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    CD3D CD3 delta subunit of T-cell receptor complex [ Bos taurus (domestic cattle) ]

    Gene ID: 281053, updated on 30-Jan-2025

    Summary

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    Official Symbol
    CD3Dprovided by VGNC
    Official Full Name
    CD3 delta subunit of T-cell receptor complexprovided by VGNC
    Primary source
    VGNC:VGNC:27028
    See related
    BGD:BT21167; EnsemblRapid:ENSBTAG00070030746
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CD3D in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (29019453..29023621, complement)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene myelin protein zero like 2 Neighboring gene CD3 epsilon subunit of T-cell receptor complex Neighboring gene CD3 gamma subunit of T-cell receptor complex Neighboring gene U6 spliceosomal RNA Neighboring gene ubiquitination factor E4A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Identification of a bovine surface antigen uniquely expressed on CD4-CD8- T cell receptor gamma/delta+ T lymphocytes. Clevers H, et al. Eur J Immunol, 1990 Apr. PMID 1971793
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC127796

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive thymic T cell selection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of alpha-beta T cell receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    T-cell surface glycoprotein CD3 delta chain
    Names
    CD3d molecule, delta (CD3-TCR complex)
    T-cell receptor T3 delta chain
    antigen CD3D, delta polypeptide (TiT3 complex)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034033.2 → NP_001029205.1  T-cell surface glycoprotein CD3 delta chain precursor

      Status: PROVISIONAL

      Source sequence(s)
      BC102857
      UniProtKB/Swiss-Prot
      Q28072, Q3SZH3
      UniProtKB/TrEMBL
      A0AAA9TMX5
      Related
      ENSBTAP00070042402.1, ENSBTAT00070069643.1
      Conserved Domains (2) summary
      pfam02189
      Location:143 → 161
      ITAM; Immunoreceptor tyrosine-based activation motif
      cl11960
      Location:26 → 91
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      29019453..29023621 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q28072.2 GenPept UniProtKB/Swiss-Prot:Q28072

    Gene LinkOut

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