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    ZMIZ1-AS1 ZMIZ1 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 283050, updated on 10-Dec-2024

    Summary

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    Official Symbol
    ZMIZ1-AS1provided by HGNC
    Official Full Name
    ZMIZ1 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:27433
    See related
    Ensembl:ENSG00000224596 AllianceGenome:HGNC:27433
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Broad expression in testis (RPKM 1.8), skin (RPKM 1.0) and 21 other tissues See more
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    Genomic context

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    See ZMIZ1-AS1 in Genome Data Viewer
    Location:
    10q22.3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (78943326..79067448, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (79812581..79936725, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (80703083..80827205, complement)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107984246 Neighboring gene uncharacterized LOC105378378 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80231795-80232752 Neighboring gene VISTA enhancer hs1491 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80303319-80303820 Neighboring gene MPRA-validated peak1025 silencer Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:80319111-80320024 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80330027-80330528 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80330529-80331028 Neighboring gene uncharacterized LOC105378379 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80491819-80492320 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80492321-80492820 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80516074-80516712 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80517352-80517990 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80517991-80518628 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3618 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80527882-80528481 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80536737-80537624 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:80561226-80561763 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80587578-80588078 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80611199-80611786 Neighboring gene NANOG hESC enhancer GRCh37_chr10:80619958-80620464 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:80635056-80635704 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80660163-80660663 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80670266-80670770 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80670771-80671275 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr10:80673020-80673539 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80673540-80674060 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80675693-80676194 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80676195-80676694 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80696869-80697391 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80715276-80715991 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80724486-80725046 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:80726805-80727304 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80727311-80728094 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80731917-80732848 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3619 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2521 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2519 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2520 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80739778-80740278 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80740279-80740779 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3620 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:80742018-80742209 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80756413-80756912 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80768616-80769116 Neighboring gene uncharacterized LOC112268062 Neighboring gene CRISPRi-FlowFISH-validated PPIF regulatory element GRCh37_chr10:80782948-80783448 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr10:80806812-80808011 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3622 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80808619-80809301 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80814153-80814652 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2523 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2524 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2525 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80827637-80828482 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3623 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80832039-80832542 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80839841-80840350 Neighboring gene hESC enhancers GRCh37_chr10:80843535-80844106 and GRCh37_chr10:80844107-80844676 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2528 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80847474-80848460 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80848461-80849447 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80850069-80850570 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80850571-80851070 Neighboring gene CRISPRi-FlowFISH-validated PPIF regulatory elements GRCh37_chr10:80853442-80853942 and GRCh37_chr10:80853471-80853971 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80856811-80857382 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3625 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80860971-80861854 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80861855-80862738 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80862739-80863620 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:80867111-80867288 Neighboring gene HNF1 motif-containing MPRA enhancer 157 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80872521-80873111 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80873112-80873701 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80873702-80874292 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3626 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80874293-80874881 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2529 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80886414-80886932 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80889167-80889808 Neighboring gene CRISPRi-FlowFISH-validated PPIF regulatory element GRCh37_chr10:80892363-80892863 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80897004-80897684 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80904675-80905613 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3627 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2531 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2532 