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    POLR2E RNA polymerase II, I and III subunit E [ Bos taurus (domestic cattle) ]

    Gene ID: 512971, updated on 1-Jan-2025

    Summary

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    Official Symbol
    POLR2Eprovided by VGNC
    Official Full Name
    RNA polymerase II, I and III subunit Eprovided by VGNC
    Primary source
    VGNC:VGNC:33139
    See related
    BGD:BT26508; Ensembl:ENSBTAG00000020776
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See POLR2E in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (43579121..43583591, complement)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily A member 7 Neighboring gene uncharacterized LOC132345740 Neighboring gene Rho GTPase activating protein 45 Neighboring gene glutathione peroxidase 4 Neighboring gene strawberry notch homolog 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A Mediator-responsive form of metazoan RNA polymerase II. Hu X, et al. Proc Natl Acad Sci U S A, 2006 Jun 20. PMID 16769904, Free PMC Article
    2. Structure of transcribing mammalian RNA polymerase II. Bernecky C, et al. Nature, 2016 Jan 28. PMID 26789250
    3. Identification of DNA replication and cell cycle proteins that interact with PCNA. Loor G, et al. Nucleic Acids Res, 1997 Dec 15. PMID 9396813, Free PMC Article
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC134612

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase I activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase III activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase I complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of RNA polymerase II, core complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of RNA polymerase III complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA-directed RNA polymerases I, II, and III subunit RPABC1
    Names
    DNA-directed RNA polymerase II subunit E
    RNA polymerase II subunit E
    RNA polymerases I, II, and III subunit ABC1
    RPB5 homolog
    polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
    NP_001033182.1
    XP_024849919.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038093.2 → NP_001033182.1  DNA-directed RNA polymerases I, II, and III subunit RPABC1

      See identical proteins and their annotated locations for NP_001033182.1

      Status: PROVISIONAL

      Source sequence(s)
      BC111280
      UniProtKB/Swiss-Prot
      Q2T9T3
      UniProtKB/TrEMBL
      A0AAA9TCG7
      Related
      ENSBTAP00000095750.1, ENSBTAT00000127449.1
      Conserved Domains (1) summary
      PLN03111
      Location:1 → 209
      PLN03111; DNA-directed RNA polymerase II subunit family protein; Provisional

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      43579121..43583591 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024994151.2 → XP_024849919.1  DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X1

      UniProtKB/TrEMBL
      F2Z4J4
      Related
      ENSBTAP00000027684.4, ENSBTAT00000027684.5
      Conserved Domains (1) summary
      cl29798
      Location:1 → 182
      RNA_pol_Rpb5_N; RNA polymerase Rpb5, N-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2T9T3.1 GenPept UniProtKB/Swiss-Prot:Q2T9T3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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