These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

1. NM_001163188.1 → NP_001156660.1  mitochondrial tRNA-specific 2-thiouridylase 1

   See identical proteins and their annotated locations for NP_001156660.1

   Status: VALIDATED

   Description

   Transcript Variant: This variant (1) encodes a functional protein.

   Source sequence(s)

   CO882796, DN527350, DN549637, DT900631, EV675751

   UniProtKB/TrEMBL

   A0A3Q1MBS8, A0AAA9S3T2

   Related

   ENSBTAP00070010165.1, ENSBTAT00070017484.1

   Conserved Domains (2) summary

   cd01998
   Location:6 → 383

   tRNA_Me_trans; tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs. ...

   pfam03054
   Location:5 → 383

   tRNA_Me_trans; tRNA methyl transferase

RNA

1. NR_028029.1 RNA Sequence

   Status: VALIDATED

   Description

   Transcript Variant: This variant (2) lacks an internal segment in the CDS, as compared to variant 1, resulting in frame-shift and early translation termination. The transcript is a nonsense-mediated mRNA decay candidate and is unlikely to make a functional protein.

   Source sequence(s)

   CO875452, DN527350, EH164837

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Reference ARS-UCD2.0 Primary Assembly

Genomic

1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

   Range

   116635900..116651307

   Download

   GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

1. XM_010805829.4 → XP_010804131.1  mitochondrial tRNA-specific 2-thiouridylase 1 isoform X3

   Conserved Domains (2) summary

   cd01998
   Location:6 → 292

   tRNA_Me_trans; tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs. ...

   pfam03054
   Location:5 → 292

   tRNA_Me_trans; tRNA methyl transferase

2. XM_010805830.4 → XP_010804132.1  mitochondrial tRNA-specific 2-thiouridylase 1 isoform X4

   UniProtKB/TrEMBL

   Q32L44

   Conserved Domains (1) summary

   cl28063
   Location:37 → 243

   tRNA_Me_trans; tRNA methyl transferase

3. XM_024992212.2 → XP_024847980.1  mitochondrial tRNA-specific 2-thiouridylase 1 isoform X1

   Conserved Domains (1) summary

   pfam03054
   Location:92 → 446

   tRNA_Me_trans; tRNA methyl transferase

4. XM_059886739.1 → XP_059742722.1  mitochondrial tRNA-specific 2-thiouridylase 1 isoform X2

   UniProtKB/TrEMBL

   A0AAA9S3T2

The following Reference Sequences have been suppressed. Explain

These RefSeqs were suppressed for the cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related sequence links, or BLAST links (BLink), but may still be retrieved by clicking on their accession.version below.

1. NM_001038213.2: Suppressed sequence

   Description

   NM_001038213.2: This RefSeq was permanently suppressed because it was based on a chimeric sequence.