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    Mrps21 mitochondrial ribosomal protein S21 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 689432, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mrps21provided by RGD
    Official Full Name
    mitochondrial ribosomal protein S21provided by RGD
    Primary source
    RGD:1592330
    See related
    EnsemblRapid:ENSRNOG00000024845 AllianceGenome:RGD:1592330
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial small ribosomal subunit. Orthologous to human MRPS21 (mitochondrial ribosomal protein S21). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 314.8), Muscle (RPKM 307.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mrps21 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (186095729..186103351, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (183406791..183414413, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (197974758..197982385, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene regulation of nuclear pre-mRNA domain containing 2 Neighboring gene transfer RNA proline (anticodon AGG) 87 Neighboring gene pre-mRNA processing factor 3 Neighboring gene similar to human chromosome 1 open reading frame 54 Neighboring gene circadian associated repressor of transcription Neighboring gene aph-1 homolog A, gamma secretase subunit

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. Cavdar Koc E, et al. J Biol Chem, 2001 Jun 1. PMID 11279123
    2. Proteomic analysis of the mouse liver mitochondrial inner membrane. Da Cruz S, et al. J Biol Chem, 2003 Oct 17. PMID 12865426
    3. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, et al. Cell, 2003 Nov 26. PMID 14651853
    4. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article
    5. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    small ribosomal subunit protein bS21m
    Names
    28S ribosomal protein S21, mitochondrial
    NP_001119566.1
    NP_001274045.1
    XP_006233045.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001126094.2 → NP_001119566.1  small ribosomal subunit protein bS21m

      See identical proteins and their annotated locations for NP_001119566.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      CB808996, JAXUCZ010000002
      UniProtKB/TrEMBL
      B2RYT0, F7FNX8
      Conserved Domains (1) summary
      TIGR00030
      Location:10 → 66
      S21p; ribosomal protein S21

    2. NM_001287116.1 → NP_001274045.1  small ribosomal subunit protein bS21m

      See identical proteins and their annotated locations for NP_001274045.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      BC166891, CB808996
      UniProtKB/TrEMBL
      B2RYT0, F7FNX8
      Related
      ENSRNOP00000038594.4, ENSRNOT00000034074.7
      Conserved Domains (1) summary
      TIGR00030
      Location:10 → 66
      S21p; ribosomal protein S21

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      186095729..186103351 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006232983.5 → XP_006233045.1  small ribosomal subunit protein bS21m isoform X1

      See identical proteins and their annotated locations for XP_006233045.1

      UniProtKB/TrEMBL
      B2RYT0, F7FNX8
      Conserved Domains (1) summary
      TIGR00030
      Location:10 → 66
      S21p; ribosomal protein S21
    Nucleotide Protein Strain
    Heading Accession and Version

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