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    NPRL2 NPR2 like, GATOR1 complex subunit [ Bos taurus (domestic cattle) ]

    Gene ID: 508487, updated on 27-Dec-2024

    Summary

    Official Symbol
    NPRL2provided by VGNC
    Official Full Name
    NPR2 like, GATOR1 complex subunitprovided by VGNC
    Primary source
    VGNC:VGNC:32214
    See related
    Ensembl:ENSBTAG00000019161
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    TUSC4
    Orthologs
    NEW
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    Genomic context

    See NPRL2 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (49997734..50001018)

    Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 115 Neighboring gene cytochrome b561 family member D2 Neighboring gene zinc finger MYND-type containing 10 Neighboring gene Ras association domain family member 1

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    General gene information

    Markers

    Clone Names

    • MGC128786

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to amino acid starvation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in negative regulation of TORC1 signaling IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in positive regulation of autophagy IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of GATOR1 complex IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in vacuolar membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    GATOR1 complex protein NPRL2
    Names
    GATOR complex protein NPRL2
    NPR2-like protein
    nitrogen permease regulator 2-like protein
    nitrogen permease regulator-like 2
    tumor suppressor candidate 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001015547.1NP_001015547.1  GATOR1 complex protein NPRL2

      See identical proteins and their annotated locations for NP_001015547.1

      Status: PROVISIONAL

      Source sequence(s)
      BT020747
      UniProtKB/TrEMBL
      A0A452DIV2, Q5EA22
      Related
      ENSBTAP00000025503.5, ENSBTAT00000025503.5
      Conserved Domains (1) summary
      cl24021
      Location:7370
      NPR3; Nitrogen Permease regulator of amino acid transport activity 3

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      49997734..50001018
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)