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    ZNF433-AS1 ZNF433 and ZNF878 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 101928464, updated on 10-Dec-2024

    Summary

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    Official Symbol
    ZNF433-AS1provided by HGNC
    Official Full Name
    ZNF433 and ZNF878 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:53776
    See related
    Ensembl:ENSG00000219665 AllianceGenome:HGNC:53776
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Broad expression in testis (RPKM 2.1), bone marrow (RPKM 1.2) and 24 other tissues See more
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    Genomic context

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    See ZNF433-AS1 in Genome Data Viewer
    Location:
    19p13.2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (11987617..12046275)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (12115811..12174482)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (12098432..12157090)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 69 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:12074983-12075936 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10136 Neighboring gene vomeronasal 2 receptor 21 pseudogene Neighboring gene zinc finger protein 763 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:12098284-12099226 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:12099227-12100168 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14042 Neighboring gene RNA, 5S ribosomal pseudogene 464 Neighboring gene zinc finger protein 433 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10138 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10137 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10139 Neighboring gene RNA, 5S ribosomal pseudogene 465 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10140 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:12163610-12164115 Neighboring gene zinc finger protein 878 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14043 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10141 Neighboring gene RNA, 5S ribosomal pseudogene 466 Neighboring gene zinc finger protein 844 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10142 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10143 Neighboring gene ribosomal L24 domain containing 1 pseudogene 8 Neighboring gene zinc finger family member 788, pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis. Nischwitz S, et al. J Neuroimmunol, 2010 Oct 8. PMID 20598377
    2. cDNA microarray analysis of altered gene expression in Ara-C-treated leukemia cells. Takagaki K, et al. Biochem Biophys Res Commun, 2003 Sep 19. PMID 12951057
    3. Transcriptome analysis of human gastric cancer. Oh JH, et al. Mamm Genome, 2005 Dec. PMID 16341674
    4. RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation. Wu SF, et al. Proc Natl Acad Sci U S A, 2020 Jun 23. PMID 32513696, Free PMC Article
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_134927.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript.
      Source sequence(s)
      BC042379
      Related
      ENST00000406892.6

    2. NR_134928.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks one exon and contains two alternate exons, compared to variant 1.
      Source sequence(s)
      BC042379, BM717321
      Related
      ENST00000476474.5

    3. NR_134929.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks two exons and contains two alternate exons, compared to variant 1.
      Source sequence(s)
      AA431306, BC042379, BP428722

    4. NR_134930.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks one exon and contains one alternate exon, compared to variant 1.
      Source sequence(s)
      BC042379, BG059081, BM854799
      Related
      ENST00000489336.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      11987617..12046275
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      12115811..12174482
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials