NCAM2 neural cell adhesion molecule 2 [Homo sapiens (human)] - Gene

Summary

Official Symbol: NCAM2provided by HGNC
Official Full Name: neural cell adhesion molecule 2provided by HGNC
Primary source: HGNC:HGNC:7657
See related: Ensembl:ENSG00000154654 MIM:602040; AllianceGenome:HGNC:7657
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: NCAM21
Summary: The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein and may function in selective fasciculation and zone-to-zone projection of the primary olfactory axons. [provided by RefSeq, Jul 2008]
Expression: Biased expression in brain (RPKM 13.1), adrenal (RPKM 3.2) and 3 other tissues See more
Orthologs: mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 21q21.1

Exon count:: 26

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	21	NC_000021.9 (20998409..21543329)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	21	NC_060945.1 (19360795..19909385)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	21	NC_000021.8 (22370727..22915650)

Chromosome 21 - NC_000021.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Tissue-specific circular RNA induction during human fetal development
Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
BioProject: PRJNA270632
Publication: PMID 26076956
Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

NCAM2 Regulates Dendritic and Axonal Differentiation through the Cytoskeletal Proteins MAP2 and 14-3-3.
Title: NCAM2 Regulates Dendritic and Axonal Differentiation through the Cytoskeletal Proteins MAP2 and 14-3-3.
Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo.
Title: Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo.
These results reveal that the NCAM2 FnIII domains form a rigid structure that binds and activates FGFR in a manner related to, but different from NCAM1.
Title: NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor.
Our reported case raises the questions whether the NCAM2-deletion is the true cause of the autism spectrum disorder or only a risk factor and whether there might be any connection in NCAM2 with skull-size
Title: NCAM2 deletion in a boy with macrocephaly and autism: Cause, association or predisposition?
Abeta-dependent disruption of NCAM2 functions in Alzheimer's disease hippocampus contributes to synapse loss.
Title: Aβ-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer's disease.
A complete structural model of the entire ectodomain of human NCAM2 has been assembled from crystal structures of six recombinant proteins corresponding to different regions of the ectodomain.
Title: Structural model and trans-interaction of the entire ectodomain of the olfactory cell adhesion molecule.
High NCAM2 is associated with increased 5-Fluorouracil sensitivity in prostate and breast cancer.
Title: Neural cell adhesion molecule 2 as a target molecule for prostate and breast cancer gene therapy.
Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
Title: Genome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study.
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Observational study of gene-disease association. (HuGE Navigator)
Title: Association of polymorphisms in the SLIT2 axonal guidance gene with anger in suicide attempters.

Submit: New GeneRIF Correction See all GeneRIFs (11)

Phenotypes

Go to the top of the page Help

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
A genome-wide association study on obesity and obesity-related traits. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families. EBI GWAS Catalog EBI GWAS CatalogPubMed
Joint influence of small-effect genetic variants on human longevity. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

D21S178 (e-PCR)
- UniSTS:148746

STS_CEB261 (e-PCR)
- UniSTS:255259

SHGC-87507 (e-PCR)
- UniSTS:80415

SHGC-7315 (e-PCR)
- UniSTS:85800

D21S414 (e-PCR)
- UniSTS:148063

G63280 (e-PCR)
- UniSTS:140393

RH92742 (e-PCR)
- UniSTS:91562

NCAM2 (e-PCR)
- UniSTS:266420

RH119251 (e-PCR)
- UniSTS:133814

SHGC-51842 (e-PCR)
- UniSTS:10935

D21S1884 (e-PCR), detects polymorphism
- UniSTS:70850

RH122996 (e-PCR)
- UniSTS:135388

SHGC-6935 (e-PCR)
- UniSTS:91873

D21S214 (e-PCR), detects polymorphism
- UniSTS:58864

SHGC-51821 (e-PCR)
- UniSTS:60914

SHGC-145550 (e-PCR)
- UniSTS:172543

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in axonal fasciculation	IEA Inferred from Electronic Annotation more info
involved_in neuron cell-cell adhesion	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in axon	IEA Inferred from Electronic Annotation more info
located_in membrane	TAS Traceable Author Statement more info	PubMed
is_active_in neuron projection	IBA Inferred from Biological aspect of Ancestor more info
located_in nuclear body	IDA Inferred from Direct Assay more info
located_in plasma membrane	IDA Inferred from Direct Assay more info
located_in synaptic membrane	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: neural cell adhesion molecule 2

Names: N-CAM-2; NCAM-2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001352591.2 → NP_001339520.1 neural cell adhesion molecule 2 isoform 1 precursor

