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    LINC01816 long intergenic non-protein coding RNA 1816 [ Homo sapiens (human) ]

    Gene ID: 100133985, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC01816provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 1816provided by HGNC
    Primary source
    HGNC:HGNC:52621
    See related
    Ensembl:ENSG00000231327 AllianceGenome:HGNC:52621
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Broad expression in kidney (RPKM 1.5), brain (RPKM 1.2) and 17 other tissues See more
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    Genomic context

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    See LINC01816 in Genome Data Viewer
    Location:
    2p13.3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (70124036..70125316, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (70135778..70137058, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (70351168..70352448, complement)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124906022 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15989 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15990 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15991 Neighboring gene mitochondrial ribosomal protein L36 pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15992 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15993 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15994 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:70350131-70350936 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:70350937-70351742 Neighboring gene Sharpr-MPRA regulatory region 3961 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15995 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15996 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15997 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70365403-70365944 Neighboring gene Sharpr-MPRA regulatory region 12614 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:70368111-70368650 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11607 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15998 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15999 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11608 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16000 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:70376065-70376594 Neighboring gene chromosome 2 open reading frame 42 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16001 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16002 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16003 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16004 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:70418013-70418598 Neighboring gene TIA1 cytotoxic granule associated RNA binding protein Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:70474526-70475341 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:70475342-70476156

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. LINC01816 promotes the migration, invasion and epithelial‑mesenchymal transition of thyroid carcinoma cells by sponging miR‑34c‑5p and regulating CRABP2 expression levels. Zhao H, et al. Oncol Rep, 2021 May. PMID 33786631, Free PMC Article
    2. Differentially Expressed lncRNAs in Gastric Cancer Patients: A Potential Biomarker for Gastric Cancer Prognosis. Tian X, et al. J Cancer, 2017. PMID 28900495, Free PMC Article
    3. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. Navarini AA, et al. Nat Commun, 2014 Jun 13. PMID 24927181
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LINC01816 promotes the migration, invasion and epithelialmesenchymal transition of thyroid carcinoma cells by sponging miR34c5p and regulating CRABP2 expression levels.
      Title: LINC01816 promotes the migration, invasion and epithelial‑mesenchymal transition of thyroid carcinoma cells by sponging miR‑34c‑5p and regulating CRABP2 expression levels.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Clone Names

    • AC016700.5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_024444.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      BC015412
      Related
      ENST00000414141.3

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      70124036..70125316 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      70135778..70137058 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials