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    CDKL3 cyclin dependent kinase like 3 [ Homo sapiens (human) ]

    Gene ID: 51265, updated on 10-Dec-2024

    Summary

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    Official Symbol
    CDKL3provided by HGNC
    Official Full Name
    cyclin dependent kinase like 3provided by HGNC
    Primary source
    HGNC:HGNC:15483
    See related
    Ensembl:ENSG00000006837 MIM:608459; AllianceGenome:HGNC:15483
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    NKIAMRE
    Summary
    The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
    Expression
    Biased expression in testis (RPKM 4.9), brain (RPKM 1.0) and 12 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See CDKL3 in Genome Data Viewer
    Location:
    5q31.1
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (134283345..134371624, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (134806646..134895410, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (133634115..133706734, complement)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:133562023-133562544 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:133562545-133563064 Neighboring gene PPP2CA divergent transcript Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23141 Neighboring gene ribosomal protein S13 pseudogene 6 Neighboring gene MPRA-validated peak5475 silencer Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:133680746-133681444 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:133681445-133682144 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:133706379-133706974 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16357 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23143 Neighboring gene ubiquitin conjugating enzyme E2 B Neighboring gene CDKN2A interacting protein N-terminal like Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:133746964-133747702 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:133747703-133748440 Neighboring gene ribosomal protein S10 pseudogene 11

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. CDKL3 Promotes Non-small Cell Lung Cancer by Suppressing Autophagy Via Activation of PI3K/Akt/mTOR Pathway. Li R, et al. Mol Biotechnol, 2023 Sep. PMID 36630073
    2. Identification of NKIAMRE, the human homologue to the mitogen-activated protein kinase-/cyclin-dependent kinase-related protein kinase NKIATRE, and its loss in leukemic blasts with chromosome arm 5q deletion. Midmer M, et al. Cancer Res, 1999 Aug 15. PMID 10463609
    3. NKIAMRE, a novel conserved CDC2-related kinase with features of both mitogen-activated protein kinases and cyclin-dependent kinases. Yee KW, et al. Biochem Biophys Res Commun, 2003 Sep 5. PMID 12927787
    4. CDKL3 promotes osteosarcoma progression by activating Akt/PKB. He A, et al. Life Sci Alliance, 2020 May. PMID 32234750, Free PMC Article
    5. Cyclin-dependent kinase like 3 promotes triple-negative breast cancer progression via inhibiting the p53 signaling pathway. Zeng DX, et al. Neoplasma, 2021 Sep. PMID 34427098

