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    ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 508582, updated on 30-Jan-2025

    Summary

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    Official Symbol
    ACAP1provided by VGNC
    Official Full Name
    ArfGAP with coiled-coil, ankyrin repeat and PH domains 1provided by VGNC
    Primary source
    VGNC:VGNC:25526
    See related
    EnsemblRapid:ENSBTAG00070017794
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    CENTB1
    Orthologs
    human mouse all
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    Genomic context

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    See ACAP1 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (27040187..27055358)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene neuralized E3 ubiquitin protein ligase 4 Neighboring gene uncharacterized LOC132343038 Neighboring gene potassium channel tetramerization domain containing 11 Neighboring gene transmembrane protein 95 Neighboring gene tyrosine kinase non receptor 1 Neighboring gene phospholipid scramblase 3 Neighboring gene transmembrane protein 256

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC157219

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
    Names
    centaurin, beta 1
    cnt-b1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001103234.1 → NP_001096704.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

      See identical proteins and their annotated locations for NP_001096704.1

      Status: PROVISIONAL

      Source sequence(s)
      BC142328
      UniProtKB/Swiss-Prot
      A5PK26
      UniProtKB/TrEMBL
      A0A3Q1M9L1
      Related
      ENSBTAP00070023680.1, ENSBTAT00070040122.1
      Conserved Domains (7) summary
      cd00204
      Location:593 → 697
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd13250
      Location:268 → 364
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      pfam00169
      Location:266 → 360
      PH; PH domain
      pfam01412
      Location:406 → 519
      ArfGap; Putative GTPase activating protein for Arf
      pfam12796
      Location:576 → 675
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:576 → 603
      ANK; ANK repeat [structural motif]
      cl12013
      Location:18 → 217
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      27040187..27055358
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005220204.5 → XP_005220261.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_005220261.1

      UniProtKB/TrEMBL
      A0A3Q1M9L1
      Related
      ENSBTAP00070023669.1, ENSBTAT00070040111.1
      Conserved Domains (5) summary
      cd00204
      Location:593 → 693
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd13250
      Location:268 → 364
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      sd00045
      Location:576 → 603
      ANK; ANK repeat [structural motif]
      pfam01412
      Location:406 → 519
      ArfGap; Putative GTPase activating protein for Arf
      cl12013
      Location:18 → 217
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    RNA

    1. XR_009491510.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A5PK26.1 GenPept UniProtKB/Swiss-Prot:A5PK26

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.