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    Ndufa11 NADH:ubiquinone oxidoreductase subunit A11 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 301123, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ndufa11provided by RGD
    Official Full Name
    NADH:ubiquinone oxidoreductase subunit A11provided by RGD
    Primary source
    RGD:1303292
    See related
    EnsemblRapid:ENSRNOG00000048320 AllianceGenome:RGD:1303292
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Human ortholog(s) of this gene implicated in communication disorder and nuclear type mitochondrial complex I deficiency 14. Orthologous to human NDUFA11 (NADH:ubiquinone oxidoreductase subunit A11). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 2764.8), Muscle (RPKM 1817.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Ndufa11 in Genome Data Viewer
    Location:
    9q11
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (1637614..1641673)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (1550487..1554546)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (10334104..10338163, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene RAN binding protein 3 Neighboring gene calcyphosine Neighboring gene vimentin-type intermediate filament associated coiled-coil protein Neighboring gene fucosyltransferase 4, pseudogene 1 Neighboring gene neurturin

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in mitochondrial respiratory chain complex I assembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitochondrial respiratory chain complex I assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrial respiratory chain complex I assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of respiratory chain complex I IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of respiratory chain complex I IEA
    Inferred from Electronic Annotation
    more info
     
    part_of respiratory chain complex I ISO
    Inferred from Sequence Orthology
    more info
     
    part_of respiratory chain complex I ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
    Names
    CI-B14.7
    NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 11
    NADH-ubiquinone oxidoreductase subunit B14.7
    complex I-B14.7
    NP_997682.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212517.1NP_997682.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11

      See identical proteins and their annotated locations for NP_997682.1

      Status: PROVISIONAL

      Source sequence(s)
      AY272059
      UniProtKB/Swiss-Prot
      Q80W89
      UniProtKB/TrEMBL
      A0A8L2QX46, A6KQV2
      Related
      ENSRNOP00000064246.2, ENSRNOT00000070862.4
      Conserved Domains (1) summary
      pfam02466
      Location:27125
      Tim17; Tim17/Tim22/Tim23/Pmp24 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      1637614..1641673
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)