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    YIPF6 Yip1 domain family member 6 [ Homo sapiens (human) ]

    Gene ID: 286451, updated on 10-Dec-2024

    Summary

    Official Symbol
    YIPF6provided by HGNC
    Official Full Name
    Yip1 domain family member 6provided by HGNC
    Primary source
    HGNC:HGNC:28304
    See related
    Ensembl:ENSG00000181704 MIM:300996; AllianceGenome:HGNC:28304
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    Yip4; FinGER6; YIPFalpha3
    Summary
    Predicted to enable identical protein binding activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to act upstream of or within intestinal epithelial cell development. Located in Golgi apparatus subcompartment and endoplasmic reticulum. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in thyroid (RPKM 11.2), prostate (RPKM 8.9) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See YIPF6 in Genome Data Viewer
    Location:
    Xq12-q13.1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (68499051..68537282)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (66932508..66970741)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (67718893..67757124)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene oligophrenin 1 Neighboring gene akirin 1 pseudogene 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:67575188-67575688 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:67575689-67576189 Neighboring gene Sharpr-MPRA regulatory region 7273 Neighboring gene nuclear distribution protein nudE-like 1-like Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:67718059-67718733 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chrX:67767078-67767642 Neighboring gene RNA, U6 small nuclear 245, pseudogene Neighboring gene Sharpr-MPRA regulatory region 12156 Neighboring gene ribosomal protein L31 pseudogene 63

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Clone Names

    • MGC21416

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables identical protein binding  
    enables protein binding PubMed 
    Component Evidence Code Pubs
    located_in COPII-coated ER to Golgi transport vesicle  
    located_in Golgi medial cisterna PubMed 
    located_in Golgi membrane  
    located_in Golgi trans cisterna PubMed 
    located_in cis-Golgi network  
    located_in endoplasmic reticulum  
    is_active_in trans-Golgi network  
    located_in trans-Golgi network PubMed 

    General protein information

    Preferred Names
    protein YIPF6
    Names
    YIP1 family member 6

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195214.2 → NP_001182143.1  protein YIPF6 isoform B

      See identical proteins and their annotated locations for NP_001182143.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (B) lacks an in-frame exon in the 5' coding region, compared to variant A. The resulting protein (isoform B) is shorter than isoform A.
      Source sequence(s)
      AK303992, AL928603, CN311465
      Consensus CDS
      CCDS56604.1
      UniProtKB/TrEMBL
      B1AV70
      Related
      ENSP00000363751.2, ENST00000374622.3
      Conserved Domains (1) summary
      cl21557
      Location:22 → 188
      Yip1; Yip1 domain
    2. NM_173834.4 → NP_776195.2  protein YIPF6 isoform A

      See identical proteins and their annotated locations for NP_776195.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (A) represents the longer transcript and encodes the longer isoform (A).
      Source sequence(s)
      AL928603, BC012469
      Consensus CDS
      CCDS14389.1
      UniProtKB/Swiss-Prot
      B4E1U7, G5E997, Q5JP08, Q96EC8
      UniProtKB/TrEMBL
      A8K9X0
      Related
      ENSP00000417573.1, ENST00000462683.6
      Conserved Domains (1) summary
      cl21557
      Location:54 → 231
      Yip1; Yip1 domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      68499051..68537282
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      66932508..66970741
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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