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    ID3 inhibitor of DNA binding 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 538690, updated on 27-Dec-2024

    Summary

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    Official Symbol
    ID3provided by VGNC
    Official Full Name
    inhibitor of DNA binding 3provided by VGNC
    Primary source
    VGNC:VGNC:30032
    See related
    BGD:BT11609; Ensembl:ENSBTAG00000030425
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ID3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (129292811..129298372)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene elongation factor 1-alpha, somatic form-like Neighboring gene uncharacterized LOC104971363 Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene E2F transcription factor 2 Neighboring gene U6 spliceosomal RNA Neighboring gene ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. ID3 regulates progesterone synthesis in bovine cumulus cells through modulation of mitochondrial function. Liu ZB, et al. Theriogenology, 2023 Oct 1. PMID 37393744
    2. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684
    3. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ID3 regulates progesterone synthesis in bovine cumulus cells through modulation of mitochondrial function.
      Title: ID3 regulates progesterone synthesis in bovine cumulus cells through modulation of mitochondrial function.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in circadian regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA-binding protein inhibitor ID-3
    Names
    inhibitor of DNA binding 3, HLH protein
    inhibitor of differentiation 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014950.1 → NP_001014950.1  DNA-binding protein inhibitor ID-3

      See identical proteins and their annotated locations for NP_001014950.1

      Status: PROVISIONAL

      Source sequence(s)
      BT021039
      UniProtKB/Swiss-Prot
      Q3T121, Q5E981
      Related
      ENSBTAP00000019148.3, ENSBTAT00000019148.5
      Conserved Domains (1) summary
      cd19693
      Location:23 → 83
      bHLH_dnHLH_ID3; basic helix-loop-helix (bHLH) domain found in DNA-binding protein inhibitor ID3 and similar proteins

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      129292811..129298372
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059875860.1 → XP_059731843.1  DNA-binding protein inhibitor ID-3 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5E981.1 GenPept UniProtKB/Swiss-Prot:Q5E981

    Gene LinkOut

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    Research Materials