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CDKL3 Promotes Non-small Cell Lung Cancer by Suppressing Autophagy Via Activation of PI3K/Akt/mTOR Pathway.
      Title: CDKL3 Promotes Non-small Cell Lung Cancer by Suppressing Autophagy Via Activation of PI3K/Akt/mTOR Pathway.
    2. CircTP53 promotes colorectal cancer by acting as a miR-876-3p sponge to increase cyclin-dependent kinase-like 3 expression.
      Title: CircTP53 promotes colorectal cancer by acting as a miR-876-3p sponge to increase cyclin-dependent kinase-like 3 expression.
    3. Cyclin-dependent kinase like 3 promotes triple-negative breast cancer progression via inhibiting the p53 signaling pathway.
      Title: Cyclin-dependent kinase like 3 promotes triple-negative breast cancer progression via inhibiting the p53 signaling pathway.
    4. Identification of CDKL3 as a critical regulator in development of glioma through regulating RRM2 and the JNK signaling pathway.
      Title: Identification of CDKL3 as a critical regulator in development of glioma through regulating RRM2 and the JNK signaling pathway.
    5. CDKL3 promotes osteosarcoma progression by activating Akt/PKB.
      Title: CDKL3 promotes osteosarcoma progression by activating Akt/PKB.
    6. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
      Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    7. data suggest that the CDKL3 gene is a strong candidate for nonsyndromal autosomal dominant mild mental retardation
      Title: Inactivation of the CDKL3 gene at 5q31.1 by a balanced t(X;5) translocation associated with nonspecific mild mental retardation.
    8. cdkl3 transfected in anchorage-independent (suspension) HeLa cells overexpressed relative to attached cells and lead to elevated proliferation and faster transition G0/G1 phases to S phase relative to controls. Same in two HEK-293 and a CHO cell lines.
      Title: Enhancement of cell proliferation in various mammalian cell lines by gene insertion of a cyclin-dependent kinase homolog.
    9. NKIAMRE is a member of a conserved family of kinases with homology to both MAP kinases and cyclin-dependent kinases
      Title: NKIAMRE, a novel conserved CDC2-related kinase with features of both mitogen-activated protein kinases and cyclin-dependent kinases.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cyclin-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in dendrite extension IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of axon extension IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of dendrite morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein modification process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cyclin-dependent kinase-like 3
    Names
    serine-threonine protein kinase NKIAMRE
    NP_001107047.1
    NP_001287782.1
    NP_001336292.1
    NP_001336293.1
    NP_001336294.1
    NP_001336295.1
    NP_057592.2
    XP_011541731.1
    XP_016865021.1
    XP_016865022.1
    XP_016865023.1
    XP_016865025.1
    XP_024301854.1
    XP_024301855.1
    XP_024301856.1
    XP_024301857.1
    XP_024301858.1
    XP_024301859.1
    XP_024301861.1
    XP_024301862.1
    XP_024301863.1
    XP_024301867.1
    XP_024301869.1
    XP_024301870.1
    XP_024301872.1
    XP_024301873.1
    XP_047273223.1
    XP_047273224.1
    XP_047273225.1
    XP_047273226.1
    XP_054208701.1
    XP_054208702.1
    XP_054208703.1
    XP_054208704.1
    XP_054208705.1
    XP_054208706.1
    XP_054208707.1
    XP_054208708.1
    XP_054208709.1
    XP_054208710.1
    XP_054208711.1
    XP_054208712.1
    XP_054208713.1
    XP_054208714.1
    XP_054208715.1
    XP_054208716.1
    XP_054208717.1
    XP_054208718.1
    XP_054208719.1
    XP_054208720.1
    XP_054208721.1
    XP_054208722.1
    XP_054208723.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_042179.2 RefSeqGene

      Range
      5005..77624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics), LRG_1006

    mRNA and Protein(s)

    1. NM_001113575.2 → NP_001107047.1  cyclin-dependent kinase-like 3 isoform 1

      See identical proteins and their annotated locations for NP_001107047.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC109454, BC041799, BX104333
      Consensus CDS
      CCDS47264.1
      UniProtKB/Swiss-Prot
      D3DQA0, D3DQA1, Q8IVW4, Q9P114
      UniProtKB/TrEMBL
      E7ET86
      Related
      ENSP00000265334.4, ENST00000265334.9
      Conserved Domains (1) summary
      cd07846
      Location:2 → 286
      STKc_CDKL2_3; Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase Like 2 and 3

    2. NM_001300853.2 → NP_001287782.1  cyclin-dependent kinase-like 3 isoform 3

      See identical proteins and their annotated locations for NP_001287782.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) has an alternate 5' exon, which results in a different 5' UTR and translation initiation at a downstream start codon, compared to variant 1. The resulting isoform (3) has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AK301802, AK310955, BC041799, BX104333
      Consensus CDS
      CCDS75303.1
      UniProtKB/TrEMBL
      B4DX41, B7Z2C5
      Related
      ENSP00000428500.1, ENST00000523054.5
      Conserved Domains (1) summary
      cl21453
      Location:1 → 97
      PKc_like; Protein Kinases, catalytic domain

    3. NM_001349363.2 → NP_001336292.1  cyclin-dependent kinase-like 3 isoform 4

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, initiates translation at a downstream start codon, and includes an alternate penultimate exon, compared to variant 1, resulting in a novel 3' coding region and longer 3' UTR, compared to variant 1. The resulting isoform (4) has a shorter N-terminus and a distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AK301802, AK310955, BC041799, BX104333, CR740901
      UniProtKB/TrEMBL
      B7Z2C5
      Conserved Domains (1) summary
      cl21453
      Location:1 → 97
      PKc_like; Protein Kinases, catalytic domain

