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    Kif21a kinesin family member 21A [ Mus musculus (house mouse) ]

    Gene ID: 16564, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Kif21aprovided by MGI
    Official Full Name
    kinesin family member 21Aprovided by MGI
    Primary source
    MGI:MGI:109188
    See related
    Ensembl:ENSMUSG00000022629 AllianceGenome:MGI:109188
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable several functions, including ATP hydrolysis activity; ankyrin repeat binding activity; and plus-end-directed microtubule motor activity. Predicted to be involved in several processes, including cortical microtubule organization; regulation of axon guidance; and regulation of microtubule polymerization or depolymerization. Predicted to be located in axonal growth cone and cytosol. Predicted to be part of kinesin complex. Predicted to be active in cytoplasm and microtubule. Is expressed in several structures, including alimentary system; central nervous system; eye; immune system; and peripheral nervous system. Used to study congenital fibrosis of the extraocular muscles. Human ortholog(s) of this gene implicated in congenital fibrosis of the extraocular muscles 1. Orthologous to human KIF21A (kinesin family member 21A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in CNS E11.5 (RPKM 13.0), CNS E14 (RPKM 12.8) and 21 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Kif21a in Genome Data Viewer
    Location:
    15 E3; 15 45.86 cM
    Exon count:
    41
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (90817478..90934547, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (90933275..91050382, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene sialophorin, pseudogene Neighboring gene predicted gene, 36618 Neighboring gene VISTA enhancer mm1478 Neighboring gene STARR-seq mESC enhancer starr_39489 Neighboring gene predicted gene, 52216 Neighboring gene STARR-seq mESC enhancer starr_39491 Neighboring gene predicted gene, 36710 Neighboring gene karyopherin alpha 7 (importin alpha 8) pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Novel dendritic kinesin sorting identified by different process targeting of two related kinesins: KIF21A and KIF21B. Marszalek JR, et al. J Cell Biol, 1999 May 3. PMID 10225949, Free PMC Article
    2. Nephrotic-syndrome-associated mutation of KANK2 induces pathologic binding competition with physiological interactor KIF21A. Xu Y, et al. J Biol Chem, 2021 Aug. PMID 34274317, Free PMC Article
    3. Three novel mutations in KIF21A highlight the importance of the third coiled-coil stalk domain in the etiology of CFEOM1. Chan WM, et al. BMC Genet, 2007 May 18. PMID 17511870, Free PMC Article
    4. KIF21A-mediated axonal transport and selective endocytosis underlie the polarized targeting of NCKX2. Lee KH, et al. J Neurosci, 2012 Mar 21. PMID 22442075, Free PMC Article
    5. Structural analyses of key features in the KANK1·KIF21A complex yield mechanistic insights into the cross-talk between microtubules and the cell cortex. Weng Z, et al. J Biol Chem, 2018 Jan 5. PMID 29158259, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Nephrotic-syndrome-associated mutation of KANK2 induces pathologic binding competition with physiological interactor KIF21A.
      Title: Nephrotic-syndrome-associated mutation of KANK2 induces pathologic binding competition with physiological interactor KIF21A.
    2. Several key residues (i.e. Thr-1147, Leu-1152, Leu-1153, and Tyr-1154) at the C-terminal half of the KIF21A KBD peptide contact with the hydrophobic patch formed by Tyr-1176, Met-1209, Leu-1210, Leu-1213, and Leu-1248 from KANK1.
      Title: Structural analyses of key features in the KANK1·KIF21A complex yield mechanistic insights into the cross-talk between microtubules and the cell cortex.
    3. The diffuse and widespread expression of KIF21A in the developing human and mouse central and peripheral nervous system as well as in extraocular muscle does not account for the restricted ocular phenotype observed in Congenital fibrosis of the extraocular muscles type 1.
      Title: Spatiotemporal expression pattern of KIF21A during normal embryonic development and in congenital fibrosis of the extraocular muscles type 1 (CFEOM1).
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • mKIAA1708

