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    UGDH UDP-glucose 6-dehydrogenase [ Bos taurus (domestic cattle) ]

    Gene ID: 281564, updated on 1-Jan-2025

    Summary

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    Official Symbol
    UGDHprovided by VGNC
    Official Full Name
    UDP-glucose 6-dehydrogenaseprovided by VGNC
    Primary source
    VGNC:VGNC:36648
    See related
    BGD:BT16329; Ensembl:ENSBTAG00000014521
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See UGDH in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 6 NC_037333.1 (58585309..58620161, complement)

    Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L9 Neighboring gene lipoic acid synthetase Neighboring gene small integral membrane protein 14 Neighboring gene ubiquitin conjugating enzyme E2 K Neighboring gene U6atac minor spliceosomal RNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. cDNA cloning and expression of UDP-glucose dehydrogenase from bovine kidney. Lind T, et al. Glycobiology, 1999 Jun. PMID 10336992
    2. UDP-glucose dehydrogenase from bovine liver: primary structure and relationship to other dehydrogenases. Hempel J, et al. Protein Sci, 1994 Jul. PMID 7920253, Free PMC Article
    3. Amino acid sequence of the tryptic peptide containing the catalytic-site thiol group of bovine liver uridine diphosphate glucose dehydrogenase. Franzen B, et al. Biochem J, 1981 Dec 1. PMID 6896145, Free PMC Article
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables UDP-glucose 6-dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycosaminoglycan biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    UDP-glucose 6-dehydrogenase
    Names
    UDP-Glc dehydrogenase
    UDP-GlcDH
    UDP-glucose dehydrogenase
    UDPGDH
    NP_776636.1
    XP_005207890.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174211.3 → NP_776636.1  UDP-glucose 6-dehydrogenase

      See identical proteins and their annotated locations for NP_776636.1

      Status: PROVISIONAL

      Source sequence(s)
      AF095792
      UniProtKB/Swiss-Prot
      A6QR10, O77806, P12378
      Related
      ENSBTAP00000019302.4, ENSBTAT00000019302.6
      Conserved Domains (1) summary
      PLN02353
      Location:4 → 464
      PLN02353; probable UDP-glucose 6-dehydrogenase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      58585309..58620161 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005207833.4 → XP_005207890.1  UDP-glucose 6-dehydrogenase isoform X1

      See identical proteins and their annotated locations for XP_005207890.1

      UniProtKB/Swiss-Prot
      A6QR10, O77806, P12378
      Conserved Domains (1) summary
      PLN02353
      Location:4 → 464
      PLN02353; probable UDP-glucose 6-dehydrogenase
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P12378.2 GenPept UniProtKB/Swiss-Prot:P12378

    Gene LinkOut

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