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    SMPD2 sphingomyelin phosphodiesterase 2 [ Gallus gallus (chicken) ]

    Gene ID: 770663, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SMPD2provided by CGNC
    Official Full Name
    sphingomyelin phosphodiesterase 2provided by CGNC
    Primary source
    CGNC:632
    See related
    Ensembl:ENSGALG00010026854
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    ISC1; nSMase
    Orthologs
    human mouse all
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    Genomic context

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    See SMPD2 in Genome Data Viewer
    Location:
    chromosome: 26
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 26 NC_052557.1 (77388..80809, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 26 NC_052598.1 (46465..49883, complement)

    Chromosome 26 - NC_052557.1Genomic Context describing neighboring genes Neighboring gene inositol 1,4,5-triphosphate receptor associated like Neighboring gene microtubule associated monooxygenase, calponin and LIM domain containing 1 Neighboring gene TEA domain transcription factor 3 Neighboring gene tubby like protein 1 Neighboring gene FK506 binding protein 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables sphingomyelin phosphodiesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    sphingomyelin phosphodiesterase 2
    Names
    neutral sphingomyelinase
    XP_001232516.1
    XP_004934842.1
    XP_015154246.1
    XP_040508741.1
    XP_040547189.1
    XP_040547190.1
    XP_040547192.1
    XP_040547193.1
    XP_046760149.1
    XP_046789058.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052557.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      77388..80809 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001232515.7 → XP_001232516.1  sphingomyelin phosphodiesterase 2 isoform X2

      See identical proteins and their annotated locations for XP_001232516.1

      UniProtKB/TrEMBL
      A0A1D5PL80
      Conserved Domains (1) summary
      cl00490
      Location:14 → 275
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    2. XM_046904193.1 → XP_046760149.1  sphingomyelin phosphodiesterase 2 isoform X1

    3. XM_015298760.4 → XP_015154246.1  sphingomyelin phosphodiesterase 2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PL80
      Conserved Domains (1) summary
      cl00490
      Location:14 → 275
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    4. XM_004934785.5 → XP_004934842.1  sphingomyelin phosphodiesterase 2 isoform X2

      See identical proteins and their annotated locations for XP_004934842.1

      UniProtKB/TrEMBL
      A0A1D5PL80
      Related
      ENSGALP00010039713.1, ENSGALT00010065144.1
      Conserved Domains (1) summary
      cl00490
      Location:14 → 275
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    5. XM_040652807.2 → XP_040508741.1  sphingomyelin phosphodiesterase 2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5PL80
      Conserved Domains (1) summary
      cl00490
      Location:14 → 275
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052598.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      46465..49883 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040691259.2 → XP_040547193.1  sphingomyelin phosphodiesterase 2 isoform X3

      Conserved Domains (1) summary
      cl00490
      Location:14 → 275
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    2. XM_040691255.2 → XP_040547189.1  sphingomyelin phosphodiesterase 2 isoform X2

      Conserved Domains (1) summary
      cl00490
      Location:14 → 275
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    3. XM_046933102.1 → XP_046789058.1  sphingomyelin phosphodiesterase 2 isoform X1

    4. XM_040691258.2 → XP_040547192.1  sphingomyelin phosphodiesterase 2 isoform X2

      Conserved Domains (1) summary
      cl00490
      Location:14 → 275
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    5. XM_040691256.2 → XP_040547190.1  sphingomyelin phosphodiesterase 2 isoform X2

      Conserved Domains (1) summary
      cl00490
      Location:14 → 275
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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