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    Ccdc68 coiled-coil domain containing 68 [ Mus musculus (house mouse) ]

    Gene ID: 381175, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ccdc68provided by MGI
    Official Full Name
    coiled-coil domain containing 68provided by MGI
    Primary source
    MGI:MGI:3612676
    See related
    Ensembl:ENSMUSG00000038903 AllianceGenome:MGI:3612676
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be involved in microtubule anchoring at centrosome. Predicted to be located in cytoplasm. Predicted to be part of centriolar subdistal appendage. Predicted to be active in centriole. Orthologous to human CCDC68 (coiled-coil domain containing 68). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in placenta adult (RPKM 9.7), bladder adult (RPKM 2.2) and 8 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ccdc68 in Genome Data Viewer
    Location:
    18 E2; 18 43.78 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (70057929..70102559)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (69924858..69969488)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31564 Neighboring gene STARR-seq mESC enhancer starr_44954 Neighboring gene predicted gene, 36175 Neighboring gene STARR-seq mESC enhancer starr_44955 Neighboring gene crumbs homolog 1 pseudogene Neighboring gene RAB27B, member RAS oncogene family Neighboring gene STARR-seq mESC enhancer starr_44957 Neighboring gene predicted gene, 41770 Neighboring gene STARR-seq mESC enhancer starr_44958 Neighboring gene dynactin associated protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Clone Names

    • MGC54896

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in microtubule anchoring at centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in microtubule anchoring at centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein localization IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of centriolar subdistal appendage IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in centriole IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    coiled-coil domain-containing protein 68

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201362.2NP_958750.1  coiled-coil domain-containing protein 68

      See identical proteins and their annotated locations for NP_958750.1

      Status: PROVISIONAL

      Source sequence(s)
      AK078964
      Consensus CDS
      CCDS29330.1
      UniProtKB/Swiss-Prot
      Q80VD6, Q8BVC4
      Related
      ENSMUSP00000046197.5, ENSMUST00000043929.11
      Conserved Domains (1) summary
      COG1196
      Location:68294
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      70057929..70102559
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006526070.3XP_006526133.1  coiled-coil domain-containing protein 68 isoform X1

      Conserved Domains (1) summary
      COG1196
      Location:144396
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    2. XM_006526071.3XP_006526134.1  coiled-coil domain-containing protein 68 isoform X2

      Conserved Domains (1) summary
      COG1196
      Location:144370
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    3. XM_006526076.3XP_006526139.1  coiled-coil domain-containing protein 68 isoform X4

      See identical proteins and their annotated locations for XP_006526139.1

      Conserved Domains (1) summary
      COG1196
      Location:68320
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    4. XM_017317935.1XP_017173424.1  coiled-coil domain-containing protein 68 isoform X3

      Conserved Domains (1) summary
      COG1196
      Location:73325
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    5. XM_006526075.3XP_006526138.1  coiled-coil domain-containing protein 68 isoform X4

      See identical proteins and their annotated locations for XP_006526138.1

      Conserved Domains (1) summary
      COG1196
      Location:68320
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    6. XM_006526074.3XP_006526137.1  coiled-coil domain-containing protein 68 isoform X4

      See identical proteins and their annotated locations for XP_006526137.1

      Conserved Domains (1) summary
      COG1196
      Location:68320
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    7. XM_011246971.3XP_011245273.1  coiled-coil domain-containing protein 68 isoform X4

      See identical proteins and their annotated locations for XP_011245273.1

      Conserved Domains (1) summary
      COG1196
      Location:68320
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]