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    Golga7b golgin A7B [ Mus musculus (house mouse) ]

    Gene ID: 71146, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Golga7bprovided by MGI
    Official Full Name
    golgin A7Bprovided by MGI
    Primary source
    MGI:MGI:1918396
    See related
    Ensembl:ENSMUSG00000042532 AllianceGenome:MGI:1918396
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4933417O08Rik
    Summary
    Enables enzyme binding activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in Golgi membrane and plasma membrane. Predicted to be part of palmitoyltransferase complex. Is expressed in cerebral cortex intermediate zone; cerebral cortex subventricular zone; cerebral cortex ventricular layer; and cortical plate. Orthologous to human GOLGA7B (golgin A7 family member B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in cortex adult (RPKM 28.5), frontal lobe adult (RPKM 24.8) and 5 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Golga7b in Genome Data Viewer
    Location:
    19 C3; 19 36.01 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (42236017..42258787)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (42247578..42270348)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E2527 Neighboring gene zinc finger, FYVE domain containing 27 Neighboring gene secreted frizzled-related sequence protein 5 Neighboring gene STARR-seq mESC enhancer starr_46179 Neighboring gene predicted gene, 34347 Neighboring gene microRNA 3085 Neighboring gene cartilage acidic protein 1 Neighboring gene STARR-seq mESC enhancer starr_46182 Neighboring gene STARR-seq mESC enhancer starr_46183 Neighboring gene STARR-seq mESC enhancer starr_46184 Neighboring gene predicted gene, 41848

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. S-acylated Golga7b stabilises DHHC5 at the plasma membrane to regulate cell adhesion. Woodley KT, et al. EMBO Rep, 2019 Oct 4. PMID 31402609, Free PMC Article
    2. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
    3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables enzyme binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of palmitoyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    golgin subfamily A member 7B
    Names
    golgi autoantigen, golgin subfamily a, 7B

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001141983.1 → NP_001135455.1  golgin subfamily A member 7B

      See identical proteins and their annotated locations for NP_001135455.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AI839934, AK016850, BC049116
      Consensus CDS
      CCDS29827.1
      UniProtKB/Swiss-Prot
      A8Y5D0, Q3UTK8, Q9D428
      Related
      ENSMUSP00000112575.2, ENSMUST00000122375.8
      Conserved Domains (1) summary
      pfam10256
      Location:21 → 133
      Erf4; Golgin subfamily A member 7/ERF4 family

    2. NM_027694.2 → NP_081970.1  golgin subfamily A member 7B

      See identical proteins and their annotated locations for NP_081970.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AI839934, AK139354, BC049116
      Consensus CDS
      CCDS29827.1
      UniProtKB/Swiss-Prot
      A8Y5D0, Q3UTK8, Q9D428
      Related
      ENSMUSP00000084362.6, ENSMUST00000087123.6
      Conserved Domains (1) summary
      pfam10256
      Location:21 → 133
      Erf4; Golgin subfamily A member 7/ERF4 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      42236017..42258787
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030251077.1 → XP_030106937.1  golgin subfamily A member 7B isoform X1

      UniProtKB/Swiss-Prot
      A8Y5D0, Q3UTK8, Q9D428
      Conserved Domains (1) summary
      pfam10256
      Location:21 → 133
      Erf4; Golgin subfamily A member 7/ERF4 family

    2. XM_030251076.2 → XP_030106936.1  golgin subfamily A member 7B isoform X1

      UniProtKB/Swiss-Prot
      A8Y5D0, Q3UTK8, Q9D428
      Conserved Domains (1) summary
      pfam10256
      Location:21 → 133
      Erf4; Golgin subfamily A member 7/ERF4 family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D428.1 GenPept UniProtKB/Swiss-Prot:Q9D428

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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