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    Epb41l1 erythrocyte membrane protein band 4.1 like 1 [ Mus musculus (house mouse) ]

    Gene ID: 13821, updated on 4-Jan-2025

    Summary

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    Official Symbol
    Epb41l1provided by MGI
    Official Full Name
    erythrocyte membrane protein band 4.1 like 1provided by MGI
    Primary source
    MGI:MGI:103010
    See related
    Ensembl:ENSMUSG00000027624 AllianceGenome:MGI:103010
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4.1N; NBL1; Epb4.1l1; mKIAA0338
    Summary
    Predicted to enable signaling receptor binding activity. Involved in regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane. Located in postsynaptic density. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and respiratory system. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 11. Orthologous to human EPB41L1 (erythrocyte membrane protein band 4.1 like 1). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Broad expression in cortex adult (RPKM 33.4), cerebellum adult (RPKM 32.7) and 20 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Epb41l1 in Genome Data Viewer
    Location:
    2 H1; 2 77.39 cM
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (156255918..156385134)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (156417595..156543214)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene 14170 Neighboring gene non-coding RNA activated by DNA damage Neighboring gene ribosomal protein L37a pseudogene Neighboring gene STARR-seq mESC enhancer starr_06170 Neighboring gene STARR-seq mESC enhancer starr_06171 Neighboring gene predicted gene, 33977 Neighboring gene STARR-seq mESC enhancer starr_06172 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:156373177-156373360 Neighboring gene AAR2 splicing factor homolog Neighboring gene predicted gene 14169

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Selective effects of protein 4.1N deficiency on neuroendocrine and reproductive systems. Wang H, et al. Sci Rep, 2020 Oct 12. PMID 33046791, Free PMC Article
    2. Loss of 4.1N in epithelial ovarian cancer results in EMT and matrix-detached cell death resistance. Wang D, et al. Protein Cell, 2021 Feb. PMID 32448967, Free PMC Article
    3. 4.1N binding regions of inositol 1,4,5-trisphosphate receptor type 1. Fukatsu K, et al. Biochem Biophys Res Commun, 2006 Apr 7. PMID 16487933
    4. The function of glutamatergic synapses is not perturbed by severe knockdown of 4.1N and 4.1G expression. Wozny C, et al. J Cell Sci, 2009 Mar 1. PMID 19225127
    5. A novel neuron-enriched homolog of the erythrocyte membrane cytoskeletal protein 4.1. Walensky LD, et al. J Neurosci, 1999 Aug 1. PMID 10414974, Free PMC Article

    See all (55) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Loss of 4.1N in epithelial ovarian cancer results in EMT and matrix-detached cell death resistance.
      Title: Loss of 4.1N in epithelial ovarian cancer results in EMT and matrix-detached cell death resistance.
    2. Selective effects of protein 4.1N deficiency on neuroendocrine and reproductive systems.
      Title: Selective effects of protein 4.1N deficiency on neuroendocrine and reproductive systems.
    3. study describes a previously unknown mechanism that governs activity-dependent GluR1 trafficking, reveals an interaction between AMPAR palmitoylation and phosphorylation, and underscores the importance of 4.1N in AMPAR trafficking and synaptic plasticity.
      Title: Regulation of AMPA receptor extrasynaptic insertion by 4.1N, phosphorylation and palmitoylation.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Gene trapped (1) 
    • Targeted (4)  1 citation

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables signaling receptor binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in actomyosin structure organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cortical actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in postsynaptic density IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in synaptic membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    band 4.1-like protein 1
    Names
    erythrocyte protein band 4.1 like 1
    neuronal protein 4.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001006664.3 → NP_001006665.1  band 4.1-like protein 1 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 3 and 4 all encode isoform a.
      Source sequence(s)
      AL929153, BF464311, CJ113617
      Consensus CDS
      CCDS16966.1
      UniProtKB/TrEMBL
      A2AUK5, B6ZHC9
      Related
      ENSMUSP00000029155.9, ENSMUST00000029155.16
      Conserved Domains (7) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam00373
      Location:183 → 288
      FERM_M; FERM central domain
      pfam04382
      Location:493 → 524
      SAB; SAB domain
      pfam05902
      Location:741 → 866
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 425
      FA; FERM adjacent (FA)
      pfam09379
      Location:101 → 164
      FERM_N; FERM N-terminal domain

