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    PICALM phosphatidylinositol binding clathrin assembly protein [ Bos taurus (domestic cattle) ]

    Gene ID: 513579, updated on 27-Dec-2024

    Summary

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    Official Symbol
    PICALMprovided by VGNC
    Official Full Name
    phosphatidylinositol binding clathrin assembly proteinprovided by VGNC
    Primary source
    VGNC:VGNC:32860
    See related
    BGD:BT18464; Ensembl:ENSBTAG00000001657
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PICALM in Genome Data Viewer
    Location:
    chromosome: 29
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 29 NC_037356.1 (9519657..9621125)

    Chromosome 29 - NC_037356.1Genomic Context describing neighboring genes Neighboring gene heat shock protein nuclear import factor hikeshi Neighboring gene embryonic ectoderm development Neighboring gene coiled-coil domain containing 83 Neighboring gene synaptotagmin like 2 Neighboring gene transfer RNA tryptophan (anticodon CCA)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC159850

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables SNARE binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables clathrin heavy chain binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-4,5-bisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in clathrin coat assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in clathrin-dependent endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic vesicle budding from presynaptic endocytic zone membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in clathrin-coated pit IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in clathrin-coated vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extrinsic component of presynaptic endocytic zone membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synaptic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylinositol-binding clathrin assembly protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001101977.1 → NP_001095447.1  phosphatidylinositol-binding clathrin assembly protein

      See identical proteins and their annotated locations for NP_001095447.1

      Status: PROVISIONAL

      Source sequence(s)
      BC151294
      UniProtKB/TrEMBL
      A7MB23, F1N605
      Related
      ENSBTAP00000057450.1, ENSBTAT00000083212.2
      Conserved Domains (2) summary
      pfam07651
      Location:19 → 282
      ANTH; ANTH domain
      pfam08287
      Location:265 → 344
      DASH_Spc19; Spc19

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037356.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      9519657..9621125
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059882885.1 → XP_059738868.1  phosphatidylinositol-binding clathrin assembly protein isoform X1

      UniProtKB/TrEMBL
      F1N605
      Related
      ENSBTAP00000059400.1, ENSBTAT00000079768.2

    2. XM_059882888.1 → XP_059738871.1  phosphatidylinositol-binding clathrin assembly protein isoform X4

      UniProtKB/TrEMBL
      F1N605

    3. XM_059882887.1 → XP_059738870.1  phosphatidylinositol-binding clathrin assembly protein isoform X3

      UniProtKB/TrEMBL
      F1N605

    4. XM_059882891.1 → XP_059738874.1  phosphatidylinositol-binding clathrin assembly protein isoform X9

      UniProtKB/TrEMBL
      F1N605

    5. XM_059882889.1 → XP_059738872.1  phosphatidylinositol-binding clathrin assembly protein isoform X6

      UniProtKB/TrEMBL
      F1N605

    6. XM_059882886.1 → XP_059738869.1  phosphatidylinositol-binding clathrin assembly protein isoform X2

      UniProtKB/TrEMBL
      F1N605

    7. XM_059882890.1 → XP_059738873.1  phosphatidylinositol-binding clathrin assembly protein isoform X7

      UniProtKB/TrEMBL
      F1N605

    8. XM_059882892.1 → XP_059738875.1  phosphatidylinositol-binding clathrin assembly protein isoform X11

      UniProtKB/TrEMBL
      F1N605

    9. XM_024987083.2 → XP_024842851.1  phosphatidylinositol-binding clathrin assembly protein isoform X5

      UniProtKB/TrEMBL
      F1N605
      Conserved Domains (1) summary
      pfam07651
      Location:24 → 282
      ANTH; ANTH domain

    10. XM_024987085.2 → XP_024842853.1  phosphatidylinositol-binding clathrin assembly protein isoform X10

      UniProtKB/TrEMBL
      F1N605
      Conserved Domains (1) summary
      pfam07651
      Location:24 → 282
      ANTH; ANTH domain

    11. XM_024987089.2 → XP_024842857.1  phosphatidylinositol-binding clathrin assembly protein isoform X15

      UniProtKB/TrEMBL
      A0A3Q1LVY5, F1N605
      Related
      ENSBTAP00000061348.2, ENSBTAT00000077265.2
      Conserved Domains (2) summary
      COG4223
      Location:268 → 366
      COG4223; Uncharacterized conserved protein [Function unknown]
      pfam07651
      Location:24 → 282
      ANTH; ANTH domain

