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    Smim19 small integral membrane protein 19 [ Mus musculus (house mouse) ]

    Gene ID: 102032, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Smim19provided by MGI
    Official Full Name
    small integral membrane protein 19provided by MGI
    Primary source
    MGI:MGI:2142501
    See related
    Ensembl:ENSMUSG00000031534 AllianceGenome:MGI:2142501
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EST-c39
    Summary
    Predicted to be located in membrane. Is expressed in germ cell of testis. Orthologous to human SMIM19 (small integral membrane protein 19). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in heart adult (RPKM 12.0), cerebellum adult (RPKM 11.2) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Smim19 in Genome Data Viewer
    Location:
    8 A2; 8 11.42 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (22952630..22966850, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (22462614..22476879, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_20903 Neighboring gene mitochondrial ribosomal protein S31 Neighboring gene STARR-seq mESC enhancer starr_20904 Neighboring gene predicted gene, 39140 Neighboring gene STARR-positive B cell enhancer ABC_E9722 Neighboring gene solute carrier family 20, member 2 Neighboring gene STARR-seq mESC enhancer starr_20908 Neighboring gene voltage-dependent anion channel 3 Neighboring gene predicted gene, 30086

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Spermatogonia-dependent expression of testicular genes in mice. Tanaka K, et al. Dev Biol, 2002 Jun 15. PMID 12051830
    2. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
    3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    small integral membrane protein 19
    Names
    UPF0697 protein C8orf40 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012667.3 → NP_001012685.2  small integral membrane protein 19 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC140326
      Consensus CDS
      CCDS52521.1
      UniProtKB/TrEMBL
      E9PUT6
      Related
      ENSMUSP00000131855.2, ENSMUST00000163774.3
      Conserved Domains (1) summary
      pfam15117
      Location:15 → 112
      UPF0697; uncharacterized protein family UPF0697

    2. NM_001146117.2 → NP_001139589.1  small integral membrane protein 19 isoform 2

      See identical proteins and their annotated locations for NP_001139589.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream translational start codon, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, compared to isoform 1.
      Source sequence(s)
      AC140326
      Consensus CDS
      CCDS52520.1
      UniProtKB/Swiss-Prot
      Q80ZU4
      Related
      ENSMUSP00000033935.9, ENSMUST00000033935.16
      Conserved Domains (1) summary
      pfam15117
      Location:10 → 107
      UPF0697; Uncharacterized protein family UPF0697

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      22952630..22966850 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q80ZU4.2 GenPept UniProtKB/Swiss-Prot:Q80ZU4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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