Xrra1 X-ray radiation resistance associated 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Xrra1provided by MGI
Official Full Name: X-ray radiation resistance associated 1provided by MGI
Primary source: MGI:MGI:2181647
See related: Ensembl:ENSMUSG00000035211 AllianceGenome:MGI:2181647
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to be involved in response to X-ray. Predicted to be located in cytoplasm and nuclear body. Predicted to be active in nucleus. Orthologous to human XRRA1 (X-ray radiation resistance associated 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in testis adult (RPKM 88.3), adrenal adult (RPKM 15.3) and 1 other tissue See more
Orthologs: human all
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Genomic context

Location:: 7 E1- E2; 7 54.15 cM

Exon count:: 21

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (99508425..99567031)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (99859218..99917824)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in response to X-ray	ISO Inferred from Sequence Orthology more info
involved_in response to X-ray	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in nuclear body	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: X-ray radiation resistance-associated protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001164258.1 → NP_001157730.1 X-ray radiation resistance-associated protein 1

See identical proteins and their annotated locations for NP_001157730.1

Status: VALIDATED

Source sequence(s)

BC151014, BK000542

Consensus CDS

CCDS52321.1

UniProtKB/Swiss-Prot

B2RX67, Q3U3V8, Q7M740

UniProtKB/TrEMBL

A0A991ENW4

Related

ENSMUSP00000035929.9, ENSMUST00000036155.10

Conserved Domains (3) summary

PRK15370
Location:237 → 421

PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP

COG4886
Location:136 → 276

LRR; Leucine-rich repeat (LRR) protein [Transcription]

sd00031
Location:147 → 169

LRR_1; leucine-rich repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000073.7 Reference GRCm39 C57BL/6J

Range

99508425..99567031

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017322345.2 → XP_017177834.1 X-ray radiation resistance-associated protein 1 isoform X1

UniProtKB/TrEMBL

A0A991ENW4

Conserved Domains (3) summary

PRK15370
Location:239 → 423

PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP

COG4886
Location:138 → 278

LRR; Leucine-rich repeat (LRR) protein [Transcription]

sd00031
Location:149 → 171

LRR_1; leucine-rich repeat [structural motif]
XM_006508007.4 → XP_006508070.1 X-ray radiation resistance-associated protein 1 isoform X2

See identical proteins and their annotated locations for XP_006508070.1

UniProtKB/Swiss-Prot

B2RX67, Q3U3V8, Q7M740

UniProtKB/TrEMBL

A0A991ENW4

Conserved Domains (3) summary

PRK15370
Location:237 → 421

PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP

COG4886
Location:136 → 276

LRR; Leucine-rich repeat (LRR) protein [Transcription]

sd00031
Location:147 → 169

LRR_1; leucine-rich repeat [structural motif]
XM_017322346.1 → XP_017177835.1 X-ray radiation resistance-associated protein 1 isoform X3

Related

ENSMUST00000208449.2