    2. NM_001291120.1 → NP_001278049.1  band 4.1-like protein 1 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 3 and 4 all encode isoform a.
      Source sequence(s)
      AK147611, AL929153, BF464311
      Consensus CDS
      CCDS16966.1
      UniProtKB/TrEMBL
      A2AUK5, B6ZHC9
      Related
      ENSMUSP00000099426.4, ENSMUST00000103137.10
      Conserved Domains (7) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam00373
      Location:183 → 288
      FERM_M; FERM central domain
      pfam04382
      Location:493 → 524
      SAB; SAB domain
      pfam05902
      Location:741 → 866
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 425
      FA; FERM adjacent (FA)
      pfam09379
      Location:101 → 164
      FERM_N; FERM N-terminal domain

    3. NM_001291121.1 → NP_001278050.1  band 4.1-like protein 1 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR and lacks an alternate in-frame exon in the central coding region, compared to variant 1. The encoded isoform (c) is shorter than isoform a.
      Source sequence(s)
      AK147611, AL929153, BF464311
      Consensus CDS
      CCDS71169.1
      UniProtKB/TrEMBL
      A2AUK8, B6ZHC9
      Related
      ENSMUSP00000105205.3, ENSMUST00000109577.9
      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:482 → 512
      SAB; SAB domain
      pfam05902
      Location:730 → 854
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    4. NM_001291122.1 → NP_001278051.1  band 4.1-like protein 1 isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR and lacks two alternate in-frame exons in the central coding region, compared to variant 1. The encoded isoform (d) is shorter than isoform a.
      Source sequence(s)
      AK147611, AL929153, BF464311
      UniProtKB/TrEMBL
      B6ZHC9
      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:482 → 512
      SAB; SAB domain
      pfam05902
      Location:594 → 718
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    5. NM_001291123.1 → NP_001278052.1  band 4.1-like protein 1 isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR, and uses an alternate in-frame splice site and lacks two in-frame exons in the central coding region, compared to variant 1. The encoded isoform (e) is shorter than isoform a.
      Source sequence(s)
      AK147272, AK147611, AL929153, BF464311
      Consensus CDS
      CCDS71170.1
      UniProtKB/TrEMBL
      A2AUK7, B6ZHC9
      Related
      ENSMUSP00000105202.2, ENSMUST00000109574.8
      Conserved Domains (7) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam00373
      Location:183 → 288
      FERM_M; FERM central domain
      pfam04382
      Location:481 → 511
      SAB; SAB domain
      pfam05902
      Location:592 → 717
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 425
      FA; FERM adjacent (FA)
      pfam09379
      Location:101 → 164
      FERM_N; FERM N-terminal domain

    6. NM_001368800.1 → NP_001355729.1  band 4.1-like protein 1 isoform f

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) encodes the longest isoform (f).
      Source sequence(s)
      AL928935, AL929153
      Consensus CDS
      CCDS89573.1
      UniProtKB/TrEMBL
      E9PV14
      Related
      ENSMUSP00000121161.4, ENSMUST00000125153.10
      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:492 → 523
      SAB; SAB domain
      pfam05902
      Location:1419 → 1543
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    7. NM_001368801.1 → NP_001355730.1  band 4.1-like protein 1 isoform g

      Status: VALIDATED

      Source sequence(s)
      AL928935, AL929153
      UniProtKB/TrEMBL
      B6ZHC9
      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:486 → 516
      SAB; SAB domain
      pfam05902
      Location:734 → 858
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    8. NM_001368802.1 → NP_001355731.1  band 4.1-like protein 1 isoform h

      Status: VALIDATED

      Source sequence(s)
      AL929153
      UniProtKB/TrEMBL
      B6ZHC9
      Conserved Domains (6) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      PRK08691
      Location:396 → 598
      PRK08691; DNA polymerase III subunits gamma and tau; Validated
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:493 → 523
      SAB; SAB domain
      pfam05902
      Location:741 → 865
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    9. NM_001368803.1 → NP_001355732.1  band 4.1-like protein 1 isoform i

      Status: VALIDATED

      Description
      Transcript Variant: This variant (11), as well as variant 12, encodes isoform i.
      Source sequence(s)
      AL928935, AL929153
      UniProtKB/TrEMBL
      B6ZHC9
      Conserved Domains (6) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      PRK08691
      Location:396 → 599
      PRK08691; DNA polymerase III subunits gamma and tau; Validated
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:494 → 524
      SAB; SAB domain
      pfam05902
      Location:756 → 809
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    10. NM_001368804.1 → NP_001355733.1  band 4.1-like protein 1 isoform i