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ankyrin repeat binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables ankyrin repeat binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule motor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables plus-end-directed microtubule motor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in anterograde axonal transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cortical microtubule organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in microtubule-based movement IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of axon guidance ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of microtubule depolymerization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of microtubule polymerization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in axon cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in axonal growth cone ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in cell cortex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of kinesin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in presynapse IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    kinesin-like protein KIF21A
    Names
    N-5 kinesin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109040.2 → NP_001102510.1  kinesin-like protein KIF21A isoform 1

      See identical proteins and their annotated locations for NP_001102510.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC136003, AK019525, AK049303, AK052821, AK053373, AK147436, AK163536, BC062896, BY714299
      Consensus CDS
      CCDS49708.1
      UniProtKB/Swiss-Prot
      Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1, Q9QXL2
      UniProtKB/TrEMBL
      Q3UHE7
      Related
      ENSMUSP00000085985.6, ENSMUST00000088614.13
      Conserved Domains (7) summary
      smart00129
      Location:9 → 378
      KISc; Kinesin motor, catalytic domain. ATPase
      COG2319
      Location:1343 → 1650
      WD40; WD40 repeat [General function prediction only]
      COG2882
      Location:670 → 806
      FliJ; Flagellar biosynthesis chaperone FliJ [Cell motility]
      cd00200
      Location:1337 → 1650
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:8 → 372
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      pfam02050
      Location:664 → 801
      FliJ; Flagellar FliJ protein
      sd00039
      Location:1388 → 1447
      7WD40; WD40 repeat [structural motif]

    2. NM_001109041.2 → NP_001102511.1  kinesin-like protein KIF21A isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.
      Source sequence(s)
      AC136003, AK019525, AK052821, AK053373, AK147436, BC060698, BY714299
      Consensus CDS
      CCDS49707.1
      UniProtKB/TrEMBL
      F8WGN6, Q3UHE7
      Related
      ENSMUSP00000066911.9, ENSMUST00000067205.16
      Conserved Domains (7) summary
      smart00129
      Location:9 → 378
      KISc; Kinesin motor, catalytic domain. ATPase
      COG2319
      Location:1299 → 1606
      WD40; WD40 repeat [General function prediction only]
      COG2882
      Location:657 → 793
      FliJ; Flagellar biosynthesis chaperone FliJ [Cell motility]
      cd00200
      Location:1293 → 1606
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:8 → 372
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      pfam02050
      Location:651 → 788
      FliJ; Flagellar FliJ protein
      sd00039
      Location:1344 → 1403
      7WD40; WD40 repeat [structural motif]

    3. NM_001109042.2 → NP_001102512.1  kinesin-like protein KIF21A isoform 4

      See identical proteins and their annotated locations for NP_001102512.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks four alternate exons in the central coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (4) is shorter, compared to isoform 1.
      Source sequence(s)
      AC136003, AK019525, AK052821, AK053373, BC060698, BY714299
      Consensus CDS
      CCDS49706.1
      UniProtKB/TrEMBL
      Q3UHE7
      Related
      ENSMUSP00000104910.3, ENSMUST00000109287.4
      Conserved Domains (7) summary
      smart00129
      Location:9 → 378
      KISc; Kinesin motor, catalytic domain. ATPase
      COG2319
      Location:1238 → 1545
      WD40; WD40 repeat [General function prediction only]
      COG2882
      Location:657 → 793
      FliJ; Flagellar biosynthesis chaperone FliJ [Cell motility]
      cd00200
      Location:1232 → 1545
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:8 → 372
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      pfam02050
      Location:651 → 788
      FliJ; Flagellar FliJ protein
      sd00039
      Location:1283 → 1342
      7WD40; WD40 repeat [structural motif]

    4. NM_001358050.1 → NP_001344979.1  kinesin-like protein KIF21A isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) lacks alternate exons in the central coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (5) is shorter, compared to isoform 1.
      Source sequence(s)
      AC113102, AC136003
      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      cd00200
      Location:1268 → 1581
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:8 → 372
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1319 → 1378
      7WD40; WD40 repeat [structural motif]
      cl25732
      Location:633 → 827
      SMC_N; RecF/RecN/SMC N terminal domain
      cl26252
      Location:680 → 1102
      AAA_13; AAA domain