Neighboring gene zinc finger MIZ-type containing 1 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80915969-80916820 Neighboring gene HNF1 motif-containing MPRA enhancer 4 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80918523-80919372 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80922057-80922728 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80930785-80931574 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80937580-80938196 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80938197-80938813 Neighboring gene Sharpr-MPRA regulatory region 270 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80941281-80941897 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:80943423-80944622 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80944822-80945581 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80947279-80947814 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80947815-80948349 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80949957-80950491 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3628 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80960740-80961240 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80961241-80961741 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3629 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:80969381-80970255 Neighboring gene VISTA enhancer hs1767 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80984385-80985122 Neighboring gene Sharpr-MPRA regulatory region 8427 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80996160-80996788 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80996789-80997417 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80999304-80999932 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:80999933-81000560 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:81001601-81002552 Neighboring gene CRISPRi-FlowFISH-validated PPIF regulatory elements GRCh37_chr10:81003385-81003885 and GRCh37_chr10:81003389-81003889 Neighboring gene CRISPRi-FlowFISH-validated PPIF regulatory element GRCh37_chr10:81004281-81005113 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3632 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2537 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3635 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3633 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3634 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:81008726-81009639 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:81007811-81008725 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3637 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:81015755-81016750 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:81016751-81017746 Neighboring gene Sharpr-MPRA regulatory region 1120 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:81023533-81024492 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:81025451-81026410 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3638 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:81033176-81034046 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:81034047-81034918 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:81034919-81035789 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:81039443-81039612 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3639 Neighboring gene CRISPRi-FlowFISH-validated PPIF regulatory element GRCh37_chr10:81044989-81045489 Neighboring gene H3K4me1 hESC enhancers GRCh37_chr10:81046379-81047029 and GRCh37_chr10:81045728-81046378 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2538 Neighboring gene CRISPRi-FlowFISH-validated PPIF regulatory elements GRCh37_chr10:81053513-81054274 and GRCh37_chr10:81053559-81054389 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:81064163-81065362 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:81071537-81072037 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:81072795-81073294 Neighboring gene CRISPRi-FlowFISH-validated PPIF regulatory elements GRCh37_chr10:81076336-81076836 to GRCh37_chr10:81076368-81076868 Neighboring gene CRISPRi-FlowFISH-validated PPIF regulatory elements GRCh37_chr10:81077051-81077551 to GRCh37_chr10:81077572-81078072 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:81078090-81078665 Neighboring gene CRISPRi-FlowFISH-validated PPIF regulatory elements GRCh37_chr10:81080832-81081332 to GRCh37_chr10:81080873-81081373 Neighboring gene CRISPRi-FlowFISH-validated PPIF regulatory elements GRCh37_chr10:81082504-81083416 to GRCh37_chr10:81082920-81083420 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3643 Neighboring gene CRISPRi-FlowFISH-validated PPIF regulatory elements GRCh37_chr10:81088372-81088872 to GRCh37_chr10:81088582-81089082 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:81091043-81092242 Neighboring gene CRISPRi-FlowFISH-validated PPIF regulatory elements GRCh37_chr10:81106892-81107469 to GRCh37_chr10:81107706-81108206 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:81108973-81109473 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:81111476-81111976 Neighboring gene CRISPRi-FlowFISH-validated PPIF regulatory elements GRCh37_chr10:81112809-81113784 to GRCh37_chr10:81113845-81114345 Neighboring gene peptidylprolyl isomerase F

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Long non-coding RNA ZMIZ1-AS1 promotes osteosarcoma progression by stabilization of ZMIZ1. Zhou Y, et al. Cell Biol Toxicol, 2022 Dec. PMID 34508303
    2. Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. Zhang B, et al. Nat Genet, 2014 Jun. PMID 24836286, Free PMC Article
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Long non-coding RNA ZMIZ1-AS1 promotes osteosarcoma progression by stabilization of ZMIZ1.
      Title: Long non-coding RNA ZMIZ1-AS1 promotes osteosarcoma progression by stabilization of ZMIZ1.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Clone Names

    • FLJ44323, MGC125551

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_015429.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks two internal exons in the 5' region, as compared to variant 1.
      Source sequence(s)
      AK098249, BC102001, BX116874, CB306489

    2. NR_024429.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks two internal exons in the 5' and 3' regions respectively, as compared to variant 1.
      Source sequence(s)
      AK097923, AK098249, BC105703, CB306489
      Related
      ENST00000838132.1

    3. NR_024431.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) is the longest transcript.
      Source sequence(s)
      AK098249, AL356753, AL450398, CB306489
      Related
      ENST00000456353.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      78943326..79067448 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      79812581..79936725 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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