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    Zfp952 zinc finger protein 952 [ Mus musculus (house mouse) ]

    Gene ID: 240067, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Zfp952provided by MGI
    Official Full Name
    zinc finger protein 952provided by MGI
    Primary source
    MGI:MGI:2441928
    See related
    Ensembl:ENSMUSG00000053390 AllianceGenome:MGI:2441928
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C920016K16Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF124 (zinc finger protein 124). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 3.4), CNS E14 (RPKM 3.0) and 25 other tissues See more
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    Genomic context

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    See Zfp952 in Genome Data Viewer
    Location:
    17 B1; 17 17.98 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (33212083..33224431)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (32993108..33005457)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 41 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E7516 Neighboring gene zinc finger protein 472 Neighboring gene zinc finger protein 763 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:33170086-33170195 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:33170311-33170494 Neighboring gene PHD finger protein 8 like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC67168

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC240067

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045559.1 → NP_001039024.1  uncharacterized protein LOC240067

      Status: VALIDATED

      Source sequence(s)
      BC051011, CA320661, CT033772
      Consensus CDS
      CCDS37559.1
      UniProtKB/TrEMBL
      B0V2W4, D3Z6L1
      Related
      ENSMUSP00000084949.5, ENSMUST00000087666.11
      Conserved Domains (5) summary
      smart00349
      Location:10 → 50
      KRAB; krueppel associated box
      COG5048
      Location:234 → 494
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:337 → 357
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:10 → 49
      KRAB; KRAB box
      pfam13465
      Location:349 → 374
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      33212083..33224431
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249795.2 → XP_030105655.1  uncharacterized protein LOC240067 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:197 → 457
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:300 → 320
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_030249793.2 → XP_030105653.1  uncharacterized protein LOC240067 isoform X1

      Conserved Domains (3) summary
      COG5048
      Location:239 → 499
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:342 → 362
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:14 → 55
      KRAB; KRAB box

    3. XM_030249794.2 → XP_030105654.1  uncharacterized protein LOC240067 isoform X1

      Conserved Domains (3) summary
      COG5048
      Location:239 → 499
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:342 → 362
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:14 → 55
      KRAB; KRAB box

    4. XM_017317471.1 → XP_017172960.1  uncharacterized protein LOC240067 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:197 → 457
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:300 → 320
      ZF_C2H2; C2H2 Zn finger [structural motif]

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_199020.1: Suppressed sequence

      Description
      NM_199020.1: This RefSeq was permanently suppressed because it contains the wrong CDS.
    Nucleotide Protein Strain
    Heading Accession and Version

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