    5. NM_001411306.1 → NP_001398235.1  kinesin-like protein KIF21A isoform 6

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) lacks alternate exons in the central coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (6) is shorter, compared to isoform 1.
      Source sequence(s)
      AC113102, AC136003
      UniProtKB/TrEMBL
      Q3UHE7

    6. NM_001411307.1 → NP_001398236.1  kinesin-like protein KIF21A isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) lacks alternate exons in the central coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (7) is shorter, compared to isoform 1.
      Source sequence(s)
      AC113102, AC136003
      UniProtKB/TrEMBL
      Q3UHE7

    7. NM_016705.4 → NP_057914.2  kinesin-like protein KIF21A isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks four alternate exons in the central coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (3) is shorter, compared to isoform 1.
      Source sequence(s)
      AC136003, AK019525, AK052821, AK053373, AK147436, BC060698, BY714299
      Consensus CDS
      CCDS37179.1
      UniProtKB/TrEMBL
      Q3UHE7
      Related
      ENSMUSP00000104911.3, ENSMUST00000109288.9
      Conserved Domains (7) summary
      smart00129
      Location:9 → 378
      KISc; Kinesin motor, catalytic domain. ATPase
      COG2319
      Location:1244 → 1551
      WD40; WD40 repeat [General function prediction only]
      COG2882
      Location:657 → 793
      FliJ; Flagellar biosynthesis chaperone FliJ [Cell motility]
      cd00200
      Location:1238 → 1551
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:8 → 372
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      pfam02050
      Location:651 → 788
      FliJ; Flagellar FliJ protein
      sd00039
      Location:1289 → 1348
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      90817478..90934547 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017316478.3 → XP_017171967.1  kinesin-like protein KIF21A isoform X41

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      TIGR00606
      Location:568 → 871
      rad50
      COG1196
      Location:284 → 682
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1245 → 1558
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:1296 → 1355
      7WD40; WD40 repeat [structural motif]
      cl22853
      Location:1 → 275
      Motor_domain; Myosin and Kinesin motor domain

    2. XM_036159185.1 → XP_036015078.1  kinesin-like protein KIF21A isoform X33

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (6) summary
      TIGR00606
      Location:665 → 968
      rad50
      COG1196
      Location:381 → 779
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1263 → 1576
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:8 → 372
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1314 → 1373
      7WD40; WD40 repeat [structural motif]
      cd22263
      Location:938 → 1019
      Rcc_KIF21A; regulatory coiled-coil domain found in kinesin-like protein KIF21A

    3. XM_017316445.3 → XP_017171934.1  kinesin-like protein KIF21A isoform X5

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      TIGR00606
      Location:665 → 968
      rad50
      COG1196
      Location:345 → 1102
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1342 → 1655
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:8 → 372
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1393 → 1452
      7WD40; WD40 repeat [structural motif]

    4. XM_036159190.1 → XP_036015083.1  kinesin-like protein KIF21A isoform X43

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (6) summary
      COG1196
      Location:633 → 827
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1225 → 1538
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:8 → 372
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1276 → 1335
      7WD40; WD40 repeat [structural motif]
      pfam15921
      Location:349 → 956
      CCDC158; Coiled-coil domain-containing protein 158
      cd22263
      Location:925 → 1006
      Rcc_KIF21A; regulatory coiled-coil domain found in kinesin-like protein KIF21A

    5. XM_036159188.1 → XP_036015081.1  kinesin-like protein KIF21A isoform X38

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (6) summary
      COG1196
      Location:633 → 827
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1250 → 1563
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:8 → 372
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1301 → 1360
      7WD40; WD40 repeat [structural motif]
      pfam15921
      Location:349 → 956
      CCDC158; Coiled-coil domain-containing protein 158
      cd22263
      Location:925 → 1006
      Rcc_KIF21A; regulatory coiled-coil domain found in kinesin-like protein KIF21A

