U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Slc35e1 solute carrier family 35, member E1 [ Mus musculus (house mouse) ]

    Gene ID: 270066, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Slc35e1provided by MGI
    Official Full Name
    solute carrier family 35, member E1provided by MGI
    Primary source
    MGI:MGI:2142403
    See related
    Ensembl:ENSMUSG00000019731 AllianceGenome:MGI:2142403
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6030458H05
    Summary
    Predicted to enable antiporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including cranial ganglion; craniocervical region bone; incisor; inner ear; and thoracic segment skeleton. Orthologous to human SLC35E1 (solute carrier family 35 member E1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in colon adult (RPKM 24.2), small intestine adult (RPKM 20.6) and 28 other tissues See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Slc35e1 in Genome Data Viewer
    Location:
    8 B3.3; 8 35.08 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (73231839..73246473, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (72477995..72492614, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700030K09 gene Neighboring gene STARR-positive B cell enhancer ABC_E359 Neighboring gene calcium homeostasis endoplasmic reticulum protein Neighboring gene STARR-positive B cell enhancer ABC_E6662 Neighboring gene microRNA 7068 Neighboring gene STARR-positive B cell enhancer ABC_E2267 Neighboring gene uncharacterized LOC102639683 Neighboring gene mediator complex subunit 26 Neighboring gene adaptor protein complex AP-2, mu1 pseudogene

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. SLC35E1 promotes keratinocyte proliferation in psoriasis by regulating zinc homeostasis. Huang T, et al. Cell Death Dis, 2023 Jun 9. PMID 37296095, Free PMC Article
    2. Identification and analysis of genes from the mouse otic vesicle and their association with developmental subprocesses through in situ hybridization. Powles N, et al. Dev Biol, 2004 Apr 1. PMID 15031102
    3. New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules. Das R, et al. J Cell Sci, 2019 Jun 17. PMID 31138677, Free PMC Article
    4. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
    5. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SLC35E1 promotes keratinocyte proliferation in psoriasis by regulating zinc homeostasis.
      Title: SLC35E1 promotes keratinocyte proliferation in psoriasis by regulating zinc homeostasis.
    Submit: New GeneRIF Correction

    Variation

    Go to the top of the page Help

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables antiporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    solute carrier family 35 member E1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177766.3 → NP_808434.2  solute carrier family 35 member E1

      See identical proteins and their annotated locations for NP_808434.2

      Status: VALIDATED

      Source sequence(s)
      AC172623, AK031600, BX513882, CJ166538
      Consensus CDS
      CCDS22415.2
      UniProtKB/Swiss-Prot
      Q8CD26
      Related
      ENSMUSP00000115754.2, ENSMUST00000152080.8
      Conserved Domains (2) summary
      pfam03151
      Location:29 → 333
      TPT; Triose-phosphate Transporter family
      cl23754
      Location:190 → 332
      EamA; EamA-like transporter family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      73231839..73246473 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006509684.3 → XP_006509747.2  solute carrier family 35 member E1 isoform X1

      Conserved Domains (1) summary
      cl26744
      Location:29 → 287
      TPT; Triose-phosphate Transporter family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8CD26.2 GenPept UniProtKB/Swiss-Prot:Q8CD26

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools