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    Tceanc transcription elongation factor A (SII) N-terminal and central domain containing [ Mus musculus (house mouse) ]

    Gene ID: 245695, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Tceancprovided by MGI
    Official Full Name
    transcription elongation factor A (SII) N-terminal and central domain containingprovided by MGI
    Primary source
    MGI:MGI:2685236
    See related
    Ensembl:ENSMUSG00000051224 AllianceGenome:MGI:2685236
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm390; A630018P17Rik
    Summary
    Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human TCEANC (transcription elongation factor A N-terminal and central domain containing). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 1.6), CNS E11.5 (RPKM 1.3) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tceanc in Genome Data Viewer
    Location:
    X F5; X 77.59 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (165282806..165301594, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (166499810..166518603, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 154, member A pseudogene Neighboring gene predicted gene 15223 Neighboring gene STARR-seq mESC enhancer starr_48253 Neighboring gene EGF-like-domain, multiple 6 Neighboring gene STARR-seq mESC enhancer starr_48256 Neighboring gene STARR-seq mESC enhancer starr_48259 Neighboring gene CapStarr-seq enhancer MGSCv37_chrX:163099414-163099597 Neighboring gene predicted gene 1720

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. Shalom-Barak T, et al. Dev Biol, 2012 Dec 1. PMID 22967998, Free PMC Article
    2. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Clone Names

    • MGC93029

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    transcription elongation factor A N-terminal and central domain-containing protein
    Names
    TFIIS central domain-containing protein 1
    TFS2-M domain-containing protein 1
    novel transcription factor S-II (TFIIS), central domain containing protein

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007577.2 → NP_001007578.2  transcription elongation factor A N-terminal and central domain-containing protein

      See identical proteins and their annotated locations for NP_001007578.2

      Status: VALIDATED

      Source sequence(s)
      AK140929, AL672174, BU611745, CO044580
      Consensus CDS
      CCDS53249.1
      UniProtKB/Swiss-Prot
      Q3US16, Q6NXL9, Q8BY92
      Related
      ENSMUSP00000107806.2, ENSMUST00000112188.8
      Conserved Domains (2) summary
      pfam07500
      Location:181 → 290
      TFIIS_M; Transcription factor S-II (TFIIS), central domain
      cl02609
      Location:298 → 351
      Zn-ribbon; C-terminal zinc ribbon domain of RNA polymerase intrinsic transcript cleavage subunit

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      165282806..165301594 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011247827.4 → XP_011246129.1  transcription elongation factor A N-terminal and central domain-containing protein isoform X1

      See identical proteins and their annotated locations for XP_011246129.1

      UniProtKB/Swiss-Prot
      Q3US16, Q6NXL9, Q8BY92
      Related
      ENSMUSP00000136691.2, ENSMUST00000180322.2
      Conserved Domains (2) summary
      pfam07500
      Location:181 → 290
      TFIIS_M; Transcription factor S-II (TFIIS), central domain
      cl02609
      Location:298 → 351
      Zn-ribbon; C-terminal zinc ribbon domain of RNA polymerase intrinsic transcript cleavage subunit

    2. XM_006528863.5 → XP_006528926.1  transcription elongation factor A N-terminal and central domain-containing protein isoform X1

      See identical proteins and their annotated locations for XP_006528926.1

      UniProtKB/Swiss-Prot
      Q3US16, Q6NXL9, Q8BY92
      Conserved Domains (2) summary
      pfam07500
      Location:181 → 290
      TFIIS_M; Transcription factor S-II (TFIIS), central domain
      cl02609
      Location:298 → 351
      Zn-ribbon; C-terminal zinc ribbon domain of RNA polymerase intrinsic transcript cleavage subunit
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3US16.1 GenPept UniProtKB/Swiss-Prot:Q3US16

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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