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    ZNF836 zinc finger protein 836 [ Homo sapiens (human) ]

    Gene ID: 162962, updated on 10-Dec-2024

    Summary

    Official Symbol
    ZNF836provided by HGNC
    Official Full Name
    zinc finger protein 836provided by HGNC
    Primary source
    HGNC:HGNC:34333
    See related
    Ensembl:ENSG00000196267 AllianceGenome:HGNC:34333
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in adrenal (RPKM 5.5), ovary (RPKM 1.8) and 24 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See ZNF836 in Genome Data Viewer
    Location:
    19q13.41
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (52154107..52171621, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (55241321..55258831, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (52657360..52674874, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 616 Neighboring gene uncharacterized LOC124904799 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15036 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10991 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10992 Neighboring gene ribosomal protein L37 pseudogene 23 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15037 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10993 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:52691895-52692862 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:52692863-52693830 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15042 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:52695753-52696253 Neighboring gene protein phosphatase 2 scaffold subunit Aalpha Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr19:52724813-52726012 Neighboring gene uncharacterized LOC105372449 Neighboring gene microRNA 6801 Neighboring gene vomeronasal 1 receptor 99 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102657.3NP_001096127.1  zinc finger protein 836

      See identical proteins and their annotated locations for NP_001096127.1

      Status: VALIDATED

      Source sequence(s)
      AC010320, AC011468
      Consensus CDS
      CCDS46162.1
      UniProtKB/Swiss-Prot
      Q6ZNA1
      Related
      ENSP00000507838.1, ENST00000682614.1
      Conserved Domains (6) summary
      smart00349
      Location:848
      KRAB; krueppel associated box
      COG5048
      Location:272648
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:304324
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:696714
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:847
      KRAB; KRAB box
      pfam13465
      Location:372397
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      52154107..52171621 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011526559.4XP_011524861.1  zinc finger protein 836 isoform X1

      See identical proteins and their annotated locations for XP_011524861.1

      UniProtKB/Swiss-Prot
      Q6ZNA1
      Conserved Domains (6) summary
      smart00349
      Location:848
      KRAB; krueppel associated box
      COG5048
      Location:272648
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:304324
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:696714
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:847
      KRAB; KRAB box
      pfam13465
      Location:372397
      zf-H2C2_2; Zinc-finger double domain
    2. XM_011526558.4XP_011524860.1  zinc finger protein 836 isoform X1

      See identical proteins and their annotated locations for XP_011524860.1

      UniProtKB/Swiss-Prot
      Q6ZNA1
      Conserved Domains (6) summary
      smart00349
      Location:848
      KRAB; krueppel associated box
      COG5048
      Location:272648
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:304324
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:696714
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:847
      KRAB; KRAB box
      pfam13465
      Location:372397
      zf-H2C2_2; Zinc-finger double domain

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      55241321..55258831 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054320022.1XP_054175997.1  zinc finger protein 836 isoform X1

      UniProtKB/Swiss-Prot
      Q6ZNA1
    2. XM_054320021.1XP_054175996.1  zinc finger protein 836 isoform X1

      UniProtKB/Swiss-Prot
      Q6ZNA1