    4. NM_001349364.2 → NP_001336293.1  cyclin-dependent kinase-like 3 isoform 5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR, lacks a portion of the 5' coding region, initiates translation at a downstream start codon, and includes an alternate penultimate exon, compared to variant 1, resulting in a novel 3' coding region and longer 3' UTR, compared to variant 1. The resulting isoform (5) has a shorter N-terminus and a distinct C-terminus compared to isoform 1. Variants 5, 6, and 7 encode the same isoform (5).
      Source sequence(s)
      AK294740, AK310955, BX104333, CR740901
      UniProtKB/TrEMBL
      B4DRK6

    5. NM_001349365.2 → NP_001336294.1  cyclin-dependent kinase-like 3 isoform 5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR, lacks a portion of the 5' coding region, initiates translation at a downstream start codon, and includes an alternate penultimate exon, compared to variant 1, resulting in a novel 3' coding region and longer 3' UTR, compared to variant 1. The resulting isoform (5) has a shorter N-terminus and a distinct C-terminus compared to isoform 1. Variants 5, 6, and 7 encode the same isoform (5).
      Source sequence(s)
      AK294740, BX104333, CR740901, DC372363
      UniProtKB/TrEMBL
      B4DRK6

    6. NM_001349366.2 → NP_001336295.1  cyclin-dependent kinase-like 3 isoform 5

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR, lacks a portion of the 5' coding region, initiates translation at a downstream start codon, and includes an alternate penultimate exon, compared to variant 1, resulting in a novel 3' coding region and longer 3' UTR, compared to variant 1. The resulting isoform (5) has a shorter N-terminus and a distinct C-terminus compared to isoform 1. Variants 5, 6, and 7 encode the same isoform (5).
      Source sequence(s)
      AK294740, BX104333, CR740901, DC353401
      UniProtKB/TrEMBL
      B4DRK6

    7. NM_016508.4 → NP_057592.2  cyclin-dependent kinase-like 3 isoform 2

      See identical proteins and their annotated locations for NP_057592.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR and has multiple coding region differences, compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC109454, AF130372, BC041799
      Consensus CDS
      CCDS47265.1
      UniProtKB/Swiss-Prot
      Q8IVW4
      Related
      ENSP00000430496.1, ENST00000523832.1
      Conserved Domains (2) summary
      smart00220
      Location:4 → 286
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd07846
      Location:2 → 286
      STKc_CDKL2_3; Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase Like 2 and 3

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      134283345..134371624 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024446091.2 → XP_024301859.1  cyclin-dependent kinase-like 3 isoform X5

      UniProtKB/TrEMBL
      E7ET86
      Conserved Domains (1) summary
      cl21453
      Location:2 → 298
      PKc_like; Protein Kinases, catalytic domain

    2. XM_024446093.2 → XP_024301861.1  cyclin-dependent kinase-like 3 isoform X7

      Conserved Domains (1) summary
      cl21453
      Location:77 → 182
      PKc_like; Protein Kinases, catalytic domain

    3. XM_024446099.2 → XP_024301867.1  cyclin-dependent kinase-like 3 isoform X11

      UniProtKB/TrEMBL
      B7Z2C5
      Conserved Domains (1) summary
      cl21453
      Location:1 → 97
      PKc_like; Protein Kinases, catalytic domain

    4. XM_024446101.2 → XP_024301869.1  cyclin-dependent kinase-like 3 isoform X11

      UniProtKB/TrEMBL
      B7Z2C5
      Conserved Domains (1) summary
      cl21453
      Location:1 → 97
      PKc_like; Protein Kinases, catalytic domain

    5. XM_024446104.2 → XP_024301872.1  cyclin-dependent kinase-like 3 isoform X11

      UniProtKB/TrEMBL
      B7Z2C5
      Conserved Domains (1) summary
      cl21453
      Location:1 → 97
      PKc_like; Protein Kinases, catalytic domain

    6. XM_024446086.2 → XP_024301854.1  cyclin-dependent kinase-like 3 isoform X1

      UniProtKB/TrEMBL
      E7ET86
      Conserved Domains (1) summary
      cd07846
      Location:2 → 298
      STKc_CDKL2_3; Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase Like 2 and 3

    7. XM_024446089.2 → XP_024301857.1  cyclin-dependent kinase-like 3 isoform X2

      UniProtKB/TrEMBL
      E7ET86
      Conserved Domains (1) summary
      cd07846
      Location:2 → 286
      STKc_CDKL2_3; Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase Like 2 and 3

    8. XM_024446087.2 → XP_024301855.1  cyclin-dependent kinase-like 3 isoform X1

      UniProtKB/TrEMBL
      E7ET86
      Conserved Domains (1) summary
      cd07846
      Location:2 → 298
      STKc_CDKL2_3; Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase Like 2 and 3

    9. XM_024446088.2 → XP_024301856.1  cyclin-dependent kinase-like 3 isoform X2

      UniProtKB/TrEMBL
      E7ET86
      Conserved Domains (1) summary
      cd07846
      Location:2 → 286
      STKc_CDKL2_3; Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase Like 2 and 3

    10. XM_011543429.3 → XP_011541731.1  cyclin-dependent kinase-like 3 isoform X1

      See identical proteins and their annotated locations for XP_011541731.1

      UniProtKB/TrEMBL
      E7ET86
      Conserved Domains (1) summary
      cd07846
      Location:2 → 298
      STKc_CDKL2_3; Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase Like 2 and 3

    11. XM_017009532.2 → XP_016865021.1  cyclin-dependent kinase-like 3 isoform X2

      UniProtKB/TrEMBL
      E7ET86
      Conserved Domains (1) summary
      cd07846
      Location:2 → 286
      STKc_CDKL2_3; Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase Like 2 and 3

    12. XM_017009536.2 → XP_016865025.1  cyclin-dependent kinase-like 3 isoform X6

      UniProtKB/TrEMBL
      E7ET86
      Conserved Domains (2) summary
      smart00220
      Location:4 → 243
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:2 → 276
      PKc_like; Protein Kinases, catalytic domain

    13. XM_024446095.2 → XP_024301863.1  cyclin-dependent kinase-like 3 isoform X10

      Conserved Domains (1) summary
      cl21453
      Location:2 → 298
      PKc_like; Protein Kinases, catalytic domain

    14. XM_017009533.2 → XP_016865022.1  cyclin-dependent kinase-like 3 isoform X3

      UniProtKB/TrEMBL
      E7ET86
      Conserved Domains (2) summary
      smart00220
      Location:4 → 298
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:2 → 298
      PKc_like; Protein Kinases, catalytic domain

    15. XM_017009534.2 → XP_016865023.1  cyclin-dependent kinase-like 3 isoform X4

      UniProtKB/TrEMBL
      E7ET86
      Conserved Domains (1) summary
      cd07846
      Location:2 → 298
      STKc_CDKL2_3; Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase Like 2 and 3

    16. XM_047417267.1 → XP_047273223.1  cyclin-dependent kinase-like 3 isoform X1

      UniProtKB/TrEMBL
      E7ET86

    17. XM_047417269.1 → XP_047273225.1  cyclin-dependent kinase-like 3 isoform X11

      UniProtKB/TrEMBL
      B7Z2C5

    18. XM_024446094.2 → XP_024301862.1  cyclin-dependent kinase-like 3 isoform X9

      UniProtKB/TrEMBL
      B7Z2C5
      Conserved Domains (1) summary
      cl21453
      Location:28 → 145
      PKc_like; Protein Kinases, catalytic domain

    19. XM_024446102.1 → XP_024301870.1  cyclin-dependent kinase-like 3 isoform X11

      UniProtKB/TrEMBL
      B7Z2C5
      Conserved Domains (1) summary
      cl21453
      Location:1 → 97
      PKc_like; Protein Kinases, catalytic domain

    20. XM_024446105.1 → XP_024301873.1  cyclin-dependent kinase-like 3 isoform X12

      UniProtKB/TrEMBL
      B4DRK6

    21. XM_024446090.2 → XP_024301858.1  cyclin-dependent kinase-like 3 isoform X4

      UniProtKB/TrEMBL
      E7ET86
      Related
      ENSP00000428689.1, ENST00000521118.5
      Conserved Domains (1) summary
      cd07846
      Location:2 → 298
      STKc_CDKL2_3; Catalytic domain of the Serine/Threonine Kinases, Cyclin-Dependent protein Kinase Like 2 and 3

