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    CDK10 cyclin dependent kinase 10 [ Bos taurus (domestic cattle) ]

    Gene ID: 615171, updated on 1-Jan-2025

    Summary

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    Official Symbol
    CDK10provided by VGNC
    Official Full Name
    cyclin dependent kinase 10provided by VGNC
    Primary source
    VGNC:VGNC:27116
    See related
    BGD:BT28254; Ensembl:ENSBTAG00000033333
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CDK10 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (14557786..14575593)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene dipeptidase 1 Neighboring gene charged multivesicular body protein 1A Neighboring gene spermatogenesis associated 33 Neighboring gene uncharacterized LOC104974758 Neighboring gene spermatogenesis associated 2 like Neighboring gene VPS9 domain containing 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC134436

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cyclin-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclin-dependent kinase 10
    Names
    cell division protein kinase 10
    cyclin-dependent kinase (CDC2-like) 10
    NP_001033666.1
    XP_010812866.1
    XP_024834264.1
    XP_059732887.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038577.2 → NP_001033666.1  cyclin-dependent kinase 10

      See identical proteins and their annotated locations for NP_001033666.1

      Status: VALIDATED

      Source sequence(s)
      BC109954, EE370748
      UniProtKB/Swiss-Prot
      Q2TBL8
      UniProtKB/TrEMBL
      A0AAA9SRB8
      Related
      ENSBTAP00000044609.4, ENSBTAT00000047400.5
      Conserved Domains (1) summary
      cd07845
      Location:29 → 337
      STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      14557786..14575593
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059876904.1 → XP_059732887.1  cyclin-dependent kinase 10 isoform X2

      UniProtKB/TrEMBL
      A0AAA9SRB8

    2. XM_010814564.4 → XP_010812866.1  cyclin-dependent kinase 10 isoform X2

      See identical proteins and their annotated locations for XP_010812866.1

      UniProtKB/TrEMBL
      A0AAA9SRB8
      Conserved Domains (1) summary
      cd07845
      Location:1 → 268
      STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10

    3. XM_024978496.2 → XP_024834264.1  cyclin-dependent kinase 10 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SRB8
      Conserved Domains (1) summary
      cd07845
      Location:15 → 276
      STKc_CDK10; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 10
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2TBL8.1 GenPept UniProtKB/Swiss-Prot:Q2TBL8

    Gene LinkOut

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