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    Ssr1 signal sequence receptor subunit 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361233, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Ssr1provided by RGD
    Official Full Name
    signal sequence receptor subunit 1provided by RGD
    Primary source
    RGD:1310961
    See related
    EnsemblRapid:ENSRNOG00000014165 AllianceGenome:RGD:1310961
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ac2-238
    Summary
    Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human SSR1 (signal sequence receptor subunit 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Liver (RPKM 339.9), Adrenal (RPKM 284.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ssr1 in Genome Data Viewer
    Location:
    17p12
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (27039203..27067352)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (26833720..26861821)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (27496369..27512781)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene RIO kinase 1 Neighboring gene cancer antigen 1 Neighboring gene uncharacterized LOC120097850 Neighboring gene uncharacterized LOC134482845 Neighboring gene ras responsive element binding protein 1 Neighboring gene uncharacterized LOC134482846

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin. Zhang B, et al. Blood, 2011 Sep 22. PMID 21795745, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    translocon-associated protein subunit alpha
    Names
    SSR-alpha
    TRAP-alpha
    liver regeneration-related protein LRRG137
    signal sequence receptor subunit alpha
    signal sequence receptor, alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008891.3 → NP_001008891.2  translocon-associated protein subunit alpha precursor

      See identical proteins and their annotated locations for NP_001008891.2

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      F7F9K1, Q4V7D1
      Related
      ENSRNOP00000070389.3, ENSRNOT00000084090.3
      Conserved Domains (1) summary
      pfam03896
      Location:18 → 286
      TRAP_alpha; Translocon-associated protein (TRAP), alpha subunit

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      27039203..27067352
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039095878.2 → XP_038951806.1  translocon-associated protein subunit alpha isoform X1

      UniProtKB/TrEMBL
      A0A0G2K075
      Related
      ENSRNOP00000071334.3, ENSRNOT00000077994.3
      Conserved Domains (1) summary
      pfam03896
      Location:18 → 286
      TRAP_alpha; Translocon-associated protein (TRAP), alpha subunit

    2. XM_063276579.1 → XP_063132649.1  translocon-associated protein subunit alpha isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7TPJ0.1 GenPept UniProtKB/Swiss-Prot:Q7TPJ0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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