U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    SCNN1A sodium channel epithelial 1 subunit alpha [ Bos taurus (domestic cattle) ]

    Gene ID: 282348, updated on 29-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    SCNN1Aprovided by VGNC
    Official Full Name
    sodium channel epithelial 1 subunit alphaprovided by VGNC
    Primary source
    VGNC:VGNC:49961
    See related
    Ensembl:ENSBTAG00000002631
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SCNN1A in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (103993588..104018901)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene CD27 molecule Neighboring gene lymphotoxin beta receptor Neighboring gene uncharacterized LOC100847453 Neighboring gene TNF receptor superfamily member 1A Neighboring gene pleckstrin homology and RhoGEF domain containing G6

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Cloning of a bovine renal epithelial Na+ channel subunit. Fuller CM, et al. Am J Physiol, 1995 Sep. PMID 7573394
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ligand-gated sodium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of sodium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    amiloride-sensitive sodium channel subunit alpha
    Names
    SCNEA
    alpha-ENaC
    alpha-NaCH
    epithelial Na(+) channel subunit alpha
    nonvoltage-gated sodium channel 1 subunit alpha
    sodium channel epithelial 1 alpha subunit
    sodium channel, non-voltage-gated 1 alpha subunit
    sodium channel, nonvoltage-gated 1 alpha

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174598.3 → NP_777023.1  amiloride-sensitive sodium channel subunit alpha

      See identical proteins and their annotated locations for NP_777023.1

      Status: PROVISIONAL

      Source sequence(s)
      U14944
      UniProtKB/Swiss-Prot
      O02851, P55270
      Related
      ENSBTAP00070037408.1, ENSBTAT00070062553.1
      Conserved Domains (1) summary
      TIGR00859
      Location:34 → 628
      ENaC; sodium channel transporter

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      103993588..104018901
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024991370.2 → XP_024847138.1  amiloride-sensitive sodium channel subunit alpha isoform X1

      Conserved Domains (1) summary
      TIGR00859
      Location:66 → 660
      ENaC; sodium channel transporter

    2. XM_024991373.2 → XP_024847141.1  amiloride-sensitive sodium channel subunit alpha isoform X2

      UniProtKB/Swiss-Prot
      O02851, P55270
      Conserved Domains (1) summary
      TIGR00859
      Location:34 → 628
      ENaC; sodium channel transporter
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P55270.2 GenPept UniProtKB/Swiss-Prot:P55270

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.