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    MED25 mediator complex subunit 25 [ Bos taurus (domestic cattle) ]

    Gene ID: 533865, updated on 27-Dec-2024

    Summary

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    Official Symbol
    MED25provided by VGNC
    Official Full Name
    mediator complex subunit 25provided by VGNC
    Primary source
    VGNC:VGNC:31362
    See related
    BGD:BT27978; Ensembl:ENSBTAG00000008518
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See MED25 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (56177511..56194651)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132342714 Neighboring gene testis specific serine kinase substrate Neighboring gene adaptor related protein complex 2 subunit alpha 1 Neighboring gene fuzzy planar cell polarity protein Neighboring gene PTOV1 extended AT-hook containing adaptor protein Neighboring gene polynucleotide kinase 3'-phosphatase Neighboring gene AKT1 substrate 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC148420

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mediator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mediator of RNA polymerase II transcription subunit 25

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082445.1 → NP_001075914.1  mediator of RNA polymerase II transcription subunit 25

      See identical proteins and their annotated locations for NP_001075914.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133565
      UniProtKB/Swiss-Prot
      A2VE44
      UniProtKB/TrEMBL
      A0A3Q1N465
      Related
      ENSBTAP00000040773.4, ENSBTAT00000043183.4
      Conserved Domains (4) summary
      pfam11232
      Location:400 → 545
      Med25; Mediator complex subunit 25 PTOV activation and synapsin 2
      pfam11235
      Location:228 → 383
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      pfam11244
      Location:663 → 746
      Med25_NR-box; Mediator complex subunit 25 C-terminal NR box-containing
      pfam11265
      Location:13 → 225
      Med25_VWA; Mediator complex subunit 25 von Willebrand factor type A

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      56177511..56194651
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024978362.2 → XP_024834130.1  mediator of RNA polymerase II transcription subunit 25 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1N465, A0AAA9T762
      Related
      ENSBTAP00000093750.1, ENSBTAT00000131597.1
      Conserved Domains (4) summary
      pfam11232
      Location:400 → 545
      Med25; Mediator complex subunit 25 PTOV activation and synapsin 2
      pfam11235
      Location:228 → 383
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      pfam11244
      Location:663 → 765
      Med25_NR-box; Mediator complex subunit 25 C-terminal NR box-containing
      pfam11265
      Location:13 → 225
      Med25_VWA; Mediator complex subunit 25 von Willebrand factor type A

    2. XM_059876814.1 → XP_059732797.1  mediator of RNA polymerase II transcription subunit 25 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A2VE44.1 GenPept UniProtKB/Swiss-Prot:A2VE44

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