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    MAPK6 mitogen-activated protein kinase 6 [ Bos taurus (domestic cattle) ]

    Gene ID: 538094, updated on 1-Jan-2025

    Summary

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    Official Symbol
    MAPK6provided by VGNC
    Official Full Name
    mitogen-activated protein kinase 6provided by VGNC
    Primary source
    VGNC:VGNC:31221
    See related
    Ensembl:ENSBTAG00000005865
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See MAPK6 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (58333416..58367478, complement)

    Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene protein FAM114A2-like Neighboring gene LEO1 homolog, Paf1/RNA polymerase II complex component Neighboring gene RNA polymerase-associated protein LEO1 Neighboring gene tropomodulin 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables MAP kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase 6
    XP_002691011.2
    XP_005211938.1
    XP_015328687.1
    XP_024853799.1
    XP_059746838.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      58333416..58367478 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002690965.7 → XP_002691011.2  mitogen-activated protein kinase 6 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TZ15, G5E577
      Related
      ENSBTAP00000102767.1, ENSBTAT00000112070.1
      Conserved Domains (1) summary
      cd07854
      Location:14 → 355
      STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

    2. XM_024998031.2 → XP_024853799.1  mitogen-activated protein kinase 6 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TZ15, G5E577
      Conserved Domains (1) summary
      cd07854
      Location:14 → 355
      STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

    3. XM_005211881.5 → XP_005211938.1  mitogen-activated protein kinase 6 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TZ15, G5E577
      Related
      ENSBTAP00000007709.3, ENSBTAT00000007709.5
      Conserved Domains (1) summary
      cd07854
      Location:14 → 355
      STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

    4. XM_015473201.3 → XP_015328687.1  mitogen-activated protein kinase 6 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TZ15, G5E577
      Conserved Domains (1) summary
      cd07854
      Location:14 → 355
      STKc_MAPK4_6; Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinases 4 (also called ERK4) and 6 (also called ERK3)

    5. XM_059890855.1 → XP_059746838.1  mitogen-activated protein kinase 6 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version

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