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    CHRM5 cholinergic receptor muscarinic 5 [ Gallus gallus (chicken) ]

    Gene ID: 428881, updated on 3-Dec-2024

    Summary

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    Symbol
    CHRM5provided by CGNC
    Full Name
    cholinergic receptor muscarinic 5provided by CGNC
    Primary source
    CGNC:53502
    See related
    Ensembl:ENSGALG00010021107
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    CHKM5MR
    Orthologs
    human mouse all
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    Genomic context

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    See CHRM5 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (29566293..29614346, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (29548059..29596020, complement)

    Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene fibrinogen-like protein 1-like protein Neighboring gene ER membrane protein complex subunit 7 Neighboring gene apoptosis and caspase activation inhibitor Neighboring gene uncharacterized LOC112532478 Neighboring gene microRNA 6683 Neighboring gene ryanodine receptor 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation and functional characterization of the chick M5 muscarinic acetylcholine receptor gene. Creason S, et al. J Neurochem, 2000 Feb. PMID 10646542
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled acetylcholine receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables G protein-coupled serotonin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in gastric acid secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in dendrite IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    muscarinic acetylcholine receptor M5
    Names
    G-protein coupled neurotransmitter receptor
    M5 muscarinic acetylcholine receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001364658.2 → NP_001351587.1  muscarinic acetylcholine receptor M5

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000215
      UniProtKB/TrEMBL
      F1P0I0, Q9PTF6
      Related
      ENSGALP00010030288.1, ENSGALT00010051097.1
      Conserved Domains (2) summary
      cd14964
      Location:32 → 58
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:31 → 225
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      29566293..29614346 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040701123.2 → XP_040557057.1  muscarinic acetylcholine receptor M5 isoform X1

      UniProtKB/TrEMBL
      F1P0I0, Q9PTF6
      Conserved Domains (2) summary
      cd14964
      Location:32 → 58
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:31 → 225
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      29548059..29596020 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046918862.1 → XP_046774818.1  muscarinic acetylcholine receptor M5 isoform X1

      UniProtKB/TrEMBL
      F1P0I0, Q9PTF6

    2. XM_046918861.1 → XP_046774817.1  muscarinic acetylcholine receptor M5 isoform X1

      UniProtKB/TrEMBL
      F1P0I0, Q9PTF6
    Nucleotide Protein
    Heading Accession and Version

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    Molecular Biology Databases
    Research Materials