Cox8a cytochrome c oxidase subunit 8A [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Cox8aprovided by MGI
Official Full Name: cytochrome c oxidase subunit 8Aprovided by MGI
Primary source: MGI:MGI:105959
See related: Ensembl:ENSMUSG00000035885 AllianceGenome:MGI:105959
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: COX8L
Summary: Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrion. Is expressed in several structures, including alimentary system; liver; nervous system; nose; and urinary system. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 15. Orthologous to human COX8A (cytochrome c oxidase subunit 8A). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in duodenum adult (RPKM 1660.4), colon adult (RPKM 1505.4) and 27 other tissues See more
Orthologs: human all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 19 A; 19 5.28 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	19	NC_000085.7 (7192523..7194981, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	19	NC_000085.6 (7215158..7217616, complement)

Chromosome 19 - NC_000085.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

Go to the top of the page Help

Markers

NoName (e-PCR)
- UniSTS:494121

Cox8a (e-PCR), detects polymorphism
- UniSTS:546706

NoName (e-PCR)
- UniSTS:492998

Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
involved_in mitochondrial electron transport, cytochrome c to oxygen	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	HDA more info	PubMed
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex IV	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex IV	IEA Inferred from Electronic Annotation more info
part_of respiratory chain complex IV	ISO Inferred from Sequence Orthology more info

General protein information

Go to the top of the page Help

Preferred Names: cytochrome c oxidase subunit 8A, mitochondrial

Names: COX VIII-L; cytochrome c oxidase polypeptide VIII-liver; cytochrome c oxidase subunit 8-2; cytochrome c oxidase subunit VIIIa

NP_031776.1

EC 7.1.1.9

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.