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    CA14 carbonic anhydrase 14 [ Bos taurus (domestic cattle) ]

    Gene ID: 509027, updated on 29-Jan-2025

    Summary

    Official Symbol
    CA14provided by VGNC
    Official Full Name
    carbonic anhydrase 14provided by VGNC
    Primary source
    VGNC:VGNC:26652
    See related
    BGD:BT27580; Ensembl:ENSBTAG00000021481
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    NEW
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    Genomic context

    See CA14 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (20376449..20383625, complement)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene chromosome 3 C1orf54 homolog Neighboring gene aph-1 homolog A, gamma-secretase subunit Neighboring gene acidic nuclear phosphoprotein 32 family member E Neighboring gene uncharacterized LOC132344842 Neighboring gene pleckstrin homology domain containing O1

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables carbonate dehydratase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in one-carbon metabolic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    carbonic anhydrase 14
    Names
    carbonic anhydrase XIV
    NP_001179134.1
    XP_005203925.1
    XP_010801316.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192205.1NP_001179134.1  carbonic anhydrase 14 precursor

      See identical proteins and their annotated locations for NP_001179134.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000003
      UniProtKB/TrEMBL
      A0A3Q1MI50
      Related
      ENSBTAP00070048390.1, ENSBTAT00070079906.1
      Conserved Domains (1) summary
      cl00012
      Location:29278
      alpha_CA; Carbonic anhydrase alpha (vertebrate-like) group. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      20376449..20383625 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005203868.5XP_005203925.1  carbonic anhydrase 14 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MI50
      Conserved Domains (1) summary
      cl00012
      Location:6255
      alpha_CA; Carbonic anhydrase alpha (vertebrate-like) group. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...
    2. XM_010803014.4XP_010801316.1  carbonic anhydrase 14 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MI50, E1BHD3
      Related
      ENSBTAP00070048401.1, ENSBTAT00070079929.1
      Conserved Domains (1) summary
      cl00012
      Location:29278
      alpha_CA; Carbonic anhydrase alpha (vertebrate-like) group. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...