U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    GRB7 growth factor receptor bound protein 7 [ Bos taurus (domestic cattle) ]

    Gene ID: 508847, updated on 27-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    GRB7provided by VGNC
    Official Full Name
    growth factor receptor bound protein 7provided by VGNC
    Primary source
    VGNC:VGNC:29632
    See related
    BGD:BT20770; Ensembl:ENSBTAG00000017366
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See GRB7 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (40104363..40113094)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene erb-b2 receptor tyrosine kinase 2 Neighboring gene migration and invasion enhancer 1 Neighboring gene IKAROS family zinc finger 3 Neighboring gene zona pellucida binding protein 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC138032

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    growth factor receptor-bound protein 7
    Names
    GRB7 adapter protein
    epidermal growth factor receptor GRB-7

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001046014.1 → NP_001039479.1  growth factor receptor-bound protein 7

      See identical proteins and their annotated locations for NP_001039479.1

      Status: PROVISIONAL

      Source sequence(s)
      BC114669
      UniProtKB/Swiss-Prot
      Q1RMW5
      UniProtKB/TrEMBL
      A0AAA9TDN0
      Related
      ENSBTAP00000023091.3, ENSBTAT00000023091.5
      Conserved Domains (5) summary
      cd01787
      Location:101 → 184
      GRB7_RA; RA (RAS-associated like) domain of Grb7
      cd10413
      Location:425 → 532
      SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
      cd01259
      Location:225 → 347
      PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
      pfam00169
      Location:230 → 334
      PH; PH domain
      pfam08947
      Location:366 → 410
      BPS; BPS (Between PH and SH2)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      40104363..40113094
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059877874.1 → XP_059733857.1  growth factor receptor-bound protein 7 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TDN0
      Related
      ENSBTAP00000081759.1, ENSBTAT00000097982.1

    2. XM_015458829.3 → XP_015314315.1  growth factor receptor-bound protein 7 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LUD7, A0AAA9TDN0
      Related
      ENSBTAP00000060739.1, ENSBTAT00000069977.2
      Conserved Domains (4) summary
      cd01787
      Location:101 → 184
      GRB7_RA; RA (RAS-associated like) domain of Grb7
      cd10413
      Location:386 → 493
      SH2_Grb7; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 7 (Grb7) proteins
      cd01259
      Location:225 → 347
      PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
      pfam00169
      Location:230 → 334
      PH; PH domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1RMW5.1 GenPept UniProtKB/Swiss-Prot:Q1RMW5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.