    22. XM_047417268.1 → XP_047273224.1  cyclin-dependent kinase-like 3 isoform X8

    23. XM_047417270.1 → XP_047273226.1  cyclin-dependent kinase-like 3 isoform X13

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      134806646..134895410 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054352736.1 → XP_054208711.1  cyclin-dependent kinase-like 3 isoform X5

      UniProtKB/TrEMBL
      E7ET86

    2. XM_054352738.1 → XP_054208713.1  cyclin-dependent kinase-like 3 isoform X7

    3. XM_054352743.1 → XP_054208718.1  cyclin-dependent kinase-like 3 isoform X11

      UniProtKB/TrEMBL
      B7Z2C5

    4. XM_054352745.1 → XP_054208720.1  cyclin-dependent kinase-like 3 isoform X11

      UniProtKB/TrEMBL
      B7Z2C5

    5. XM_054352744.1 → XP_054208719.1  cyclin-dependent kinase-like 3 isoform X11

      UniProtKB/TrEMBL
      B7Z2C5

    6. XM_054352728.1 → XP_054208703.1  cyclin-dependent kinase-like 3 isoform X1

      UniProtKB/TrEMBL
      E7ET86

    7. XM_054352741.1 → XP_054208716.1  cyclin-dependent kinase-like 3 isoform X10

    8. XM_054352737.1 → XP_054208712.1  cyclin-dependent kinase-like 3 isoform X6

      UniProtKB/TrEMBL
      E7ET86

    9. XM_054352726.1 → XP_054208701.1  cyclin-dependent kinase-like 3 isoform X1

      UniProtKB/TrEMBL
      E7ET86

    10. XM_054352730.1 → XP_054208705.1  cyclin-dependent kinase-like 3 isoform X2

      UniProtKB/TrEMBL
      E7ET86

    11. XM_054352733.1 → XP_054208708.1  cyclin-dependent kinase-like 3 isoform X3

      UniProtKB/TrEMBL
      E7ET86

    12. XM_054352734.1 → XP_054208709.1  cyclin-dependent kinase-like 3 isoform X4

      UniProtKB/TrEMBL
      E7ET86

    13. XM_054352731.1 → XP_054208706.1  cyclin-dependent kinase-like 3 isoform X2

      UniProtKB/TrEMBL
      E7ET86

    14. XM_054352729.1 → XP_054208704.1  cyclin-dependent kinase-like 3 isoform X1

      UniProtKB/TrEMBL
      E7ET86

    15. XM_054352732.1 → XP_054208707.1  cyclin-dependent kinase-like 3 isoform X2

      UniProtKB/TrEMBL
      E7ET86

    16. XM_054352727.1 → XP_054208702.1  cyclin-dependent kinase-like 3 isoform X1

      UniProtKB/TrEMBL
      E7ET86

    17. XM_054352746.1 → XP_054208721.1  cyclin-dependent kinase-like 3 isoform X11

      UniProtKB/TrEMBL
      B7Z2C5

    18. XM_054352740.1 → XP_054208715.1  cyclin-dependent kinase-like 3 isoform X9

      UniProtKB/TrEMBL
      B7Z2C5

    19. XM_054352742.1 → XP_054208717.1  cyclin-dependent kinase-like 3 isoform X11

      UniProtKB/TrEMBL
      B7Z2C5

    20. XM_054352747.1 → XP_054208722.1  cyclin-dependent kinase-like 3 isoform X12

      UniProtKB/TrEMBL
      B4DRK6

    21. XM_054352735.1 → XP_054208710.1  cyclin-dependent kinase-like 3 isoform X4

      UniProtKB/TrEMBL
      E7ET86

    22. XM_054352739.1 → XP_054208714.1  cyclin-dependent kinase-like 3 isoform X8

    23. XM_054352748.1 → XP_054208723.1  cyclin-dependent kinase-like 3 isoform X13

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IVW4.1 GenPept UniProtKB/Swiss-Prot:Q8IVW4

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