TMX2 thioredoxin related transmembrane protein 2 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: TMX2provided by VGNC
Official Full Name: thioredoxin related transmembrane protein 2provided by VGNC
Primary source: VGNC:VGNC:54897
See related: BGD:BT30045; Ensembl:ENSBTAG00000002404
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: TXNDC14
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	15	NC_037342.1 (80941174..80949870)

Chromosome 15 - NC_037342.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables disulfide oxidoreductase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in brain development	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane-bounded organelle	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: thioredoxin-related transmembrane protein 2

Names: thioredoxin domain containing 14; thioredoxin domain-containing protein 14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001015558.1 → NP_001015558.1 thioredoxin-related transmembrane protein 2

See identical proteins and their annotated locations for NP_001015558.1

Status: PROVISIONAL

Source sequence(s)

BT021083

UniProtKB/TrEMBL

G1K152

Conserved Domains (2) summary

cl00388
Location:109 → 210

Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

cl00437
Location:1 → 78

Zip; ZIP Zinc transporter

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

Range

80941174..80949870

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005200957.3 → XP_005201014.1 thioredoxin-related transmembrane protein 2 isoform X1

See identical proteins and their annotated locations for XP_005201014.1

UniProtKB/Swiss-Prot

Q2TBU2, Q5E937

UniProtKB/TrEMBL

G1K152

Related

ENSBTAP00070026676.1, ENSBTAT00070044316.1

Conserved Domains (1) summary

cd02962
Location:109 → 259

TMX2; TMX2 family; composed of proteins similar to human TMX2, a 372-amino acid TRX-related transmembrane protein, identified and characterized through the cloning of its cDNA from a human fetal library. It contains a TRX domain but the redox active CXXC motif ...