DMA major histocompatibility complex B, class II alpha chain DMA [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: DMAprovided by CGNC
Official Full Name: major histocompatibility complex B, class II alpha chain DMAprovided by CGNC
Primary source: CGNC:50421
See related: Ensembl:ENSGALG00010003090
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: BMA1; DMA1; B-DMA; B-MA1; MHCDMA; HLA-DMA; MHC-DMA
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Genomic context

Location:: chromosome: 16

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	16	NC_052547.1 (2204850..2207059)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	16	NC_052588.1 (1105978..1108187)

Chromosome 16 - NC_052547.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables MHC class II protein complex binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in antigen processing and presentation of exogenous peptide antigen via MHC class II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immunoglobulin production involved in immunoglobulin-mediated immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in peptide antigen assembly with MHC class II protein complex	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of T cell activation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of MHC class II protein complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: B locus M alpha chain 1

Names: MHC class II M alpha chain; MHC class II antigen; major histocompatibility complex, class II, DM alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001099353.2 → NP_001092823.1 B locus M alpha chain 1 precursor

See identical proteins and their annotated locations for NP_001092823.1

Status: VALIDATED

Source sequence(s)

JAENSK010000283

UniProtKB/TrEMBL

A5HUL6, B5BSK0, D0QTH0

Related

ENSGALP00010004325.1, ENSGALT00010007190.1

Conserved Domains (2) summary

cd05767
Location:115 → 208

IgC_MHC_II_alpha; Class II major histocompatibility complex (MHC) alpha chain immunoglobulin domain

smart00920
Location:29 → 108

MHC_II_alpha; Class II histocompatibility antigen, alpha domain