Status: REVIEWED

Source sequence(s)

AP001115, AP001137, AP001138, AP001252

UniProtKB/TrEMBL

H9KV31

Conserved Domains (6) summary

cd05866
Location:21 → 112

Ig1_NCAM-2; First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-2

cd05870
Location:300 → 397

Ig_NCAM-2; Immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-2 (also known as OCAM/mamFas II and RNCAM)

cd00063
Location:496 → 588

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:594 → 678

fn3; Fibronectin type III domain

pfam13927
Location:401 → 479

Ig_3; Immunoglobulin domain

cl11960
Location:208 → 301

Ig; Immunoglobulin domain
NM_001352592.2 → NP_001339521.1 neural cell adhesion molecule 2 isoform 3

Status: REVIEWED

Source sequence(s)

AP001115, AP001136, AP001137, AP001138, AP001252

UniProtKB/TrEMBL

H9KV31

Conserved Domains (6) summary

cd05866
Location:46 → 137

Ig1_NCAM-2; First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-2

cd05870
Location:325 → 422

Ig_NCAM-2; Immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-2 (also known as OCAM/mamFas II and RNCAM)

cd00063
Location:521 → 613

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:619 → 703

fn3; Fibronectin type III domain

pfam13927
Location:426 → 504

Ig_3; Immunoglobulin domain

cl11960
Location:233 → 326

Ig; Immunoglobulin domain
NM_001352593.2 → NP_001339522.1 neural cell adhesion molecule 2 isoform 4 precursor

Status: REVIEWED

Source sequence(s)

AP001137, AP001138, AP001252

UniProtKB/TrEMBL

H9KV31

Conserved Domains (6) summary

cd05866
Location:21 → 112

Ig1_NCAM-2; First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-2

cd05870
Location:300 → 397

Ig_NCAM-2; Immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-2 (also known as OCAM/mamFas II and RNCAM)

cd00063
Location:496 → 588

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:594 → 678

fn3; Fibronectin type III domain

pfam13927
Location:401 → 479

Ig_3; Immunoglobulin domain

cl11960
Location:208 → 301

Ig; Immunoglobulin domain
NM_001352594.2 → NP_001339523.1 neural cell adhesion molecule 2 isoform 5 precursor

Status: REVIEWED

Source sequence(s)

AP001137, AP001138, AP001252

UniProtKB/TrEMBL

H9KV31

Conserved Domains (6) summary

cd05866
Location:21 → 112

Ig1_NCAM-2; First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-2

cd05870
Location:300 → 397

Ig_NCAM-2; Immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-2 (also known as OCAM/mamFas II and RNCAM)

cd00063
Location:496 → 588

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:594 → 678

fn3; Fibronectin type III domain

pfam13927
Location:401 → 479

Ig_3; Immunoglobulin domain

cl11960
Location:208 → 301

Ig; Immunoglobulin domain
NM_001352595.2 → NP_001339524.1 neural cell adhesion molecule 2 isoform 6 precursor

Status: REVIEWED

Source sequence(s)

AK299054, AP001115, AP001137

UniProtKB/TrEMBL

B7Z5K2

Conserved Domains (5) summary

cd05870
Location:158 → 255

Ig_NCAM-2; Immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-2 (also known as OCAM/mamFas II and RNCAM)

cd00063
Location:354 → 446

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:452 → 536

fn3; Fibronectin type III domain

pfam13927
Location:259 → 337

Ig_3; Immunoglobulin domain

cl11960
Location:66 → 159

Ig; Immunoglobulin domain
NM_001352596.2 → NP_001339525.1 neural cell adhesion molecule 2 isoform 7 precursor

Status: REVIEWED

Source sequence(s)

AI500562, AP001137, AP001138, AP001252

Conserved Domains (5) summary

cd05866
Location:21 → 112

Ig1_NCAM-2; First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-2

cd05870
Location:300 → 397

Ig_NCAM-2; Immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-2 (also known as OCAM/mamFas II and RNCAM)

cd00063
Location:496 → 556

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam13927
Location:401 → 479

Ig_3; Immunoglobulin domain

cl11960
Location:208 → 301

Ig; Immunoglobulin domain
NM_001352597.2 → NP_001339526.1 neural cell adhesion molecule 2 isoform 8

Status: REVIEWED

Source sequence(s)

AK302870

Conserved Domains (4) summary

cd05866
Location:46 → 137

Ig1_NCAM-2; First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-2

cd05870
Location:325 → 422

Ig_NCAM-2; Immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-2 (also known as OCAM/mamFas II and RNCAM)

pfam13927
Location:147 → 212

Ig_3; Immunoglobulin domain

cl11960
Location:233 → 326

Ig; Immunoglobulin domain
NM_004540.5 → NP_004531.2 neural cell adhesion molecule 2 isoform 2 precursor