      Status: VALIDATED

      Description
      Transcript Variant: This variant (12), as well as variant 11, encodes isoform i.
      Source sequence(s)
      AL929153
      UniProtKB/TrEMBL
      B6ZHC9
      Conserved Domains (6) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      PRK08691
      Location:396 → 599
      PRK08691; DNA polymerase III subunits gamma and tau; Validated
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:494 → 524
      SAB; SAB domain
      pfam05902
      Location:756 → 809
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    11. NM_013510.4 → NP_038538.1  band 4.1-like protein 1 isoform a

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform (a). Variants 1, 3 and 4 all encode isoform a.
      Source sequence(s)
      AK147611, AL929153, BF464311
      Consensus CDS
      CCDS16966.1
      UniProtKB/TrEMBL
      A2AUK5, B6ZHC9
      Related
      ENSMUSP00000099425.2, ENSMUST00000103136.8
      Conserved Domains (7) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam00373
      Location:183 → 288
      FERM_M; FERM central domain
      pfam04382
      Location:493 → 524
      SAB; SAB domain
      pfam05902
      Location:741 → 866
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 425
      FA; FERM adjacent (FA)
      pfam09379
      Location:101 → 164
      FERM_N; FERM N-terminal domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      156255918..156385134
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006498711.5 → XP_006498774.1  band 4.1-like protein 1 isoform X4

      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:493 → 524
      SAB; SAB domain
      pfam05902
      Location:1453 → 1577
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 428
      FA; FERM adjacent (FA)

    2. XM_030247282.2 → XP_030103142.1  band 4.1-like protein 1 isoform X14

      UniProtKB/TrEMBL
      B6ZHC9
      Conserved Domains (6) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      PRK08691
      Location:396 → 599
      PRK08691; DNA polymerase III subunits gamma and tau; Validated
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:494 → 524
      SAB; SAB domain
      pfam05902
      Location:756 → 809
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    3. XM_011239275.4 → XP_011237577.1  band 4.1-like protein 1 isoform X5

      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:493 → 523
      SAB; SAB domain
      pfam05902
      Location:1452 → 1576
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    4. XM_030247271.2 → XP_030103131.1  band 4.1-like protein 1 isoform X10

      UniProtKB/TrEMBL
      B6ZHC9
      Conserved Domains (6) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      PRK08691
      Location:396 → 598
      PRK08691; DNA polymerase III subunits gamma and tau; Validated
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:493 → 523
      SAB; SAB domain
      pfam05902
      Location:741 → 865
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    5. XM_030247268.2 → XP_030103128.1  band 4.1-like protein 1 isoform X7

      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:486 → 516
      SAB; SAB domain
      pfam05902
      Location:1445 → 1569
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    6. XM_030247284.2 → XP_030103144.1  band 4.1-like protein 1 isoform X15

      UniProtKB/TrEMBL
      B6ZHC9
      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:486 → 516
      SAB; SAB domain
      pfam05902
      Location:748 → 801
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    7. XM_030247286.2 → XP_030103146.1  band 4.1-like protein 1 isoform X17

      UniProtKB/TrEMBL
      B6ZHC9
      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:486 → 516
      SAB; SAB domain
      pfam05902
      Location:598 → 722
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    8. XM_006498714.4 → XP_006498777.1  band 4.1-like protein 1 isoform X4

      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:493 → 524
      SAB; SAB domain
      pfam05902
      Location:1453 → 1577
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 428
      FA; FERM adjacent (FA)

    9. XM_030247275.2 → XP_030103135.1  band 4.1-like protein 1 isoform X10

      UniProtKB/TrEMBL
      B6ZHC9
      Conserved Domains (6) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      PRK08691
      Location:396 → 598
      PRK08691; DNA polymerase III subunits gamma and tau; Validated
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:493 → 523
      SAB; SAB domain
      pfam05902
      Location:741 → 865
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    10. XM_006498713.4 → XP_006498776.1  band 4.1-like protein 1 isoform X4

      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:493 → 524
      SAB; SAB domain
      pfam05902
      Location:1453 → 1577
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 428
      FA; FERM adjacent (FA)

    11. XM_036158182.1 → XP_036014075.1  band 4.1-like protein 1 isoform X4

      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:493 → 524
      SAB; SAB domain
      pfam05902
      Location:1453 → 1577
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 428
      FA; FERM adjacent (FA)

