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    LEMD2 LEM domain nuclear envelope protein 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 518023, updated on 1-Jan-2025

    Summary

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    Official Symbol
    LEMD2provided by VGNC
    Official Full Name
    LEM domain nuclear envelope protein 2provided by VGNC
    Primary source
    VGNC:VGNC:30836
    See related
    BGD:BT22779; Ensembl:ENSBTAG00000015538
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See LEMD2 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (7898378..7914749, complement)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene inositol hexakisphosphate kinase 3 Neighboring gene uncharacterized LOC101905527 Neighboring gene motilin Neighboring gene uncharacterized LOC132343599

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chromatin DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear envelope organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LEM domain-containing protein 2
    Names
    LEM domain containing 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192479.1 → NP_001179408.1  LEM domain-containing protein 2

      See identical proteins and their annotated locations for NP_001179408.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000023
      UniProtKB/TrEMBL
      A0AAA9S085, E1B828
      Related
      ENSBTAP00000020642.5, ENSBTAT00000020642.6
      Conserved Domains (2) summary
      cd12941
      Location:4 → 41
      LEM_LEMD2; LEM (Lap2/Emerin/Man1) domain found in LEM domain-containing protein 2 (LEM2)
      pfam09402
      Location:270 → 485
      MSC; Man1-Src1p-C-terminal domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      7898378..7914749 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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