    3. XM_059883401.1 → XP_059739384.1  F-box-like/WD repeat-containing protein TBL1X isoform X2

    4. XM_059883396.1 → XP_059739379.1  F-box-like/WD repeat-containing protein TBL1X isoform X1

      UniProtKB/TrEMBL
      B7TCI5, G3X7D0
      Related
      ENSBTAP00070035517.1, ENSBTAT00070059852.1

    5. XM_059883397.1 → XP_059739380.1  F-box-like/WD repeat-containing protein TBL1X isoform X1

      UniProtKB/TrEMBL
      B7TCI5, G3X7D0

    6. XM_059883398.1 → XP_059739381.1  F-box-like/WD repeat-containing protein TBL1X isoform X1

      UniProtKB/TrEMBL
      B7TCI5, G3X7D0

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_082638.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      6537172..6782468
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024987975.2 → XP_024843743.1  F-box-like/WD repeat-containing protein TBL1X isoform X1

      UniProtKB/TrEMBL
      B7TCI5, G3X7D0
      Conserved Domains (3) summary
      cd00200
      Location:178 → 484
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:186 → 233
      7WD40; WD40 repeat [structural motif]
      pfam08513
      Location:6 → 32
      LisH; LisH

    2. XM_059883982.1 → XP_059739965.1  F-box-like/WD repeat-containing protein TBL1X isoform X1

      UniProtKB/TrEMBL
      B7TCI5, G3X7D0

    3. XM_024987972.2 → XP_024843740.1  F-box-like/WD repeat-containing protein TBL1X isoform X1

      UniProtKB/TrEMBL
      B7TCI5, G3X7D0
      Related
      ENSBTAP00070021775.1, ENSBTAT00070037028.1
      Conserved Domains (3) summary
      cd00200
      Location:178 → 484
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:186 → 233
      7WD40; WD40 repeat [structural motif]
      pfam08513
      Location:6 → 32
      LisH; LisH

    4. XM_024987977.2 → XP_024843745.1  F-box-like/WD repeat-containing protein TBL1X isoform X2

      Conserved Domains (2) summary
      cd00200
      Location:91 → 397
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:99 → 146
      7WD40; WD40 repeat [structural motif]

    5. XM_024987974.2 → XP_024843742.1  F-box-like/WD repeat-containing protein TBL1X isoform X1

      UniProtKB/TrEMBL
      B7TCI5, G3X7D0
      Conserved Domains (3) summary
      cd00200
      Location:178 → 484
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:186 → 233
      7WD40; WD40 repeat [structural motif]
      pfam08513
      Location:6 → 32
      LisH; LisH

    6. XM_059883983.1 → XP_059739966.1  F-box-like/WD repeat-containing protein TBL1X isoform X1

      UniProtKB/TrEMBL
      B7TCI5, G3X7D0

    7. XM_024987976.2 → XP_024843744.1  F-box-like/WD repeat-containing protein TBL1X isoform X1

      UniProtKB/TrEMBL
      B7TCI5, G3X7D0
      Conserved Domains (3) summary
      cd00200
      Location:178 → 484
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:186 → 233
      7WD40; WD40 repeat [structural motif]
      pfam08513
      Location:6 → 32
      LisH; LisH
    Nucleotide Protein Strain
    Heading Accession and Version

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