    12. XM_036158177.1 → XP_036014070.1  band 4.1-like protein 1 isoform X4

      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:493 → 524
      SAB; SAB domain
      pfam05902
      Location:1453 → 1577
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 428
      FA; FERM adjacent (FA)

    13. XM_030247281.2 → XP_030103141.1  band 4.1-like protein 1 isoform X13

      UniProtKB/TrEMBL
      A2AUK8, B6ZHC9
      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:482 → 512
      SAB; SAB domain
      pfam05902
      Location:730 → 854
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    14. XM_030247288.2 → XP_030103148.1  band 4.1-like protein 1 isoform X18

      UniProtKB/TrEMBL
      B6ZHC9
      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:482 → 512
      SAB; SAB domain
      pfam05902
      Location:594 → 718
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    15. XM_011239276.3 → XP_011237578.1  band 4.1-like protein 1 isoform X7

      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:486 → 516
      SAB; SAB domain
      pfam05902
      Location:1445 → 1569
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    16. XM_030247277.2 → XP_030103137.1  band 4.1-like protein 1 isoform X12

      UniProtKB/TrEMBL
      B6ZHC9
      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:486 → 516
      SAB; SAB domain
      pfam05902
      Location:734 → 858
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    17. XM_030247290.2 → XP_030103150.1  band 4.1-like protein 1 isoform X19

      UniProtKB/TrEMBL
      B6ZHC9
      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:474 → 504
      SAB; SAB domain
      pfam05902
      Location:586 → 710
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    18. XM_006498708.4 → XP_006498771.1  band 4.1-like protein 1 isoform X1

      Conserved Domains (5) summary
      smart00295
      Location:111 → 300
      B41; Band 4.1 homologues
      cd13184
      Location:295 → 388
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:506 → 536
      SAB; SAB domain
      pfam05902
      Location:1465 → 1589
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:397 → 438
      FA; FERM adjacent (FA)

    19. XM_011239279.1 → XP_011237581.1  band 4.1-like protein 1 isoform X8

      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:494 → 524
      SAB; SAB domain
      pfam05902
      Location:1467 → 1520
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    20. XM_011239281.1 → XP_011237583.1  band 4.1-like protein 1 isoform X16

      UniProtKB/TrEMBL
      B6ZHC9
      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:494 → 524
      SAB; SAB domain
      pfam05902
      Location:606 → 730
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    21. XM_036158201.1 → XP_036014094.1  band 4.1-like protein 1 isoform X20

      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:493 → 524
      SAB; SAB domain
      pfam05902
      Location:620 → 673
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 428
      FA; FERM adjacent (FA)

    22. XM_011239277.1 → XP_011237579.1  band 4.1-like protein 1 isoform X2

      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:482 → 512
      SAB; SAB domain
      pfam05902
      Location:1441 → 1565
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    23. XM_030247261.1 → XP_030103121.1  band 4.1-like protein 1 isoform X3

      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:481 → 511
      SAB; SAB domain
      pfam05902
      Location:1440 → 1564
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    24. XM_036158191.1 → XP_036014084.1  band 4.1-like protein 1 isoform X9

      UniProtKB/TrEMBL
      B6ZHC9
      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:481 → 511
      SAB; SAB domain
      pfam05902
      Location:729 → 853
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 428
      FA; FERM adjacent (FA)

    25. XM_011239278.1 → XP_011237580.1  band 4.1-like protein 1 isoform X6

      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:474 → 504
      SAB; SAB domain
      pfam05902
      Location:1433 → 1557
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 426
      FA; FERM adjacent (FA)

    26. XM_036158196.1 → XP_036014089.1  band 4.1-like protein 1 isoform X11

      UniProtKB/TrEMBL
      B6ZHC9
      Conserved Domains (5) summary
      smart00295
      Location:99 → 288
      B41; Band 4.1 homologues
      cd13184
      Location:283 → 376
      FERM_C_4_1_family; FERM domain C-lobe of Protein 4.1 family
      pfam04382
      Location:474 → 504
      SAB; SAB domain
      pfam05902
      Location:722 → 846
      4_1_CTD; 4.1 protein C-terminal domain (CTD)
      pfam08736
      Location:385 → 428
      FA; FERM adjacent (FA)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001003815.2: Suppressed sequence

      Description
      NM_001003815.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9Z2H5.2 GenPept UniProtKB/Swiss-Prot:Q9Z2H5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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