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    Rundc1 RUN domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 217201, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Rundc1provided by MGI
    Official Full Name
    RUN domain containing 1provided by MGI
    Primary source
    MGI:MGI:2144506
    See related
    Ensembl:ENSMUSG00000035007 AllianceGenome:MGI:2144506
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D930024B17
    Summary
    Acts upstream of or within in utero embryonic development. Is expressed in central nervous system and retina. Orthologous to human RUNDC1 (RUN domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 12.9), colon adult (RPKM 12.1) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Rundc1 in Genome Data Viewer
    Location:
    11 D; 11 65.0 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (101315910..101326492)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (101425085..101435666)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene alanyl-tRNA synthetase domain containing 1 Neighboring gene prostaglandin E synthase 3 like Neighboring gene microRNA 6929 Neighboring gene STARR-positive B cell enhancer ABC_E596 Neighboring gene STARR-positive B cell enhancer ABC_E1431 Neighboring gene ribosomal protein L27 Neighboring gene STARR-positive B cell enhancer ABC_E7067 Neighboring gene STARR-seq mESC enhancer starr_30763 Neighboring gene interferon-induced protein 35

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Knockout mice with pituitary malformations help identify human cases of hypopituitarism. Martinez-Mayer J, et al. Genome Med, 2024 May 31. PMID 38822427, Free PMC Article
    2. A staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5). Geyer SH, et al. J Anat, 2017 May. PMID 28185240, Free PMC Article
    3. Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice. Wilson R, et al. Wellcome Open Res, 2016. PMID 27996060, Free PMC Article
    4. Placentation defects are highly prevalent in embryonic lethal mouse mutants. Perez-Garcia V, et al. Nature, 2018 Mar 22. PMID 29539633, Free PMC Article
    5. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC141375, MGC141376

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within in utero embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RUN domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172566.4 → NP_766154.2  RUN domain-containing protein 1

      See identical proteins and their annotated locations for NP_766154.2

      Status: VALIDATED

      Source sequence(s)
      AK086362, AW125546, BC119592
      Consensus CDS
      CCDS25469.1
      UniProtKB/Swiss-Prot
      Q0VDN6, Q0VDN7, Q3U072, Q8C3C0
      Related
      ENSMUSP00000042151.6, ENSMUST00000040561.6
      Conserved Domains (1) summary
      cl02689
      Location:431 → 582
      RUN; RUN domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      101315910..101326492
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006533035.5 → XP_006533098.1  RUN domain-containing protein 1 isoform X1

      Conserved Domains (2) summary
      TIGR04523
      Location:167 → 291
      Mplasa_alph_rch; helix-rich Mycoplasma protein
      cl02689
      Location:433 → 584
      RUN; RUN domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0VDN7.1 GenPept UniProtKB/Swiss-Prot:Q0VDN7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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