    6. XM_036159181.1 → XP_036015074.1  kinesin-like protein KIF21A isoform X24

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (6) summary
      COG1196
      Location:633 → 827
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1286 → 1599
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:8 → 372
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1337 → 1396
      7WD40; WD40 repeat [structural motif]
      pfam10174
      Location:364 → 825
      Cast; RIM-binding protein of the cytomatrix active zone
      cd22263
      Location:925 → 1006
      Rcc_KIF21A; regulatory coiled-coil domain found in kinesin-like protein KIF21A

    7. XM_006520495.5 → XP_006520558.1  kinesin-like protein KIF21A isoform X11

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      pfam05483
      Location:389 → 1027
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      COG1196
      Location:633 → 827
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1329 → 1642
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:8 → 372
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1380 → 1439
      7WD40; WD40 repeat [structural motif]

    8. XM_017316476.2 → XP_017171965.1  kinesin-like protein KIF21A isoform X39

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      pfam05483
      Location:397 → 1035
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      COG1196
      Location:641 → 835
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1246 → 1559
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1297 → 1356
      7WD40; WD40 repeat [structural motif]

    9. XM_017316462.2 → XP_017171951.1  kinesin-like protein KIF21A isoform X26

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      pfam05483
      Location:397 → 1035
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      COG1196
      Location:641 → 835
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1282 → 1595
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1333 → 1392
      7WD40; WD40 repeat [structural motif]

    10. XM_017316452.2 → XP_017171941.1  kinesin-like protein KIF21A isoform X14

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      pfam05483
      Location:397 → 1035
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      COG1196
      Location:641 → 835
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1312 → 1625
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1363 → 1422
      7WD40; WD40 repeat [structural motif]

    11. XM_036159176.1 → XP_036015069.1  kinesin-like protein KIF21A isoform X10

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (6) summary
      COG1196
      Location:641 → 835
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1330 → 1643
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1381 → 1440
      7WD40; WD40 repeat [structural motif]
      pfam10174
      Location:372 → 833
      Cast; RIM-binding protein of the cytomatrix active zone
      cd22263
      Location:933 → 1014
      Rcc_KIF21A; regulatory coiled-coil domain found in kinesin-like protein KIF21A

    12. XM_036159187.1 → XP_036015080.1  kinesin-like protein KIF21A isoform X35

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (6) summary
      COG1196
      Location:641 → 835
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1257 → 1570
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1308 → 1367
      7WD40; WD40 repeat [structural motif]
      pfam15921
      Location:357 → 964
      CCDC158; Coiled-coil domain-containing protein 158
      cd22263
      Location:933 → 1014
      Rcc_KIF21A; regulatory coiled-coil domain found in kinesin-like protein KIF21A

    13. XM_036159186.1 → XP_036015079.1  kinesin-like protein KIF21A isoform X34

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (6) summary
      COG1196
      Location:641 → 835
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1258 → 1571
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1309 → 1368
      7WD40; WD40 repeat [structural motif]
      pfam15921
      Location:357 → 964
      CCDC158; Coiled-coil domain-containing protein 158
      cd22263
      Location:933 → 1014
      Rcc_KIF21A; regulatory coiled-coil domain found in kinesin-like protein KIF21A

    14. XM_017316461.2 → XP_017171950.1  kinesin-like protein KIF21A isoform X25

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (4) summary
      pfam05483
      Location:397 → 1035
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      cd00200
      Location:1283 → 1596
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1334 → 1393
      7WD40; WD40 repeat [structural motif]

    15. XM_017316456.2 → XP_017171945.1  kinesin-like protein KIF21A isoform X18

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (4) summary
      pfam05483
      Location:397 → 1035
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      cd00200
      Location:1301 → 1614
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1352 → 1411
      7WD40; WD40 repeat [structural motif]

    16. XM_036159180.1 → XP_036015073.1  kinesin-like protein KIF21A isoform X23

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (6) summary
      COG1196
      Location:641 → 835
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1289 → 1602
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1340 → 1399
      7WD40; WD40 repeat [structural motif]
      pfam15921
      Location:357 → 964
      CCDC158; Coiled-coil domain-containing protein 158
      cd22263
      Location:933 → 1014
      Rcc_KIF21A; regulatory coiled-coil domain found in kinesin-like protein KIF21A

    17. XM_036159179.1 → XP_036015072.1  kinesin-like protein KIF21A isoform X21

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (6) summary
      COG1196
      Location:641 → 835
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1294 → 1607
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1345 → 1404
      7WD40; WD40 repeat [structural motif]
      pfam15921
      Location:357 → 964
      CCDC158; Coiled-coil domain-containing protein 158
      cd22263
      Location:933 → 1014
      Rcc_KIF21A; regulatory coiled-coil domain found in kinesin-like protein KIF21A

    18. XM_017316449.2 → XP_017171938.1  kinesin-like protein KIF21A isoform X12

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      pfam05483
      Location:397 → 1035
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      COG1196
      Location:641 → 835
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1319 → 1632
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1370 → 1429
      7WD40; WD40 repeat [structural motif]

    19. XM_017316447.2 → XP_017171936.1  kinesin-like protein KIF21A isoform X8

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      pfam05483
      Location:397 → 1035
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      COG1196
      Location:641 → 835
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1336 → 1649
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1387 → 1446
      7WD40; WD40 repeat [structural motif]

    20. XM_017316446.2 → XP_017171935.1  kinesin-like protein KIF21A isoform X7

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      pfam05483
      Location:397 → 1035
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      COG1196
      Location:641 → 835
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1337 → 1650
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1388 → 1447
      7WD40; WD40 repeat [structural motif]

    21. XM_036159184.1 → XP_036015077.1  kinesin-like protein KIF21A isoform X32

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (6) summary
      TIGR00606
      Location:673 → 976
      rad50
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1264 → 1577
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1315 → 1374
      7WD40; WD40 repeat [structural motif]
      cd22263
      Location:946 → 1027
      Rcc_KIF21A; regulatory coiled-coil domain found in kinesin-like protein KIF21A

    22. XM_017316458.2 → XP_017171947.1  kinesin-like protein KIF21A isoform X20

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      COG0419
      Location:650 → 1110
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1295 → 1608
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1346 → 1405
      7WD40; WD40 repeat [structural motif]

    23. XM_036159178.1 → XP_036015071.1  kinesin-like protein KIF21A isoform X19

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (6) summary
      TIGR00606
      Location:673 → 976
      rad50
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1300 → 1613
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1351 → 1410
      7WD40; WD40 repeat [structural motif]
      cd22263
      Location:946 → 1027
      Rcc_KIF21A; regulatory coiled-coil domain found in kinesin-like protein KIF21A

    24. XM_036159174.1 → XP_036015067.1  kinesin-like protein KIF21A isoform X6

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (6) summary
      TIGR00606
      Location:673 → 976
      rad50
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1338 → 1651
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1389 → 1448
      7WD40; WD40 repeat [structural motif]
      cd22263
      Location:946 → 1027
      Rcc_KIF21A; regulatory coiled-coil domain found in kinesin-like protein KIF21A

    25. XM_017316444.2 → XP_017171933.1  kinesin-like protein KIF21A isoform X4

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      COG0419
      Location:650 → 1110
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1343 → 1656
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1394 → 1453
      7WD40; WD40 repeat [structural motif]

    26. XM_017316475.2 → XP_017171964.1  kinesin-like protein KIF21A isoform X37

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      COG0419
      Location:650 → 1110
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1253 → 1566
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1304 → 1363
      7WD40; WD40 repeat [structural motif]

    27. XM_017316468.2 → XP_017171957.1  kinesin-like protein KIF21A isoform X31

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      COG0419
      Location:650 → 1110
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1266 → 1579
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1317 → 1376
      7WD40; WD40 repeat [structural motif]

