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    WDR45 WD repeat domain 45 [ Bos taurus (domestic cattle) ]

    Gene ID: 539190, updated on 27-Dec-2024

    Summary

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    Official Symbol
    WDR45provided by VGNC
    Official Full Name
    WD repeat domain 45provided by VGNC
    Primary source
    VGNC:VGNC:50134
    See related
    BGD:BT12793; Ensembl:ENSBTAG00000002563
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See WDR45 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (87156566..87161808, complement)

    Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 120 Neighboring gene PRA1 domain family member 2 Neighboring gene large ribosomal subunit protein eL36 Neighboring gene G-patch domain and KOW motifs Neighboring gene uncharacterized LOC101906207 Neighboring gene microRNA mir-2486

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC139750

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatidylinositol-3,5-bisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-3-phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in autophagy of mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nucleophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein lipidation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein localization to phagophore assembly site IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extrinsic component of membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in phagophore assembly site membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    WD repeat domain phosphoinositide-interacting protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076151.1 → NP_001069619.1  WD repeat domain phosphoinositide-interacting protein 4

      See identical proteins and their annotated locations for NP_001069619.1

      Status: PROVISIONAL

      Source sequence(s)
      BC122648
      UniProtKB/TrEMBL
      A0AAA9TYM1, Q0IIH0
      Related
      ENSBTAP00000103449.1, ENSBTAT00000115095.1
      Conserved Domains (2) summary
      sd00039
      Location:196 → 232
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:187 → 274
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      87156566..87161808 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005228157.5 → XP_005228214.1  WD repeat domain phosphoinositide-interacting protein 4 isoform X1

      UniProtKB/TrEMBL
      A0AAA9S0I8
      Related
      ENSBTAP00000077148.1, ENSBTAT00000127394.1
      Conserved Domains (2) summary
      sd00039
      Location:196 → 232
      7WD40; WD40 repeat [structural motif]
      cl25539
      Location:187 → 274
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein Strain
    Heading Accession and Version

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