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    LINC00327 long intergenic non-protein coding RNA 327 [ Homo sapiens (human) ]

    Gene ID: 100506697, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC00327provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 327provided by HGNC
    Primary source
    HGNC:HGNC:42009
    See related
    Ensembl:ENSG00000232977 AllianceGenome:HGNC:42009
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    NCRNA00327
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See LINC00327 in Genome Data Viewer
    Location:
    13q12.12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (23469512..23487464)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (22676313..22693937)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (24043651..24061603)

    Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene sacsin molecular chaperone Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5171 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5172 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7452 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7453 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7454 Neighboring gene ribosomal protein lateral stalk subunit P1 pseudogene 13 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr13:24007093-24007660 Neighboring gene SACS antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:24014794-24015294 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:24015295-24015795 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr13:24022765-24023604 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7455 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_32713 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5173 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7456 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:24066632-24067132 Neighboring gene uncharacterized LOC124903135 Neighboring gene NANOG hESC enhancer GRCh37_chr13:24081975-24082502 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr13:24100455-24101050 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7457 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7458 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:24141962-24142474 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:24142475-24142986 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_32734 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7459 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5174 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5175 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_32745 Neighboring gene TNF receptor superfamily member 19 Neighboring gene H3K27ac hESC enhancer GRCh37_chr13:24192537-24193038 Neighboring gene H3K27ac hESC enhancer GRCh37_chr13:24195169-24195668 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:24205756-24206564 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:24206565-24207373 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:24213321-24213822 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:24228053-24228554 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7460

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study. Sung YJ, et al. Am J Hypertens, 2015 Mar. PMID 25189868, Free PMC Article
    2. Novel associations for hypothyroidism include known autoimmune risk loci. Eriksson N, et al. PLoS One, 2012. PMID 22493691, Free PMC Article
    3. Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution. Cheng J, et al. Science, 2005 May 20. PMID 15790807

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Gene-Smoking Interactions Identify Several Novel Blood Pressure Loci in the Framingham Heart Study.
    EBI GWAS Catalog
    Novel associations for hypothyroidism include known autoimmune risk loci.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_038995.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL354815, AL833146, BX098743
      Related
      ENST00000443778.3

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

      Range
      23469512..23487464
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060937.1 Alternate T2T-CHM13v2.0

      Range
      22676313..22693937
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Research Materials