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    LONP2 lon peptidase 2, peroxisomal [ Bos taurus (domestic cattle) ]

    Gene ID: 541085, updated on 29-Jan-2025

    Summary

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    Official Symbol
    LONP2provided by VGNC
    Official Full Name
    lon peptidase 2, peroxisomalprovided by VGNC
    Primary source
    VGNC:VGNC:30948
    See related
    BGD:BT16284; Ensembl:ENSBTAG00000010867
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See LONP2 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (16674859..16759579)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene non-POU domain-containing octamer-binding protein-like Neighboring gene ATP binding cassette subfamily C member 12 Neighboring gene ATP binding cassette subfamily C member 11 Neighboring gene siah E3 ubiquitin protein ligase 1 Neighboring gene uncharacterized LOC132342799

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC128838

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP-dependent peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein quality control for misfolded or incompletely synthesized proteins IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein targeting to peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in peroxisomal matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lon protease homolog 2, peroxisomal
    Names
    lon protease 2
    lon protease-like protein 2
    peroxisomal Lon protease homolog 2
    NP_001029895.1
    XP_010812849.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034723.1 → NP_001029895.1  lon protease homolog 2, peroxisomal

      See identical proteins and their annotated locations for NP_001029895.1

      Status: PROVISIONAL

      Source sequence(s)
      BC104547
      UniProtKB/Swiss-Prot
      Q3SX23
      UniProtKB/TrEMBL
      A0A3Q1M4F9
      Related
      ENSBTAP00070042903.1, ENSBTAT00070070449.1
      Conserved Domains (4) summary
      COG0466
      Location:11 → 838
      Lon; ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]
      cl19481
      Location:4 → 144
      LON; Found in ATP-dependent protease La (LON)
      pfam00004
      Location:371 → 513
      AAA; ATPase family associated with various cellular activities (AAA)
      cl21678
      Location:634 → 837
      ChlI; Subunit ChlI of Mg-chelatase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      16674859..16759579
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010814547.4 → XP_010812849.1  lon protease homolog 2, peroxisomal isoform X1

      UniProtKB/TrEMBL
      A0A3Q1M4F9
      Conserved Domains (5) summary
      COG0714
      Location:321 → 622
      MoxR; MoxR-like ATPase [General function prediction only]
      cl19481
      Location:4 → 144
      LON; Found in ATP-dependent protease La (LON)
      pfam00004
      Location:371 → 513
      AAA; ATPase family associated with various cellular activities (AAA)
      pfam02190
      Location:13 → 220
      LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain
      cl21678
      Location:634 → 726
      ChlI; Subunit ChlI of Mg-chelatase
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3SX23.1 GenPept UniProtKB/Swiss-Prot:Q3SX23

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.