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    Sertm1 serine-rich and transmembrane domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 690333, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Sertm1provided by RGD
    Official Full Name
    serine-rich and transmembrane domain containing 1provided by RGD
    Primary source
    RGD:1597355
    See related
    EnsemblRapid:ENSRNOG00000014046 AllianceGenome:RGD:1597355
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in membrane. Predicted to be active in intracellular membrane-bounded organelle. Orthologous to human SERTM1 (serine rich and transmembrane domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 64.8) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Sertm1 in Genome Data Viewer
    Location:
    2q26
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (141237054..141256669, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (139086905..139106528, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (144303700..144323509, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene regulatory factor X-associated protein Neighboring gene uncharacterized LOC134485734 Neighboring gene uncharacterized LOC134485915 Neighboring gene uncharacterized LOC134485735

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    serine-rich and transmembrane domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109580.1 → NP_001103050.1  serine-rich and transmembrane domain-containing protein 1

      See identical proteins and their annotated locations for NP_001103050.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474003
      UniProtKB/TrEMBL
      A6JVE1, D3ZR22
      Related
      ENSRNOP00000105044.1, ENSRNOT00000130207.1
      Conserved Domains (1) summary
      pfam15872
      Location:1 → 106
      SRTM1; Serine-rich and transmembrane domain-containing protein 1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      141237054..141256669 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006232369.4 → XP_006232431.1  serine-rich and transmembrane domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006232431.1

      UniProtKB/TrEMBL
      A6JVE1, D3ZR22
      Related
      ENSRNOP00000018781.2, ENSRNOT00000018780.5
      Conserved Domains (1) summary
      pfam15872
      Location:1 → 106
      SRTM1; Serine-rich and transmembrane domain-containing protein 1

    2. XM_006232370.4 → XP_006232432.1  serine-rich and transmembrane domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006232432.1

      UniProtKB/TrEMBL
      A6JVE1, D3ZR22
      Related
      ENSRNOP00000104981.1, ENSRNOT00000148004.1
      Conserved Domains (1) summary
      pfam15872
      Location:1 → 106
      SRTM1; Serine-rich and transmembrane domain-containing protein 1

    3. XM_017591119.3 → XP_017446608.1  serine-rich and transmembrane domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A6JVE1, D3ZR22
      Related
      ENSRNOP00000111668.1, ENSRNOT00000159879.1
      Conserved Domains (1) summary
      pfam15872
      Location:1 → 106
      SRTM1; Serine-rich and transmembrane domain-containing protein 1
    Nucleotide Protein Strain
    Heading Accession and Version

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