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    Rnf215 ring finger protein 215 [ Mus musculus (house mouse) ]

    Gene ID: 71673, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rnf215provided by MGI
    Official Full Name
    ring finger protein 215provided by MGI
    Primary source
    MGI:MGI:1918923
    See related
    Ensembl:ENSMUSG00000003581 AllianceGenome:MGI:1918923
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    0610009J22Rik
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in membrane. Predicted to be active in cytoplasm. Orthologous to human RNF215 (ring finger protein 215). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in lung adult (RPKM 27.0), ovary adult (RPKM 20.1) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rnf215 in Genome Data Viewer
    Location:
    11 A1; 11 2.89 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (4085158..4091193)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (4135157..4141193)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene SEC14-like lipid binding 2 Neighboring gene predicted gene, 51934 Neighboring gene transformer 2 beta homolog pseudogene Neighboring gene microRNA 3060 Neighboring gene coiled-coil domain containing 157 Neighboring gene splicing factor 3a, subunit 1 Neighboring gene STARR-positive B cell enhancer ABC_E727 Neighboring gene TBC1 domain family, member 10a Neighboring gene STARR-positive B cell enhancer ABC_E2978 Neighboring gene cytosolic arginine sensor for mTORC1 subunit 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Clone Names

    • MGC106323, MGC144708, MGC144709

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001363143.1NP_001350072.1  RING finger protein 215 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AL807825
      Conserved Domains (1) summary
      cd16670
      Location:298347
      RING-H2_RNF215; RING finger, H2 subclass, found in RING finger protein 215 (RNF215) and similar proteins
    2. NM_027859.3NP_082135.2  RING finger protein 215 isoform 1 precursor

      See identical proteins and their annotated locations for NP_082135.2

      Status: VALIDATED

      Source sequence(s)
      BC115907, BM120893, BM948157, CX203997
      Consensus CDS
      CCDS24378.1
      UniProtKB/Swiss-Prot
      Q5SPX2, Q5SPX3, Q5SPX4, Q9DCW1
      Related
      ENSMUSP00000003677.5, ENSMUST00000003677.11
      Conserved Domains (1) summary
      pfam13639
      Location:325368
      zf-RING_2; Ring finger domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      4085158..4091193
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_003949509.2 RNA Sequence

    2. XR_380981.4 RNA Sequence