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    ACSM1 acyl-CoA synthetase medium chain family member 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 282576, updated on 27-Dec-2024

    Summary

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    Official Symbol
    ACSM1provided by VGNC
    Official Full Name
    acyl-CoA synthetase medium chain family member 1provided by VGNC
    Primary source
    VGNC:VGNC:50046
    See related
    BGD:BT10990; Ensembl:ENSBTAG00000001417
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    BUCS1
    Orthologs
    human mouse all
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    Genomic context

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    See ACSM1 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (18233946..18298234)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene acyl-CoA synthetase medium chain family member 5 Neighboring gene acyl-CoA synthetase medium-chain family member 2B Neighboring gene transport and Golgi organization protein 1 homolog Neighboring gene cytochrome c oxidase subunit 7A2, mitochondrial-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Purification, characterization, and cDNA cloning of lipoate-activating enzyme from bovine liver. Fujiwara K, et al. J Biol Chem, 2001 Aug 3. PMID 11382754
    2. Isolation and sequencing of cDNAs for the XL-I and XL-III forms of bovine liver xenobiotic-metabolizing medium-chain fatty acid:CoA ligase. Vessey DA, et al. J Biochem Mol Toxicol, 2000. PMID 10561077
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC133979

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables fatty acid ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables fatty-acyl-CoA synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in acyl-CoA metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    acyl-coenzyme A synthetase ACSM1, mitochondrial
    Names
    XL-III
    XM-ligase 3
    benzoate--CoA ligase
    butyrate--CoA ligase 1
    butyryl Coenzyme A synthetase 1
    butyryl-coenzyme A synthetase 1
    lipoate-activating enzyme
    middle-chain acyl-CoA synthetase 1
    xenobiotic/medium-chain fatty acid:CoA ligase XL-3
    NP_777107.1
    XP_005224748.1
    XP_005224749.1
    XP_015315799.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174682.2 → NP_777107.1  acyl-coenzyme A synthetase ACSM1, mitochondrial

      See identical proteins and their annotated locations for NP_777107.1

      Status: PROVISIONAL

      Source sequence(s)
      AB048289
      UniProtKB/Swiss-Prot
      Q32LF8, Q9BEA2, Q9TVB5, Q9XT43
      Related
      ENSBTAP00000001859.4, ENSBTAT00000001859.6
      Conserved Domains (2) summary
      COG0365
      Location:39 → 571
      Acs; Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase [Lipid transport and metabolism]
      cl17068
      Location:46 → 573
      AFD_class_I; Adenylate forming domain, Class I superfamily

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      18233946..18298234
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015460313.3 → XP_015315799.1  acyl-coenzyme A synthetase ACSM1, mitochondrial isoform X1

      UniProtKB/Swiss-Prot
      Q32LF8, Q9BEA2, Q9TVB5, Q9XT43
      UniProtKB/TrEMBL
      F1MPP7
      Conserved Domains (2) summary
      COG0365
      Location:39 → 571
      Acs; Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase [Lipid transport and metabolism]
      cl17068
      Location:46 → 573
      AFD_class_I; Adenylate forming domain, Class I superfamily

    2. XM_005224692.5 → XP_005224749.1  acyl-coenzyme A synthetase ACSM1, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_005224749.1

      UniProtKB/Swiss-Prot
      Q32LF8, Q9BEA2, Q9TVB5, Q9XT43
      UniProtKB/TrEMBL
      F1MPP7
      Conserved Domains (2) summary
      COG0365
      Location:39 → 571
      Acs; Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase [Lipid transport and metabolism]
      cl17068
      Location:46 → 573
      AFD_class_I; Adenylate forming domain, Class I superfamily

    3. XM_005224691.5 → XP_005224748.1  acyl-coenzyme A synthetase ACSM1, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_005224748.1

      UniProtKB/Swiss-Prot
      Q32LF8, Q9BEA2, Q9TVB5, Q9XT43
      UniProtKB/TrEMBL
      F1MPP7
      Conserved Domains (2) summary
      COG0365
      Location:39 → 571
      Acs; Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase [Lipid transport and metabolism]
      cl17068
      Location:46 → 573
      AFD_class_I; Adenylate forming domain, Class I superfamily
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9BEA2.2 GenPept UniProtKB/Swiss-Prot:Q9BEA2

    Gene LinkOut

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