    12. XM_024987087.2 → XP_024842855.1  phosphatidylinositol-binding clathrin assembly protein isoform X13

      UniProtKB/TrEMBL
      F1N605
      Conserved Domains (2) summary
      COG4223
      Location:268 → 366
      COG4223; Uncharacterized conserved protein [Function unknown]
      pfam07651
      Location:24 → 282
      ANTH; ANTH domain

    13. XM_024987084.2 → XP_024842852.1  phosphatidylinositol-binding clathrin assembly protein isoform X8

      UniProtKB/TrEMBL
      F1N605
      Conserved Domains (1) summary
      pfam07651
      Location:24 → 282
      ANTH; ANTH domain

    14. XM_024987088.2 → XP_024842856.1  phosphatidylinositol-binding clathrin assembly protein isoform X14

      UniProtKB/TrEMBL
      F1N605
      Conserved Domains (2) summary
      COG4223
      Location:268 → 366
      COG4223; Uncharacterized conserved protein [Function unknown]
      pfam07651
      Location:24 → 282
      ANTH; ANTH domain

    15. XM_024987086.2 → XP_024842854.1  phosphatidylinositol-binding clathrin assembly protein isoform X12

      UniProtKB/TrEMBL
      F1N605
      Conserved Domains (1) summary
      pfam07651
      Location:24 → 282
      ANTH; ANTH domain

    16. XM_024987091.2 → XP_024842859.1  phosphatidylinositol-binding clathrin assembly protein isoform X16

      UniProtKB/TrEMBL
      F1N605
      Conserved Domains (2) summary
      COG4223
      Location:268 → 366
      COG4223; Uncharacterized conserved protein [Function unknown]
      pfam07651
      Location:24 → 282
      ANTH; ANTH domain

    17. XM_024987096.2 → XP_024842864.1  phosphatidylinositol-binding clathrin assembly protein isoform X20

      UniProtKB/TrEMBL
      A0A3Q1N8I6, F1N605
      Related
      ENSBTAP00000067353.1, ENSBTAT00000072874.2
      Conserved Domains (2) summary
      COG4223
      Location:268 → 366
      COG4223; Uncharacterized conserved protein [Function unknown]
      pfam07651
      Location:24 → 282
      ANTH; ANTH domain

    18. XM_024987094.2 → XP_024842862.1  phosphatidylinositol-binding clathrin assembly protein isoform X18

      UniProtKB/TrEMBL
      F1N605
      Conserved Domains (2) summary
      COG4223
      Location:268 → 366
      COG4223; Uncharacterized conserved protein [Function unknown]
      pfam07651
      Location:24 → 282
      ANTH; ANTH domain

    19. XM_024987099.2 → XP_024842867.1  phosphatidylinositol-binding clathrin assembly protein isoform X22

      UniProtKB/TrEMBL
      F1N605
      Conserved Domains (2) summary
      COG4223
      Location:268 → 366
      COG4223; Uncharacterized conserved protein [Function unknown]
      pfam07651
      Location:24 → 282
      ANTH; ANTH domain

    20. XM_024987093.2 → XP_024842861.1  phosphatidylinositol-binding clathrin assembly protein isoform X17

      UniProtKB/TrEMBL
      F1N605
      Conserved Domains (2) summary
      COG4223
      Location:268 → 366
      COG4223; Uncharacterized conserved protein [Function unknown]
      pfam07651
      Location:24 → 282
      ANTH; ANTH domain

    21. XM_024987097.2 → XP_024842865.1  phosphatidylinositol-binding clathrin assembly protein isoform X21

      UniProtKB/TrEMBL
      F1N605
      Conserved Domains (2) summary
      COG4223
      Location:268 → 366
      COG4223; Uncharacterized conserved protein [Function unknown]
      pfam07651
      Location:24 → 282
      ANTH; ANTH domain

    22. XM_024987095.2 → XP_024842863.1  phosphatidylinositol-binding clathrin assembly protein isoform X19

      UniProtKB/TrEMBL
      F1N605
      Conserved Domains (2) summary
      COG4223
      Location:268 → 366
      COG4223; Uncharacterized conserved protein [Function unknown]
      pfam07651
      Location:24 → 282
      ANTH; ANTH domain

    23. XM_024987100.2 → XP_024842868.1  phosphatidylinositol-binding clathrin assembly protein isoform X23

      UniProtKB/TrEMBL
      F1N605
      Conserved Domains (2) summary
      COG4223
      Location:268 → 366
      COG4223; Uncharacterized conserved protein [Function unknown]
      pfam07651
      Location:24 → 282
      ANTH; ANTH domain
    Nucleotide Protein Strain
    Heading Accession and Version

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