See identical proteins and their annotated locations for NP_004531.2

Status: REVIEWED

Source sequence(s)

AI207079, AP001115, BC052946

Consensus CDS

CCDS42910.1

UniProtKB/Swiss-Prot

A8MQ06, B7Z841, O15394, Q7Z7F2

UniProtKB/TrEMBL

H9KV31

Related

ENSP00000383392.1, ENST00000400546.6

Conserved Domains (8) summary

cd05866
Location:21 → 112

Ig1_NCAM-2; First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-2

cd05870
Location:300 → 397

Ig5_NCAM-2; Fifth immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-2 (also known as OCAM/mamFas II and RNCAM)

smart00408
Location:414 → 482

IGc2; Immunoglobulin C-2 Type

smart00410
Location:308 → 395

IG_like; Immunoglobulin like

cd00063
Location:496 → 588

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam07679
Location:22 → 111

I-set; Immunoglobulin I-set domain

pfam00041
Location:594 → 678

fn3; Fibronectin type III domain

cl11960
Location:208 → 301

Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000021.9 Reference GRCh38.p14 Primary Assembly

Range

20998409..21543329

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_047440785.1 → XP_047296741.1 neural cell adhesion molecule 2 isoform X6

UniProtKB/TrEMBL

H9KV31
XM_024452081.2 → XP_024307849.1 neural cell adhesion molecule 2 isoform X7

UniProtKB/TrEMBL

H9KV31

Conserved Domains (6) summary

cd05866
Location:21 → 112

Ig1_NCAM-2; First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-2

cd05870
Location:300 → 397

Ig_NCAM-2; Immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-2 (also known as OCAM/mamFas II and RNCAM)

cd00063
Location:496 → 588

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:594 → 678

fn3; Fibronectin type III domain

pfam13927
Location:401 → 479

Ig_3; Immunoglobulin domain

cl11960
Location:208 → 301

Ig; Immunoglobulin domain
XM_011529575.4 → XP_011527877.1 neural cell adhesion molecule 2 isoform X1

See identical proteins and their annotated locations for XP_011527877.1

UniProtKB/TrEMBL

H9KV31

Conserved Domains (8) summary

cd05870
Location:325 → 422

IgI_NCAM-2; Immunoglobulin (Ig)-like I-set domain of Neural Cell Adhesion Molecule 2 (NCAM-2)

smart00408
Location:153 → 214

IGc2; Immunoglobulin C-2 Type

cd00063
Location:521 → 613

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:619 → 703

fn3; Fibronectin type III domain

pfam13927
Location:426 → 504

Ig_3; Immunoglobulin domain

cd00096
Location:443 → 447

Ig; Ig strand B [structural motif]

cd05866
Location:46 → 138

IgI_1_NCAM-2; First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-2; member of the I-set of Ig superfamily (IgSF) domains

cd20970
Location:234 → 323

IgI_1_MuSK; agrin-responsive first immunoglobulin-like domains (Ig1) of the MuSK ectodomain; a member of the I-set of IgSF domains
XM_047440784.1 → XP_047296740.1 neural cell adhesion molecule 2 isoform X2

UniProtKB/TrEMBL

H9KV31
XM_011529581.4 → XP_011527883.1 neural cell adhesion molecule 2 isoform X4

UniProtKB/TrEMBL

H9KV31

Conserved Domains (8) summary

cd05866
Location:46 → 137

Ig1_NCAM-2; First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-2

cd05870
Location:325 → 422

Ig5_NCAM-2; Fifth immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-2 (also known as OCAM/mamFas II and RNCAM)

smart00408
Location:439 → 507

IGc2; Immunoglobulin C-2 Type

smart00410
Location:333 → 420

IG_like; Immunoglobulin like

cd00063
Location:521 → 613

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam07679
Location:47 → 136

I-set; Immunoglobulin I-set domain

pfam00041
Location:619 → 703

fn3; Fibronectin type III domain

cl11960
Location:233 → 326

Ig; Immunoglobulin domain
XM_011529580.4 → XP_011527882.1 neural cell adhesion molecule 2 isoform X3

