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    ERCC8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit [ Gallus gallus (chicken) ]

    Gene ID: 427153, updated on 3-Dec-2024

    Summary

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    Symbol
    ERCC8provided by CGNC
    Full Name
    ERCC excision repair 8, CSA ubiquitin ligase complex subunitprovided by CGNC
    Primary source
    CGNC:10925
    See related
    Ensembl:ENSGALG00010012669
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See ERCC8 in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (19481763..19521128, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (19481763..19521128, complement)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene microRNA 1584 Neighboring gene ELOVL fatty acid elongase 7 Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 2 Neighboring gene small integral membrane protein 15 Neighboring gene zinc finger SWIM-type containing 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transcription-coupled nucleotide-excision repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul4A-RING E3 ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of nucleotide-excision repair complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA excision repair protein ERCC-8
    Names
    Cockayne syndrome 1 protein
    excision repair cross-complementation group 8
    excision repair cross-complementing rodent repair deficiency, complementation group 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      19481763..19521128 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_424742.8 → XP_424742.1  DNA excision repair protein ERCC-8 isoform X1

      UniProtKB/TrEMBL
      A0A3Q2UP36, A0A8V0YGC8
      Related
      ENSGALP00010017584.1, ENSGALT00010030314.1
      Conserved Domains (3) summary
      COG2319
      Location:13 → 397
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:47 → 89
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:40 → 362
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. XM_046905800.1 → XP_046761756.1  DNA excision repair protein ERCC-8 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YGC8, E1C100
      Related
      ENSGALP00010017580.1, ENSGALT00010030307.1

    3. XM_040655970.2 → XP_040511904.1  DNA excision repair protein ERCC-8 isoform X3

      Conserved Domains (2) summary
      sd00039
      Location:47 → 89
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:40 → 287
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      19481763..19521128 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046936399.1 → XP_046792355.1  DNA excision repair protein ERCC-8 isoform X1

      UniProtKB/TrEMBL
      A0A3Q2UP36, A0A8V0YGC8

    2. XM_046936400.1 → XP_046792356.1  DNA excision repair protein ERCC-8 isoform X2

      UniProtKB/TrEMBL
      A0A8V0YGC8, E1C100

    3. XM_046936401.1 → XP_046792357.1  DNA excision repair protein ERCC-8 isoform X3

    Nucleotide Protein
    Heading Accession and Version

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