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    MCTS1 MCTS1 re-initiation and release factor [ Bos taurus (domestic cattle) ]

    Gene ID: 508412, updated on 30-Jan-2025

    Summary

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    Official Symbol
    MCTS1provided by VGNC
    Official Full Name
    MCTS1 re-initiation and release factorprovided by VGNC
    Primary source
    VGNC:VGNC:56930
    See related
    BGD:BT28797; EnsemblRapid:ENSBTAG00070025517
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See MCTS1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (5151418..5159309)

    Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene cullin 4B Neighboring gene insulin-like growth factor-binding protein 3 receptor Neighboring gene C1GALT1 specific chaperone 1 Neighboring gene cancer/testis antigen family 47 member B1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC137148

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in formation of translation preinitiation complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    malignant T-cell-amplified sequence 1
    Names
    MCT-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001046003.2 → NP_001039468.1  malignant T-cell-amplified sequence 1

      See identical proteins and their annotated locations for NP_001039468.1

      Status: PROVISIONAL

      Source sequence(s)
      BC112668
      UniProtKB/Swiss-Prot
      Q2KIE4
      UniProtKB/TrEMBL
      A0AAA9SPJ3
      Conserved Domains (2) summary
      cd11609
      Location:4 → 80
      MCT1_N; N-terminal domain of multiple copies T cell malignancies 1 and related proteins
      cd21155
      Location:80 → 175
      PUA_MCTS-1-like; PUA RNA-binding domain of malignant T cell-amplified sequence 1 and related proteins

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      5151418..5159309
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010821359.4 → XP_010819661.1  malignant T-cell-amplified sequence 1 isoform X1

      See identical proteins and their annotated locations for XP_010819661.1

      UniProtKB/TrEMBL
      A0AAA9SPJ3
      Conserved Domains (2) summary
      cd11609
      Location:18 → 94
      MCT1_N; N-terminal domain of multiple copies T cell malignancies 1 and related proteins
      cd21155
      Location:94 → 189
      PUA_MCTS-1-like; PUA RNA-binding domain of malignant T cell-amplified sequence 1 and related proteins

    2. XM_010821361.4 → XP_010819663.1  malignant T-cell-amplified sequence 1 isoform X2

      UniProtKB/TrEMBL
      A0AAA9SPJ3, A0AAF6ZHK0
      Related
      ENSBTAP00070034387.1, ENSBTAT00070057775.1
      Conserved Domains (3) summary
      cd11609
      Location:17 → 93
      MCT1_N; N-terminal domain of multiple copies T cell malignancies 1 and related proteins
      COG2016
      Location:36 → 190
      Tma20; Predicted ribosome-associated RNA-binding protein Tma20, contains PUA domain [Translation, ribosomal structure and biogenesis]
      cl00607
      Location:77 → 185
      PUA; PUA domain

    3. XM_024987838.2 → XP_024843606.1  malignant T-cell-amplified sequence 1 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SPJ3
      Conserved Domains (2) summary
      cd11609
      Location:18 → 94
      MCT1_N; N-terminal domain of multiple copies T cell malignancies 1 and related proteins
      cd21155
      Location:94 → 189
      PUA_MCTS-1-like; PUA RNA-binding domain of malignant T cell-amplified sequence 1 and related proteins

    4. XM_015461411.3 → XP_015316897.1  malignant T-cell-amplified sequence 1 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SPJ3
      Conserved Domains (2) summary
      cd11609
      Location:18 → 94
      MCT1_N; N-terminal domain of multiple copies T cell malignancies 1 and related proteins
      cd21155
      Location:94 → 189
      PUA_MCTS-1-like; PUA RNA-binding domain of malignant T cell-amplified sequence 1 and related proteins

    5. XM_015461412.3 → XP_015316898.1  malignant T-cell-amplified sequence 1 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1MW89, A0AAA9SPJ3
      Related
      ENSBTAP00070034395.1, ENSBTAT00070057794.1
      Conserved Domains (2) summary
      cd11609
      Location:5 → 81
      MCT1_N; N-terminal domain of multiple copies T cell malignancies 1 and related proteins
      cd21155
      Location:81 → 176
      PUA_MCTS-1-like; PUA RNA-binding domain of malignant T cell-amplified sequence 1 and related proteins
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2KIE4.1 GenPept UniProtKB/Swiss-Prot:Q2KIE4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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    Research Materials