UniProtKB/TrEMBL

H9KV31

Conserved Domains (8) summary

cd05866
Location:46 → 137

Ig1_NCAM-2; First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-2

cd05870
Location:325 → 422

Ig5_NCAM-2; Fifth immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-2 (also known as OCAM/mamFas II and RNCAM)

smart00408
Location:439 → 507

IGc2; Immunoglobulin C-2 Type

smart00410
Location:333 → 420

IG_like; Immunoglobulin like

cd00063
Location:521 → 613

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam07679
Location:47 → 136

I-set; Immunoglobulin I-set domain

pfam00041
Location:619 → 703

fn3; Fibronectin type III domain

cl11960
Location:233 → 326

Ig; Immunoglobulin domain
XM_011529582.4 → XP_011527884.1 neural cell adhesion molecule 2 isoform X5

UniProtKB/TrEMBL

H9KV31

Conserved Domains (8) summary

cd05866
Location:46 → 137

Ig1_NCAM-2; First immunoglobulin (Ig)-like domain of neural cell adhesion molecule NCAM-2

cd05870
Location:325 → 422

Ig5_NCAM-2; Fifth immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-2 (also known as OCAM/mamFas II and RNCAM)

smart00408
Location:439 → 507

IGc2; Immunoglobulin C-2 Type

smart00410
Location:333 → 420

IG_like; Immunoglobulin like

cd00063
Location:521 → 613

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam07679
Location:47 → 136

I-set; Immunoglobulin I-set domain

pfam00041
Location:619 → 703

fn3; Fibronectin type III domain

cl11960
Location:233 → 326

Ig; Immunoglobulin domain
XM_017028356.3 → XP_016883845.1 neural cell adhesion molecule 2 isoform X8

UniProtKB/TrEMBL

B7Z5K2

Conserved Domains (7) summary

cd05870
Location:136 → 233

Ig5_NCAM-2; Fifth immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-2 (also known as OCAM/mamFas II and RNCAM)

smart00408
Location:250 → 318

IGc2; Immunoglobulin C-2 Type

smart00410
Location:144 → 231

IG_like; Immunoglobulin like

cd00063
Location:332 → 424

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam07679
Location:51 → 134

I-set; Immunoglobulin I-set domain

pfam00041
Location:430 → 514

fn3; Fibronectin type III domain

cl11960
Location:44 → 137

Ig; Immunoglobulin domain
XM_011529585.3 → XP_011527887.1 neural cell adhesion molecule 2 isoform X8

See identical proteins and their annotated locations for XP_011527887.1

UniProtKB/TrEMBL

B7Z5K2

Conserved Domains (7) summary

cd05870
Location:136 → 233

Ig5_NCAM-2; Fifth immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-2 (also known as OCAM/mamFas II and RNCAM)

smart00408
Location:250 → 318

IGc2; Immunoglobulin C-2 Type

smart00410
Location:144 → 231

IG_like; Immunoglobulin like

cd00063
Location:332 → 424

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam07679
Location:51 → 134

I-set; Immunoglobulin I-set domain

pfam00041
Location:430 → 514

fn3; Fibronectin type III domain

cl11960
Location:44 → 137

Ig; Immunoglobulin domain

Alternate T2T-CHM13v2.0

Genomic

NC_060945.1 Alternate T2T-CHM13v2.0

Range

19360795..19909385

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054324515.1 → XP_054180490.1 neural cell adhesion molecule 2 isoform X1

UniProtKB/TrEMBL

H9KV31
XM_054324520.1 → XP_054180495.1 neural cell adhesion molecule 2 isoform X6

UniProtKB/TrEMBL

H9KV31
XM_054324521.1 → XP_054180496.1 neural cell adhesion molecule 2 isoform X7

UniProtKB/TrEMBL

H9KV31
XM_054324514.1 → XP_054180489.1 neural cell adhesion molecule 2 isoform X1

UniProtKB/TrEMBL

H9KV31
XM_054324516.1 → XP_054180491.1 neural cell adhesion molecule 2 isoform X2

UniProtKB/TrEMBL

H9KV31
XM_054324518.1 → XP_054180493.1 neural cell adhesion molecule 2 isoform X4

UniProtKB/TrEMBL

H9KV31
XM_054324517.1 → XP_054180492.1 neural cell adhesion molecule 2 isoform X3

UniProtKB/TrEMBL

H9KV31
XM_054324519.1 → XP_054180494.1 neural cell adhesion molecule 2 isoform X5

UniProtKB/TrEMBL

H9KV31
XM_054324523.1 → XP_054180498.1 neural cell adhesion molecule 2 isoform X8

UniProtKB/TrEMBL

B7Z5K2
XM_054324522.1 → XP_054180497.1 neural cell adhesion molecule 2 isoform X8

UniProtKB/TrEMBL

B7Z5K2