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    Adck5 aarF domain containing kinase 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362943, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Adck5provided by RGD
    Official Full Name
    aarF domain containing kinase 5provided by RGD
    Primary source
    RGD:1305504
    See related
    EnsemblRapid:ENSRNOG00000030334 AllianceGenome:RGD:1305504
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in membrane and mitochondrion. Orthologous to human ADCK5 (aarF domain containing kinase 5). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Adrenal (RPKM 267.9), Liver (RPKM 139.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Adck5 in Genome Data Viewer
    Location:
    7q34
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (110182275..110200088)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (108301623..108319439)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (117643976..117661789)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479929 Neighboring gene uncharacterized LOC134479928 Neighboring gene cleavage and polyadenylation specific factor 1 Neighboring gene solute carrier family 39 member 4 Neighboring gene VPS28 subunit of ESCRT-I

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article
    2. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC112651, MGC188570

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized aarF domain-containing protein kinase 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135798.2 → NP_001129270.1  uncharacterized aarF domain-containing protein kinase 5

      See identical proteins and their annotated locations for NP_001129270.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/TrEMBL
      A6HSB0, G3V9I7
      Related
      ENSRNOP00000048745.5, ENSRNOT00000044893.6
      Conserved Domains (2) summary
      COG0661
      Location:128 → 499
      AarF; Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family [Coenzyme transport and metabolism, Signal transduction mechanisms]
      cd13969
      Location:169 → 420
      ADCK1-like; aarF domain containing kinase 1 and similar proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      110182275..110200088
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039079556.2 → XP_038935484.1  uncharacterized aarF domain-containing protein kinase 5 isoform X1

      Conserved Domains (1) summary
      cd13969
      Location:62 → 313
      ADCK1-like; aarF domain containing kinase 1 and similar proteins

    2. XM_039079558.2 → XP_038935486.1  uncharacterized aarF domain-containing protein kinase 5 isoform X2

      Conserved Domains (1) summary
      cl21453
      Location:1 → 166
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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