    28. XM_017316465.2 → XP_017171954.1  kinesin-like protein KIF21A isoform X30

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      COG0419
      Location:650 → 1110
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1270 → 1583
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1321 → 1380
      7WD40; WD40 repeat [structural motif]

    29. XM_017316464.2 → XP_017171953.1  kinesin-like protein KIF21A isoform X29

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      COG0419
      Location:650 → 1110
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1271 → 1584
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1322 → 1381
      7WD40; WD40 repeat [structural motif]

    30. XM_017316450.2 → XP_017171939.1  kinesin-like protein KIF21A isoform X13

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      COG0419
      Location:650 → 1110
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1314 → 1627
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1365 → 1424
      7WD40; WD40 repeat [structural motif]

    31. XM_017316455.2 → XP_017171944.1  kinesin-like protein KIF21A isoform X17

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      COG0419
      Location:650 → 1110
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1302 → 1615
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1353 → 1412
      7WD40; WD40 repeat [structural motif]

    32. XM_017316454.2 → XP_017171943.1  kinesin-like protein KIF21A isoform X16

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      COG0419
      Location:650 → 1110
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1306 → 1619
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1357 → 1416
      7WD40; WD40 repeat [structural motif]

    33. XM_017316453.2 → XP_017171942.1  kinesin-like protein KIF21A isoform X15

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      COG0419
      Location:650 → 1110
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1307 → 1620
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1358 → 1417
      7WD40; WD40 repeat [structural motif]

    34. XM_017316448.2 → XP_017171937.1  kinesin-like protein KIF21A isoform X9

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      COG0419
      Location:650 → 1110
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1332 → 1645
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1383 → 1442
      7WD40; WD40 repeat [structural motif]

    35. XM_017316443.2 → XP_017171932.1  kinesin-like protein KIF21A isoform X3

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      COG0419
      Location:650 → 1110
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1345 → 1658
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1396 → 1455
      7WD40; WD40 repeat [structural motif]

    36. XM_017316442.2 → XP_017171931.1  kinesin-like protein KIF21A isoform X2

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      COG0419
      Location:650 → 1110
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1349 → 1662
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1400 → 1459
      7WD40; WD40 repeat [structural motif]

    37. XM_017316441.2 → XP_017171930.1  kinesin-like protein KIF21A isoform X1

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      COG0419
      Location:650 → 1110
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1350 → 1663
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1401 → 1460
      7WD40; WD40 repeat [structural motif]

    38. XM_017316474.3 → XP_017171963.1  kinesin-like protein KIF21A isoform X36

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (4) summary
      pfam05483
      Location:397 → 1035
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      cd00200
      Location:1253 → 1566
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1304 → 1363
      7WD40; WD40 repeat [structural motif]

    39. XM_017316479.3 → XP_017171968.1  kinesin-like protein KIF21A isoform X42

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (4) summary
      pfam05483
      Location:397 → 1035
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      cd00200
      Location:1240 → 1553
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1291 → 1350
      7WD40; WD40 repeat [structural motif]

    40. XM_017316460.3 → XP_017171949.1  kinesin-like protein KIF21A isoform X22

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      COG0419
      Location:650 → 1110
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG1196
      Location:389 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1289 → 1602
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1340 → 1399
      7WD40; WD40 repeat [structural motif]

    41. XM_017316463.3 → XP_017171952.1  kinesin-like protein KIF21A isoform X28

      UniProtKB/TrEMBL
      Q3UHE7
      Conserved Domains (5) summary
      pfam05483
      Location:397 → 1035
      SCP-1; Synaptonemal complex protein 1 (SCP-1)
      COG1196
      Location:641 → 835
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00200
      Location:1276 → 1589
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cd01372
      Location:23 → 380
      KISc_KIF4; Kinesin motor domain, KIF4-like subfamily
      sd00039
      Location:1327 → 1386
      7WD40; WD40 repeat [structural motif]

    RNA

    1. XR_004938801.1 RNA Sequence

    2. XR_004938800.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9QXL2.2 GenPept UniProtKB/Swiss-Prot:Q9QXL2

    Gene LinkOut

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